Effects of dexmedetomidine in morbidly obese patients undergoing laparoscopic gastric bypass

Middle East Journal of Anesthesiology

Volumn 19, Issue 3, 2007, Pages 537-551

  Bakhamees, Hassan S ^a   El Halafawy, Yasser M ^b   El Kerdawy, Hala M ^b   Gouda, Nevien M ^b   Altemyatt, Sultan ^a  

^a SAAD SPECIALIST HOSPITAL   (Saudi Arabia)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Dexmedetomidine; Fentanyl; Morphine; Obesity; Pain, postoperative; Propofol

Indexed keywords

ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANESTHETIC AGENT; DEXMEDETOMIDINE; INTRAVENOUS ANESTHETIC AGENT; MORPHINE; NARCOTIC ANALGESIC AGENT; PROPOFOL;

AGED; ARTICLE; BLOOD PRESSURE; BODY MASS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEART RATE; HUMAN; INTRAVENOUS ANESTHESIA; LAPAROSCOPY; MALE; MIDDLE AGED; MORBID OBESITY; PATIENT MONITORING; POSTOPERATIVE PAIN; PREMEDICATION; RANDOMIZED CONTROLLED TRIAL; ROUX Y ANASTOMOSIS; STOMACH BYPASS;

ADRENERGIC ALPHA-AGONISTS; AGED; ANALGESICS, OPIOID; ANASTOMOSIS, ROUX-EN-Y; ANESTHESIA, INTRAVENOUS; ANESTHETICS; ANESTHETICS, INTRAVENOUS; BLOOD PRESSURE; BODY MASS INDEX; DEXMEDETOMIDINE; FEMALE; GASTRIC BYPASS; HEART RATE; HUMANS; LAPAROSCOPY; MALE; MIDDLE AGED; MONITORING, INTRAOPERATIVE; MORPHINE; OBESITY, MORBID; PAIN, POSTOPERATIVE; PREANESTHETIC MEDICATION; PROPOFOL;

EID: 35948986261     PISSN: 05440440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. HOFER RE, SPRUNG J, SARR MG AND WEDEL DJ: Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics. Can J Anesth; 52:176-180, 2005.
2. FERNANDEZ AZ JR, DEMARIA EJ, TICHANSKY DS, KELLUM JM, WOLFE LG AND MEADOR J, ET AL: Multivariate analysis of risk factors for death following gastric bypass for treatment of morbid obesity. Ann Surg; 239:698-702, 2004.
3. UKLEJA A AND STONE RL: Medical and gastroenterologic management of the post-bariatric surgery patient. J Clin Gastroenterol; 38:312-321, 2004.
4. NGUYEN NT, LEE SL, GOLDMAN C, FLEMING N, ARANGO A AND MCFALL R, ET AL: Comparison of pulmonary function and postoperative pain after laparoscopic versus open gastric bypass: a randomized trial. J Am Coll Surg; 192:469-476, 2001.
5. VILA P, ESPACHS P, ECHEVARRIA V, GARCIA M, RINCON R AND VIDAL F: Acid aspiration prophylaxis in elective biliary surgery. A comparison of omeprazole and famotidine using manually aided gastric aspiration. Anaesthesia; 49:909-911, 1994.
6. SCHNEIDER MC: Anaesthetic management of high-risk obstetric patients. Acta Anaesthesial Scand Suppl; 111:163-165, 1997.
7. PIVALLZZA EG: Obesity and airway control. Anaesth Intensive Care; 22:315-316, 1994.
8. BENUMOF JL: Obstructive sleep apnea in the adult obese patient: implications for airway management. Anesthesiol Clin North America; 20:789-811, 2002.
9. KABON B, NAGELE A, REDDY D, EAGON C, FLESHMAN JW AND SESSLER DI, ET AL: Obesity decreases perioperative tissue oxygenation. Anesthesiology; 100:274-280, 2004.
10. JAVAHERI S, ABRAHAM WT, BROWN C, NISHIYAMA H, GIESTING R AND WAGONER LE: Prevalence of obstructive sleep apnoea and periodic limb movement in 45 subjects with heart transplantation. Eur Heart J; 25:260-266, 2004.
11. ESCLAMADO RM, GLENN MG, MCCULLOCH TM AND CUMMINGS CW: Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome. Laryngoscope; 99:1125-1129, 1989.
12. RAWAL N, SJOSTRAND U, CHRISTOFFERSON E, DAHLSTROM B, ARVILL A, RYDMAN H: Comparison of intramuscular and epidural morphine for postoperative analgesia in the grossly obese. Influence of postoperative ambulation and pulmonary function. Anesth Analg; 63:583-92, 1984.
13. VANUERCAR DH, MARTINEZ AP, DE LISSER EA: Sleep apnea syndromes: a potential contraindication for patient-controlled analgesia. Anesthesiology; 74:623-4, 1991.
14. WHITE PF: The role of non-opioid analgesic techniques in the management of pain after ambulatory surgery. Anesth Analg; 94:577-85, 2002.
15. GROUDINE SB, FISHER AG, KAUFMAN RP JR, ET AL: Intravenous lidocaine speeds the return of bowel function, decreases postoperative pain, and shortens hospital stay in patients undergoing radical retropublic prostatectomy. Anesth Analg; 86:235-9, 1998.
16. SCHULZ-STUBNER S, WETTMANN G, REYLE-HAHN SM, ROSSAINT R: Magnesium as part of balanced general anaesthesia with propofol, remifentanil and mivacurium: a double-blind randomized prospective study in 50 patients. Eur J Anaesthesiol; 18:723-9, 2001.
17. CASATI A, MAGISTRIS L, FANELLI G, ET AL: Small-dose clonidine prolongs postoperative analgesia after sciaticfemoral nerve block with 0.75% ropivacaine for foot surgery. Anesth Analg; 91:388-92, 2000.
18. ADRIAENSSENS G, VERMEYEN KM, HOFFMANN VLH, MERTENS E, ADRIAENSEN HF: Postoperative analgesia with i.v. patient-controlled morphine: effects of adding ketamine. Br J Anaesth; 83:393-6, 1999.
19. CHOW GK, FABRIZIO MD, STEER T, ET AL: Prospective double-blind study of effect of ketorolac administration after laparoscopic urologie surgery. J Endourol; 15:171-4, 2001.
20. ARAIN SR, RUEHLOW RM, UHRICH TD AND EBERT TJ: The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg; 98:153-158, 2004.
21. DUTTA S, KAROL MD, COHEN T, JONES RM AND MANT T: Effect of dexmedetomidine on propofol requirements in healthy subjects. J Pharm Sci; 90:172-181, 2001.
22. THORNTON C, LUCAS MA, NEWTON DE, DORE CJ AND JONES RM: Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 2: Auditory and somatosensory evoked responses. Br J Anaesth; 83:381-386, 1999.
23. CAMPBELL C, WEINGER MB AND QUINN M: Alterations in diaphragm EMG activity during opiate-induced respiratory depression. Respir Physiol; 100:107-117, 1995.
24. MAZE M, SCARFINI C AND CAVALIERE F: New agents for sedation in the intensive care unit. Crit Care Clin; 17:881-897, 2001.
25. SHERMAN C SMITH, CHARLES B EDWARDS GERALD N GOODMAN, ET AL: Open vs Laparoscopic Roux-en-Y Gastric Bypass: Comparison of Operative Morbidity and Mortality. Obes Surg: 14:73-76, 2004.
26. SALIHOGLU Z, KARACA S, KOSE Y, ZENGIN K AND TASKIN M: Total intravenous anesthesia versus single breath technique and anesthesia maintenance with sevoflurane for bariatric operations. Obes Surg; 11:496-501, 2001.
27. SUGERMAN HJ: Pulmonary function in morbid obesity. Gastroenterol Clin North Am; 16:25-37, 1987.
28. RESTA O, FOSCHINO-BARBARO MP, LEGARI G, ET AL: Sleep related breathing disorders, loud snoring and excessive daytime sleepiness in obese subjects. Int J Obesity; 25:669-75, 2001.
29. HOLMES J AND MAYE JP: Postoperative respiratory depression and unresponsiveness following epidural opiate administration: a case report. AanaJ; 72:126-128, 2004.
30. FELD JM, LAURITO CE, BECKERMAN M, VINCENT J AND HUFFMAN WE: Non-opioid analgesia improves pain relief and decreases sedation after gastric bypass surgery. Can J Anaesth; 50:336-341, 2003.
31. MIZOBET: Adrenergic receptor and alpha 2 agonist-4: applied and clinical pharmacology of alpha 2 agonist (Japanese). Masui; 46:1066-70, 1997.
32. KAMIBAYASHI T, MAZE M: Clinical use of alpha 2-adrenergic agonists. Anesthesiology; 93:1345-9, 2000.
33. BHANA N, GOA KL, MCCLELLAN KJ: Dexmedetomidine. Drugs; 59-263-8; discussion 269-70, 2000.
34. AHO MS, ERKOLA OA, SCHEININ H, LEHTINEN AM, KORTTILA KT: Effect of intravenously administered dexmedetomidine on pain after laparoscopic tubal ligation. Anesth Analg; 73:112-8, 1991.
35. AHO M, ERKOLA O, KALLIO A, SCHEININ H, KORTTILA K: Dexmedetomidine infusion for maintenance of anesthesia in patients undergoing abdominal hysterectomy. Anesth Analg; 75:940-6, 1992.
36. VENN RM, BRADSHAW CJ, SPENCER R, ET AL: Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit. Anaesthesia; 54:1136-42, 1999.
37. TRILTSCH AE, WELTE M, VON HOMEYER P, ET AL: Bispectral index-guided sedation with dexmedetomidine in intensive care: a prospective, randomized, double blind, placebo-controlled phase II study. Crit Care Med; 30:1007-14, 2002.
38. ARAIN SR, RUEHLOW RM, UHRICH TD, EBERT TJ: The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg; 98:153-8, 2004.
39. th Annual Meeting of the American Society for Bariatric Surgery; Las Vegas, Nevada; 2002.
40. FELD JM, HUFFMAN WE, STECHERT MM, HOFFMAN IW, ANANDA RC: Fentanyl or dexmedetomidine combined with desflurane for bariatric surgery. J Clin Anesth; 18(l):24-8, 2006.
41. DE WOLF AM, FRAGEN RJ, AVRAM MJ, PC FITZGERALD AND RAHIMI-DANESH F: The pharmacokinetics of dexmedetomidine in volunteers with severe renal impairment. Anesth Analg; 93:1205-1209,2001.