Single-Dose parenteral pharmacological interventions for the prevention of postoperative shivering: A quantitative systematic review of randomized controlled trials

Anesthesia and Analgesia

Volumn 99, Issue 3, 2004, Pages 718-727

  Kranke, Peter ^a   Eberhart, Leopold H ^b   Roewer, Norbert ^a   Tramèr, Martin R ^c  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CLONIDINE; DOLASETRON MESILATE; FLUMAZENIL; METHYLPHENIDATE; MIDAZOLAM; NEFOPAM; ONDANSETRON; PETHIDINE; PHYSOSTIGMINE; PLACEBO; TRAMADOL; URAPIDIL;

CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE CALCULATION; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFICACY; HUMAN; MAJOR CLINICAL STUDY; META ANALYSIS; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; REVIEW; RISK BENEFIT ANALYSIS; SHIVERING; SINGLE DRUG DOSE; STATISTICAL ANALYSIS; SYSTEMATIC REVIEW;

CLONIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; NEFOPAM; POSTOPERATIVE COMPLICATIONS; RANDOMIZED CONTROLLED TRIALS; SHIVERING;

EID: 4143052634     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ANE.0000130589.00098.CD     Document Type: Review

References (85)

1. Macintyre PE, Pavlin EG, Dwersteg JF. Effect of meperidine on oxygen consumption, carbon dioxide production, and respiratory gas exchange in postanesthesia shivering. Anesth Analg 1987;66:751-5.
2. Sessler DI. Temperature monitoring. In: Miller RD, ed. Anesthesia. New York: Churchill Livingstone, 1994:1363-82.
3. De Witte J, Sessler DI. Perioperative shivering: physiology and pharmacology. Anesthesiology 2002;96:467-84.
4. Kranke P, Eberhart LH, Roewer N, Tramèr MR. Pharmacological treatment of postoperative shivering: a quantitative systematic review of randomized controlled trials. Anesth Analg 2002; 94:453-60.
5. Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17:1-12.
6. Morris JA, Gardner MJ. Calculating confidence intervals for relative risk, odds ratio, and standardised ratios and rates. In: Altman DG, Gardner MJ, eds. Statistics with confidence: confidence intervals and statistical guidelines. London: BMJ Books, 1995:50-63.
7. Gavaghan DJ, Moore RA, McQuay HJ. An evaluation of homogeneity tests in meta-analyses in pain using simulations of individual patient data. Pain 2000;85:415-24.
8. Cook RJ, Sackett DL. The number needed to treat: a clinically useful measure of treatment effect. BMJ 1995;310:452-4.
9. Alfonsi P, Sessler DI, Du MB, et al. The effects of meperidine and sufentanil on the shivering threshold in postoperative patients. Anesthesiology 1998;89:43-8.
10. Apitzsch H, Olthoff D, Thieme V, et al. The effects of perioperative continuous administration of mivazerol on early postoperative hemodynamics and plasma catecholamines after major surgery. Anasthesiol Intensivmed Notfallmed Schmerzther 2000;35:515-22.
11. Flacke JW, Bloor BC, Flacke WE, et al. Reduced narcotic requirement by clonidine with improved hemodynamic and adrenergic stability in patients undergoing coronary bypass surgery. Anesthesiology 1987;67:11-9.
12. Hommeril JL, Bernard JM, Passuti N, et al. Effects of intravenous clonidine on postoperative shivering. Ann Fr Anesth Reanim 1991;10:554-8.
13. Jalonen J, Hynynen M, Kuitunen A, et al. Dexmedetomidine as an anesthetic adjunct in coronary artery bypass grafting. Anesthesiology 1997;86:331-45.
14. Kabutan K, Iwatsuki K, Nishimura Y, et al. The effect of vasodilator on the occurrence of postoperative shivering and the fall of core temperature. Masui 1997;46:669-73.
15. Kawaguchi M, Inoue S, Sakamoto T, et al. The effects of prostaglandin E1 on intraoperative temperature changes and the incidence of postoperative shivering during deliberate mild hypothermia for neurosurgical procedures. Anesth Analg 1999;88: 446-51.
16. Matsukawa T, Hanagata K, Kumazawa T, et al. The effect of prostaglandin E1 (PGE1) on body temperature and on postoperative shivering under high dose epidural fentanyl. Masui 1991;40:1495-502.
17. Paech MJ, Pavy TJ, Orlikowski CE, Evans SF. Patient-controlled epidural analgesia in labor: the addition of clonidine to bupivacaine-fentanyl. Reg Anesth Pain Med 2000;25:34-40.
18. Quintin L, Roudot F, Roux C, et al. Effect of clonidine on the circulation and vasoactive hormones after aortic surgery. Br J Anaesth 1991;66:108-15.
19. Quintin L, Viale JP, Annat G, et al. Oxygen uptake after major abdominal surgery: effect of clonidine. Anesthesiology 1991;74: 236-41.
20. Sahin A, Aypar Ü. Effect of amino acid solutions on intraoperative hypothermia and postoperative shivering. Acta Anaesthesiol Scand 2002;46:64-7.
21. Selldén E, Branstrom R, Brundin T. Preoperative infusion of amino acids prevents postoperative hypothermia. Br J Anaesth 1996;76:227-34.
22. Selldén E, Lindahl SG. Amino acid-induced thermogenesis reduces hypothermia during anesthesia and shortens hospital stay. Anesth Analg 1999;89:1551-6.
23. Breen TW, Janzen JA. Epidural fentanyl and caesarean section: when should fentanyl be given? Can J Anaesth 1992;39:317-22.
24. Chen JC, Hsu SW, Hu LH, et al. Intrathecal meperidine attenuates shivering induced by spinal anesthesia. Ma Zui Xue Za Zhi 1993;31:19-24.
25. Chow TC, Cho PH. The influence of small dose intrathecal fentanyl on shivering during transurethral resection of prostate under spinal anesthesia. Acta Anaesthesiol Sin 1994;32:165-70.
26. Chu CC, Shu SS, Lin SM, et al. The effect of intrathecal bupivacaine with combined fentanyl in cesarean section. Acta Anaesthesiol Sin 1995;33:149-54.
27. Lin BC, Lin PC, Lai YY, et al. The maternal and fetal effects of the addition of sufentanil to 0.5% spinal bupivacaine for cesarean delivery. Acta Anaesthesiol Sin 1998;36:143-8.
28. Liu WH, Luxton MC. The effect of prophylactic fentanyl on shivering in elective caesarean section under epidural analgesia. Anaesthesia 1991;46:344-8.
29. Palmer CM, Voulgaropoulos D, Alves D. Subarachnoid fentanyl augments lidocaine spinal anesthesia for cesarean delivery. Reg Anesth 1995;20:389-94.
30. Sutherland J, Seaton H, Lowry C. The influence of epidural pethidine on shivering during lower segment caesarean section under epidural anaesthesia. Anaesth Intensive Care 1991;19: 228-32.
31. Vettermann J, Thomas H, Lischke V, Asskali F. Repeated addition of fentanyl to bupivacaine peridural analgesia in labor: clinical action and fentanyl plasma level. Anaesthesist 1996;45: 428-36.
32. Mao CC, Tsou MY, Chia YY, et al. Pre-anesthetic oral clonidine is effective to prevent post-spinal shivering. Acta Anaesthesiol Sin 1998;36:137-42.
33. Camus Y, Delva E, Cohen S, Lienhart A. The effects of warming intravenous fluids on intraoperative hypothermia and postoperative shivering during prolonged abdominal surgery. Acta Anaesthesiol Scand 1996;40:779-82.
34. McEvoy MT, Carey TJ. Shivering and rewarming after cardiac surgery: comparison of ventilator circuits with humidifier and heated wires to heat and moisture exchangers. Am J Crit Care 1995;4:293-9.
35. Mort TC, Rintel TD, Altman F. The effects of forced-air warming on postbypass central and skin temperatures and shivering activity. J Clin Anesth 1996;8:361-70.
36. Bilotta F, Pietropaoli P, La Rossa I, et al. Effects of shivering prevention on haemodynamic and metabolic demands in hypothermic postoperative neurosurgical patients. Anaesthesia 2001; 56:514-9.
37. Yared JP, Starr NJ, Hoffmann-Hogg L, et al. Dexamethasone decreases the incidence of shivering after cardiac surgery: a randomized, double-blind, placebo-controlled study. Anesth Analg 1998;87:795-9.
38. Yared JP, Starr NJ, Torres FK, et al. Effects of single dose, postinduction dexamethasone on recovery after cardiac surgery. Ann Thorac Surg 2000;69:1420-4.
39. Brownridge P, Plummer J, Mitchell J, Marshall P. An evaluation of epidural bupivacaine with and without meperidine in labor. Reg Anesth 1992;17:15-21.
40. Frank T, Wehner M, Heinke W, Schmadicke I. Clonidine vs. midazolam for premedication: comparison of the anxiolytic effect by using the STAI-test. Anasthesiol Intensivmed Notfallmed Schmerzther 2002;37:89-93.
41. Brichard G, Johnstone M. The effect of methylphenidate (Ritalin) on post-halothane muscular spasticity. Br J Anaesth 1970;42:718-22.
42. Crossley AWA. Six months of shivering in a district general hospital. Anaesthesia 1992;47:845-8.
43. Goold JE. Postoperative spasticity and shivering: a review with personal observations of 500 patients. Anaesthesia 1984;39:35-8.
44. Hausmann D, Nadstawek J, Krajewski W. 02 uptake in the recovery period: the effect of the anesthetic procedure and the postoperative administration of pethidine. Anaesthesist 1991;40: 229-34.
45. Saltanov AI, Boshkoev ZB, Kadyrova EG. Analgesia and treatment of muscular shivering during the period of postanesthetic adaptation in oncologic patients. Anesteziol Reanimatol 1998;5: 32-5.
46. Shehabi Y, Gatt S, Buckman T, Isert P. Effect of adrenaline, fentanyl and warming of injectate on shivering following extradural analgesia in labour. Anaesth Intensive Care 1990;18:31-7.
47. Svetlov VA, Kozlov SP, Sarkisova NG, Vashchinskaia TV. Shivering and rigor during the awakening period. Anesteziol Reanimatol 1994;6:12-6.
48. Baxendale BR, Mahajan RP, Crossley AW. Anticholinergic premedication influences the incidence of postoperative shivering. Br J Anaesth 1994;72:291-4.
49. Erkola O, Korttila K, Aho M, et al. Comparison of intramuscular dexmedetomidine and midazolam premedication for elective abdominal hysterectomy. Anesth Analg 1994;79:646-53.
50. Frank T, Thieme V, Radow L. Premedication in maxillofacial surgery under total intravenous anesthesia: effects of clonidine compared to midazolam on the perioperative course. Anasthesiol Intensivmed Notfallmed Schmerzther 2000;35:428-34.
51. Wheelahan JM, Leslie K, Silbert BS. Epidural fentanyl reduces the shivering threshold during epidural lidocaine anesthesia. Anesth Analg 1998;87:587-90.
52. Zwischenberger JB, Kirsh MM, Dechert RE, et al. Suppression of shivering decreases oxygen consumption and improves hemodynamic stability during postoperative rewarming. Ann Thorac Surg 1987;43:428-31.
53. Sevarino FB, Johnson MD, Lema MJ, et al. The effect of epidural sufentanil on shivering and body temperature in the parturient. Anesth Analg 1989;68:530-3.
54. Bilotta F, Pietropaoli P, Sanita R, et al. Nefopam and tramadol for the prevention of shivering during neuraxial anesthesia. Reg Anesth Pain Med 2002;27:380-4.
55. Bock M, Sinner B, Göttlicher M, et al. Involvement of serotonergic pathways in postanaesthetic cold defence: dolasetron prevents shivering. J Thermal Biol 2002;27:159-66.
56. Buggy D, Higgins P, Moran C, et al. Clonidine at induction reduces shivering after general anaesthesia. Can J Anaesth 1997; 44:263-7.
57. Delaunay L, Bonnet F, Duvaldestin P. Clonidine decreases postoperative oxygen consumption in patients recovering from general anaesthesia. Br J Anaesth 1991;67:397-401.
58. de Witte J, Rietman GW, Vandenbroucke G, Deloof T. Postoperative effects of tramadol administered at wound closure. Eur J Anaesthesiol 1998;15:190-5.
59. Dodson ME, Fryer JM. Postoperative effects of methylphenidate. Br J Anaesth 1980;52:1265-70.
60. Eberhart LH, Novatchkov N, Schricker T, et al. Clonidine compared to midazolam for intravenous premedication for ambulatory procedures: a controlled double blind study in ASA 1 patients. Anasthesiol Intensivmed Notfallmed Schmerzther 2000;35:388-93.
61. Frank T, Thieme V, Olthoff D. Preoperative clonidine comedication within the scope of balanced inhalation anesthesia with sevoflurane in oral surgery procedures. Anaesthesiol Reanim 1999;24:65-70.
62. Grover VK, Mahajan R, Yaddanapudi LN, et al. Efficacy of midazolam in preventing postoperative shivering. Int J Clin Pharmacol Ther 2002;40:534-6.
63. Grundmann U, Berg K, Stamminger U, et al. Comparative study of pethidine and clonidine for prevention of postoperative shivering: a prospective, randomized, placebo-controlled double-blind study. Anasthesiol Intensivmed Notfallmed Schmerzther 1997;32:36-42.
64. Harris MM, Lawson D, Cooper CM, Ellis J. Treatment of shivering after epidural lidocaine. Reg Anesth 1989;14:13-8.
65. Horn EP, Werner C, Sessler DI, et al. Late intraoperative clonidine administration prevents postanesthetic shivering after total intravenous or volatile anesthesia. Anesth Analg 1997;84: 613-7.
66. Horn EP, Standl T, Sessler DI, et al. Physostigmine prevents postanesthetic shivering as does meperidine or clonidine. Anesthesiology 1998;88:108-13.
67. Hu LH, Chen JC, Lee Y, et al. Intramuscular meperidine for the prevention of shivering on spinal anesthesia. Ma Zui Xue Za Zhi 1992;30:223-8.
68. Mathews S, Al Mulla A, Varghese PK, et al. Postanaesthetic shivering: a new look at tramadol. Anaesthesia 2002;57:394-8.
69. Piper SN, Röhm KD, Maleck WH, et al. Dolasetron for preventing postanesthetic shivering. Anesth Analg 2002;94:106-11.
70. Piper SN, Fent MT, Röhm KD, et al. Urapidil does not prevent postanesthetic shivering: a dose-ranging study. Can J Anaesth 2001;48:742-7.
71. Piper SN, Maleck WH, Boldt J, et al. A comparison of urapidil, clonidine, meperidine and placebo in preventing postanesthetic shivering. Anesth Analg 2000;90:954-7.
72. Piper SN, Suttner SW, Schmidt CC, et al. Nefopam and clonidine in the prevention of postanaesthetic shivering. Anaesthesia 1999;54:695-9.
73. Piper SN, Schmidt CC, Suttner SW, et al. Prophylactic nefopam administration for post-anesthetic shivering. Anasthesiol Intensivmed Notfallmed Schmerzther 1998;33:786-9.
74. Powell RM, Buggy DJ. Ondansetron given before induction of anesthesia reduces shivering after general anesthesia. Anesth Analg 2000;90:1423-7.
75. Rosa G, Pinto G, Orsi P, et al. Control of post anaesthetic shivering with nefopam hydrochloride in mildly hypothermic patients after neurosurgery. Acta Anaesthesiol Scand 1995;39: 90-5.
76. Sia S. I.v. clonidine prevents post-extradural shivering. Br J Anaesth 1998;81:145-6.
77. Tempia A, Livigni S, Castino PM, et al. The use of nefopam in the prophylaxis and treatment of postoperative shivering. Minerva Anestesiol 1992;58:547-51.
78. Vanderstappen I, Vandermeersch E, Vanacker B, et al. The effect of prophylactic clonidine on postoperative shivering. Anaesthesia 1996;51:351-5.
79. Weinbroum AA, Gellee E. Flumazenil improves cognitive and neuromotor emergence and attenuates shivering after halothane-, enflurane- and isoflurane-based anesthesia. Can J Anaesth 2001;48:963-72.
80. Yang CH, Yu CC, Seah YS, et al. Effect of intravenous clonidine on prevention of postepidural shivering. Ma Zui Xue Za Zhi 1993;31:121-6.
81. Kurz A, Ikeda T, Sessler DI, et al. Meperidine decreases the shivering threshold twice as much as the vasoconstriction threshold. Anesthesiology 1997;86:1046-54.
82. Nicolaou G, Chen AA, Johnston CE, et al. Clonidine decreases vasoconstriction and shivering thresholds, without affecting the sweating threshold. Can J Anaesth 1997;44:636-42.
83. Song F, Altman DG, Glenny AM, Deeks JJ. Validity of indirect comparison for estimating efficacy of competing interventions: empirical evidence from published meta-analyses. BMJ 2003; 326:472.
84. Buggy DJ, Crossley AW. Thermoregulation, mild perioperative hypothermia and postanaesthetic shivering. Br J Anaesth 2000; 84:615-28.
85. Stevens RD, Burri H, Tramèr MR. Pharmacologic myocardial protection in patients undergoing noncardiac surgery: a quantitative systematic review. Anesth Analg 2003;97:623-33.