Reduction in the incidence of shivering with perioperative dexmedetomidine: A randomized prospective study

Journal of Anaesthesiology Clinical Pharmacology

Volumn 28, Issue 1, 2012, Pages 86-91

  Singh Bajwa, Sukhminder Jit ^a   Gupta, Sachin ^a   Kaur, Jasbir ^a   Singh, Amarjit ^a   Parmar, S S ^a  

^a GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL   (India)

Author keywords

Dexmedetomidine; hypothermia; shivering; tramadol

Indexed keywords

DEXMEDETOMIDINE; ONDANSETRON; TRAMADOL;

ADULT; ANESTHESIA LEVEL; ARTICLE; BODY TEMPERATURE MEASUREMENT; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; FEMALE; GENERAL ANESTHESIA; HEART RATE VARIABILITY; HUMAN; LAPAROSCOPIC SURGERY; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; OUTCOME ASSESSMENT; PERIOPERATIVE PERIOD; POSTOPERATIVE NAUSEA AND VOMITING; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SEDATION; SHIVERING; SIDE EFFECT; XEROSTOMIA;

EID: 84863278353     PISSN: 09709185     EISSN: 22312730     Source Type: Journal    
DOI: 10.4103/0970-9185.92452     Document Type: Article

References (44)

1. Giesbrecht GG, Sessler DI, Mekjavic IB, Schroeder M, Bristow GW. Treatment of immersion hypothermia by direct body-to-body contact. J Appl Physiol 1994;76:2373-9. (Pubitemid 24184755)
2. Henneman E. Organization of the motoneuron pool: The size principle, Medical Physiology. 14 th ed. Mountcastle VB, editor. St. Louis: CV Mosby; 1980. p. 718-41.
3. Kranke P, Eberhart LH, Roewer N, Tramer MR. Pharma-cological treatment of postoperative shivering a quan-titative systemic review of randomized controlled trials. Anesth Analg 2002;94:453-60. (Pubitemid 34106848)
4. Powell R, Buggy D. Ondansetron given before induc-tion of anesthesia reduces shivering after general anes-thesia. Anesth Analg 2000;90:1413-7.
5. Ciofolo MJ, Clergue F, Devilliers C, Ben Ammar M, Viars P. Changes in ven-tilation, oxygen uptake and carbon dioxide output dur-ing recovery from isoflurane anesthesia. Anesthesiol-ogy 1989;70:737-41. (Pubitemid 19129025)
6. Piper SN, Maleck WH, Boldt J, suttner SW, Schmidt CC, Reich DG. A comparison of clonidine, meperidine and placebo in preventing postanesthetic shivering. Anesth Analg 2000;90:954-7. (Pubitemid 30190808)
7. Alfonsi P. Postanesthetic shivering epidemiology, patho-physiology and approaches to prevention and manage-ment. Drugs 2001;61:2193-205.
8. Bajwa SJ, Bajwa SK, Kaur J, Singh G, Arora V, Gupta S, et al. Dexmedetomidine and clonidine in epidural anaesthesia: A comparative evaluation. Indian J Anaesth 2011;55:116-21.
9. Linde H e Mo. The clinical use of dexmedetomidine. Rev Bras Anestesiol 2004;54:1-4.
10. Ribeiro RN, Nascimento JP. The use of dexmedetomidine in anesthesiology. Rev Bras Anestesiol 2003;53:97-113.
11. Hall JE, Uhrich TD, Barney JA, Arain SR, Ebert TJ. Sedative, amnesic, and analgesic properties of small-dose dexmedetomidine infusions. Anesth Analg 2000;90:699-705. (Pubitemid 30117535)
12. Kamibayashi T, Maze M. Clinical uses of alpha-2 adrenergic agonists. Anaesthesiology 2000;93:1345-9.
13. Talke P, Tayefeh F, Sessler DI, Jeffrey R, Noursalehi M, Richardson C. Dexmedetomidine does not alter the sweating threshold, but comparably and linearly reduces the vasoconstriction and shivering thresholds. Anesthesiology 1997; 87:835-41. (Pubitemid 27456236)
14. Quan N, Xin L, Ungar AL, Blatteis CM. Preoptic norepinephrine-induced hypothermia is mediated by α2-adrenoceptors. Am J Physiol 1992;262:R407-11.
15. Buggy D, Higgens P, Moran C, O'Donovan F, Mc Carroll M. Clonidine at induction reduces shivering after gen-eral anesthesia. Can J Anaesth 1997;44:263-7. (Pubitemid 27298896)
16. Piper SN, Rohm KD, Suttner SW, Maleck WH, Kranke P, Boldt J. A comparison of nefopam and clonidine for the prevention of postanesthetic shivering: A comparative, double blind and placebo controlled dose ranging study. Anaesthesia 2004;59:559-64.
17. Kranke P, Eberhart LH, Roewer N, Tramer MR. Single dose parenteral pharmacological interventions for the prevention of postoperative shivering: A quantitative systematic review of randomized controlled trials. Anesth Analg 2004;99:718-27. (Pubitemid 39100360)
18. Witte JD, Sessler DI. Perioperative shivering physi-ology and pharmacology. Anesthesiology 2002;96:467-84.
19. Katyal S, Tewari A. Shivering: Anesthetic Considerations. J Anaesth Clin Pharmacol 2002; 18(4): 363-76.
20. Sessler DI. Temperature Monitoring. Textbook of Anaesthesia. Miller RD, editor. 5 th ed. Philadelphia: Churchill Livingstone Inc.; 1994. p. 1367-89.
21. Mathews S, Al Mulla A, Varghese PK, Radim K, Mumtaz S. Postanaesthetic shivering-a new look at Tramadol. Anaesthesia 2002;57:387-403.
22. Vanderstappen I, Vanermeerch E, Vanacker B, Mattheussen M, Herijgers P, Van Aken H. The effect of prophylactic clonidine on postoperative shivering: A large prospective double-blind study. Anaesthesia 1996;51:351-5. (Pubitemid 26122998)
23. Kurz A, Ikeda T, Sessler DI, Larson M, Bjorksten AR, Dechert M, et al. Meperidine decreases the shivering threshold twice as much as the vasoconstriction threshold. Anesthesiology 1997;86:1046-54. (Pubitemid 27208901)
24. Takada K, Clark DJ, Davies MF, Tonner PH, Krause TK, Bertaccini E, et al. Meperidine exerts agonist activity at the a 2B-adrenoceptor subtype. Anesthesiology 2002;96:1420-6. (Pubitemid 34587211)
25. Mokhtarani M, Mahgoub AN, Morioka N, Doufas AG, Sessler DI. Buspirone and meperidine synergistically reduce the shivering threshold. Anesth Analg 2001;93:1233-9. (Pubitemid 33021023)
26. Ebert TJ, Hall JE, Barney JA, Uhrich TD, Colinco MD. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology 2000;93:382-94. (Pubitemid 30620311)
27. Boulant JA. The effect of firing rate on preoptic neuronal thermosensitivity. J Physiol 1974;240:661-9.
28. Maze M, Tranquilli W. Alpha-2 adrenoceptor agonists: Defining the role in clinical anesthesia. Anesthesiology 1991;74:581-605.
29. Surprenant A, North RA. Mechanism of synaptic inhibition by noradrenaline acting at α2-adrenoceptors. Proc R Soc Biol 1988;234:85-114.
30. Evans RJ, Surprenant A. Effects of phospholipase A2 inhibitors on coupling of α2-adrenoceptors to inwardly rectifying potassium currents in guinea pig submucosal neurones. Br J Pharmacol 1993;10:591-6. (Pubitemid 23279264)
31. Maze M. Clinical uses of alpha-2 agonists, 46 th Annual Refresher Course Lectures. Atlanta: American Society of Anesthesiologists; 1995. p. 125.
32. Lipscombe D, Kongsamut S, Tsien RW. α-adrenergic inhibition of sympathetic neurotransmitter release mediated by modulation of N-type calcium-channel gating. Nature 1989;340:639-42. (Pubitemid 19202573)
33. Myers RD, Simpson CW, Higgins D, Nattermann RA, Rice JC, Redgrave P, et al. Hypothalamic Na+ and Ca++ ions and temperature set-point: New mechanisms of action of a central or peripheral thermal challenge and intrahypothalamic 5-HT, NE, PGE1, and pyrogen. Brain Res Bull 1976;1:301-27.
34. Alojado ME, Ohta Y, Kemmotsu O. The effect of clonidine on the activity of neurons in the rat dorsal raphe nucleus in vitro. Anesth Analg 1994;79:257-60. (Pubitemid 24240860)
35. De Witte J, Sessler DI. Perioperative shivering: Physiology and Pharmacology. Anaesthesiology 2002;96:467-84.
36. Bajwa SS, Bajwa SK, Kaur J, Sharma V, Singh A, Singh A, et al. Palonosetron: A novel approach to control postoperative nausea and vomiting in day care surgery. Saudi J Anaesth 2011;5:19-24.
37. Bock M, Sinner B, Gottlicher M, Simon E, Martin E, Motsch J. Involvement of serotonergic pathways in pos-tanesthetic cold defence: Dolasetron prevents shiver-ing. J Thermal Biol 2002;27:159-66. (Pubitemid 34196781)
38. Wrench IJ, Cavill G, Ward JE, Crossley AW. Com-parison between alfentanil, pethidine and placebo in the treatment of postanesthetic shivering. Br J Anaesth 1997;79:541-2. (Pubitemid 27423338)
39. Terasako K, Yamamoto M. Comparison between pentazo-cine, pethidine and placebo in the treatment of postanes-thetic shivering. Acta Anaesthesiol Scand 2000;44:311-2. (Pubitemid 30131368)
40. De Witte J, Deloof T, De Veylder J, Housemans PR. Tramadol is the treatment of postanaesthetic shivering. Acta Anaesthesiol Scandinavica 1997;41:506-10.
41. Saha E, Ray M, Mukherjee G. Effect of tramadol in prevention of postanaesthetic shivering following general anaesthesia for cholecystectomy. Indian J Anaesth 2005;49:208-12.
42. Raffa RB, Friderichs E, Reimann W, Shank RP, Codd EE, Vaught JL. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an "atypical" opioid analgesic. J Pharmacol Exp Ther 1992;260:275-85.
43. Frink MC, Hennies HH, Englberger W, Haurand M, Wilffert B. Influence of tramadol on neurotransmitter systems of the rat brain. Arzneimittelforschung 1996;46:1029-36. (Pubitemid 26391736)
44. De Witte JL, Kim JS, Sessler DI, Bastanmehr H, Bjorksten AR. Tramadol reduces the shivering, vasoconstriction, and sweating thresholds. Anesth Analg 1998;87:173-9. (Pubitemid 28311634)