A dynamic relationship between mucosal T helper type 17 and regulatory T-cell populations in nasopharynx evolves with age and associates with the clearance of pneumococcal carriage in humans

Clinical Microbiology and Infection

Volumn 22, Issue 8, 2016, Pages 736.e1-736.e7

  Mubarak, A ^a   Ahmed, M S ^a   Upile, N ^b   Vaughan, C ^b   Xie, C ^b   Sharma, R ^b   Acar, P ^c   McCormick, M S ^c   Paton, J C ^d   Mitchell, T ^e   Cunliffe, N ^a   Zhang, Q ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b ALDER HEY CHILDREN S HOSPITAL   (United Kingdom)

^c ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

^d UNIVERSITY OF ADELAIDE   (Australia)

^e UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Children and adults; Cytokine response; Mucosal T helper type 17; Nasopharynx associated lymphoid tissue; Pneumococcal carriage; Streptococcus pneumoniae; T regulatory cells

Indexed keywords

CD4 ANTIGEN; CD45RO ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 22; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN 7 RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR; CYTOKINE;

ADOLESCENT; ADULT; AGE DISTRIBUTION; ARTICLE; BACTERIAL CLEARANCE; BACTERIUM CARRIER; CELL STIMULATION; CHILD; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE ASSOCIATION; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE SUBPOPULATION; LYMPHOID TISSUE; MAJOR CLINICAL STUDY; MALE; MEMORY T LYMPHOCYTE; MOLECULAR DYNAMICS; MOLECULAR EVOLUTION; MUCOSA CELL; NASOPHARYNX; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; STREPTOCOCCUS PNEUMONIAE; TH17 CELL; TONSIL CELL; AGE; HETEROZYGOTE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; METABOLISM; MICROBIOLOGY; PNEUMOCOCCAL INFECTION; PRESCHOOL CHILD; RESPIRATORY MUCOSA; T LYMPHOCYTE SUBPOPULATION; YOUNG ADULT;

ADOLESCENT; ADULT; AGE FACTORS; CARRIER STATE; CHILD; CHILD, PRESCHOOL; CYTOKINES; FEMALE; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MALE; NASOPHARYNX; PNEUMOCOCCAL INFECTIONS; RESPIRATORY MUCOSA; STREPTOCOCCUS PNEUMONIAE; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; YOUNG ADULT;

EID: 84991107993     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2016.05.017     Document Type: Article

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