Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function

Cell Metabolism

Volumn 24, Issue 2, 2016, Pages 332-340

  Moon, Hyo Youl ^a   Becke, Andreas ^b   Berron, David ^b   Becker, Benjamin ^a   Sah, Nirnath ^a   Benoni, Galit ^a   Janke, Emma ^a   Lubejko, Susan T ^a   Greig, Nigel H ^a   Mattison, Julie A ^a   Duzel, Emrah ^b,c   van Praag, Henriette ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

Author keywords

cathepsin B; exercise; hippocampus; humans; memory; mice; muscle

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CATHEPSIN B; DOUBLECORTIN; DOUBLECORTIN PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NEUROPEPTIDE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL ANALYSIS; BLOOD BRAIN BARRIER; BLOOD LEVEL; CELL CULTURE; COGNITION; CONDITIONED MEDIUM; CONTROLLED STUDY; DENTATE GYRUS; EXERCISE; FEMALE; GASTROCNEMIUS MUSCLE; GRANULE CELL; HIPPOCAMPUS; HUMAN; MALE; MEMORY; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEOMICS; RHESUS MONKEY; RUNNING; SKELETAL MUSCLE CELL; SPATIAL MEMORY; STEM CELL; TREADMILL EXERCISE; AFFECT; AGING; ANIMAL; ANIMAL BEHAVIOR; BLOOD; C57BL MOUSE; EXERCISE TEST; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; REPRODUCIBILITY; SECRETION (PROCESS); SEDENTARY LIFESTYLE; YOUNG ADULT;

ADULT; AFFECT; AGING; ANIMALS; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; CATHEPSIN B; COGNITION; EXERCISE TEST; FEMALE; HIPPOCAMPUS; HUMANS; MACACA MULATTA; MALE; MEMORY; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; MOTOR ACTIVITY; NEUROGENESIS; NEURONS; NEUROPEPTIDES; PHYSICAL CONDITIONING, ANIMAL; REPRODUCIBILITY OF RESULTS; RUNNING; SEDENTARY LIFESTYLE; YOUNG ADULT;

EID: 84991055997     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2016.05.025     Document Type: Article

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