-
1
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H, Del Tredici K, Rub U, de Vos RA, Jansen Steur EN, Braak E. 2003. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24:197–211.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
2
-
-
77957347060
-
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro
-
Burre J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Sudhof TC. 2010. Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Science 329:1663–1667.
-
(2010)
Science
, vol.329
, pp. 1663-1667
-
-
Burre, J.1
Sharma, M.2
Tsetsenis, T.3
Buchman, V.4
Etherton, M.R.5
Sudhof, T.C.6
-
3
-
-
0037109727
-
Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein
-
Cabin DE, Shimazu K, Murphy D, Cole NB, Gottschalk W, McIlwain KL, Orrison B, Chen A, Ellis CE, Paylor R, Lu B, Nussbaum RL. 2002. Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein. J Neurosci 22:8797–8807.
-
(2002)
J Neurosci
, vol.22
, pp. 8797-8807
-
-
Cabin, D.E.1
Shimazu, K.2
Murphy, D.3
Cole, N.B.4
Gottschalk, W.5
McIlwain, K.L.6
Orrison, B.7
Chen, A.8
Ellis, C.E.9
Paylor, R.10
Lu, B.11
Nussbaum, R.L.12
-
5
-
-
79959606473
-
Axonopathy is a compounding factor in the pathogenesis of Krabbe disease
-
Castelvetri LC, Givogri MI, Zhu HL, Smith B, Lopez-Rosas A, Qiu X, van Breemen R, Bongarzone ER. 2011. Axonopathy is a compounding factor in the pathogenesis of Krabbe disease. Acta Neuropathol 122:35–48.
-
(2011)
Acta Neuropathol
, vol.122
, pp. 35-48
-
-
Castelvetri, L.C.1
Givogri, M.I.2
Zhu, H.L.3
Smith, B.4
Lopez-Rosas, A.5
Qiu, X.6
van Breemen, R.7
Bongarzone, E.R.8
-
6
-
-
84878890357
-
The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors
-
Castelvetri LC, Givogri MI, Hebert A, Smith B, Song Y, Kaminska A, Lopez-Rosas A, Morfini G, Pigino G, Sands M, Brady ST, Bongarzone ER. 2013. The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors. J Neurosci 33:10048–10056.
-
(2013)
J Neurosci
, vol.33
, pp. 10048-10056
-
-
Castelvetri, L.C.1
Givogri, M.I.2
Hebert, A.3
Smith, B.4
Song, Y.5
Kaminska, A.6
Lopez-Rosas, A.7
Morfini, G.8
Pigino, G.9
Sands, M.10
Brady, S.T.11
Bongarzone, E.R.12
-
7
-
-
19244362249
-
Molecular heterogeneity of late-onset forms of globoid-cell leukodystrophy
-
De Gasperi R, Gama Sosa MA, Sartorato EL, Battistini S, MacFarlane H, Gusella JF, Krivit W, Kolodny EH. 1996. Molecular heterogeneity of late-onset forms of globoid-cell leukodystrophy. Am J Hum Genet 59:1233–1242.
-
(1996)
Am J Hum Genet
, vol.59
, pp. 1233-1242
-
-
De Gasperi, R.1
Gama Sosa, M.A.2
Sartorato, E.L.3
Battistini, S.4
MacFarlane, H.5
Gusella, J.F.6
Krivit, W.7
Kolodny, E.H.8
-
8
-
-
3342951965
-
Lipid rafts mediate the synaptic localization of alpha-synuclein
-
Fortin DL, Troyer MD, Nakamura K, Kubo S, Anthony MD, Edwards RH. 2004. Lipid rafts mediate the synaptic localization of alpha-synuclein. J Neurosci 24:6715–6723.
-
(2004)
J Neurosci
, vol.24
, pp. 6715-6723
-
-
Fortin, D.L.1
Troyer, M.D.2
Nakamura, K.3
Kubo, S.4
Anthony, M.D.5
Edwards, R.H.6
-
9
-
-
78649790233
-
Sphingolipids in neurodegeneration
-
Haughey NJ. 2010. Sphingolipids in neurodegeneration. Neuromol Med 12:301–305.
-
(2010)
Neuromol Med
, vol.12
, pp. 301-305
-
-
Haughey, N.J.1
-
10
-
-
84859554327
-
Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-beta peptide
-
Keilani S, Lun Y, Stevens AC, Williams HN, Sjoberg ER, Khanna R, Valenzano KJ, Checler F, Buxbaum JD, Yanagisawa K, Lockhart DJ, Wustman BA, Gandy S. 2012. Lysosomal dysfunction in a mouse model of Sandhoff disease leads to accumulation of ganglioside-bound amyloid-beta peptide. J Neurosci 32:5223–5236.
-
(2012)
J Neurosci
, vol.32
, pp. 5223-5236
-
-
Keilani, S.1
Lun, Y.2
Stevens, A.C.3
Williams, H.N.4
Sjoberg, E.R.5
Khanna, R.6
Valenzano, K.J.7
Checler, F.8
Buxbaum, J.D.9
Yanagisawa, K.10
Lockhart, D.J.11
Wustman, B.A.12
Gandy, S.13
-
11
-
-
0023722437
-
Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal
-
Maroteaux L, Campanelli JT, Scheller RH. 1988. Synuclein: a neuron-specific protein localized to the nucleus and presynaptic nerve terminal. J Neurosci 8:2804–2815.
-
(1988)
J Neurosci
, vol.8
, pp. 2804-2815
-
-
Maroteaux, L.1
Campanelli, J.T.2
Scheller, R.H.3
-
12
-
-
84859928720
-
Examining the mechanisms that link beta-amyloid and alpha-synuclein pathologies
-
Marsh SE, Blurton-Jones M. 2012. Examining the mechanisms that link beta-amyloid and alpha-synuclein pathologies. Alzheimers Res Ther 4:11.
-
(2012)
Alzheimers Res Ther
, vol.4
, pp. 11
-
-
Marsh, S.E.1
Blurton-Jones, M.2
-
13
-
-
33847022701
-
GM1 specifically interacts with alpha-synuclein and inhibits fibrillation
-
Martinez Z, Zhu M, Han SB, Fink AL. 2007. GM1 specifically interacts with alpha-synuclein and inhibits fibrillation. Biochemistry 46:1868–1877.
-
(2007)
Biochemistry
, vol.46
, pp. 1868-1877
-
-
Martinez, Z.1
Zhu, M.2
Han, S.B.3
Fink, A.L.4
-
14
-
-
84871406157
-
Amyloid-beta metabolism in Niemann-Pick C disease models and patients
-
Mattsson N, Olsson M, Gustavsson MK, Kosicek M, Malnar M, Mansson JE, Blomqvist M, Gobom J, Andreasson U, Brinkmalm G, Vite C, Hecimovic S, Hastings C, Blennow K, Zetterberg H, Portelius E. 2012. Amyloid-beta metabolism in Niemann-Pick C disease models and patients. Metab Brain Dis 27:573–585.
-
(2012)
Metab Brain Dis
, vol.27
, pp. 573-585
-
-
Mattsson, N.1
Olsson, M.2
Gustavsson, M.K.3
Kosicek, M.4
Malnar, M.5
Mansson, J.E.6
Blomqvist, M.7
Gobom, J.8
Andreasson, U.9
Brinkmalm, G.10
Vite, C.11
Hecimovic, S.12
Hastings, C.13
Blennow, K.14
Zetterberg, H.15
Portelius, E.16
-
15
-
-
79960009804
-
Gaucher disease glucocerebrosidase and alpha-synuclein form a bidirectional pathogenic loop in synucleinopathies
-
Mazzulli JR, Xu YH, Sun Y, Knight AL, McLean PJ, Caldwell GA, Sidransky E, Grabowski GA, Krainc D. 2011. Gaucher disease glucocerebrosidase and alpha-synuclein form a bidirectional pathogenic loop in synucleinopathies. Cell 146:37–52.
-
(2011)
Cell
, vol.146
, pp. 37-52
-
-
Mazzulli, J.R.1
Xu, Y.H.2
Sun, Y.3
Knight, A.L.4
McLean, P.J.5
Caldwell, G.A.6
Sidransky, E.7
Grabowski, G.A.8
Krainc, D.9
-
16
-
-
66249118697
-
Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy
-
Ohmi K, Kudo LC, Ryazantsev S, Zhao HZ, Karsten SL, Neufeld EF. 2009. Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy. Proc Natl Acad Sci U S A 106:8332–8337.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8332-8337
-
-
Ohmi, K.1
Kudo, L.C.2
Ryazantsev, S.3
Zhao, H.Z.4
Karsten, S.L.5
Neufeld, E.F.6
-
17
-
-
84893677855
-
Characterization and application of a disease-cell model for a neurodegenerative lysosomal disease
-
Ribbens JJ, Moser AB, Hubbard WC, Bongarzone ER, Maegawa GH. 2014. Characterization and application of a disease-cell model for a neurodegenerative lysosomal disease. Mol Genet Metab 111:172–183.
-
(2014)
Mol Genet Metab
, vol.111
, pp. 172-183
-
-
Ribbens, J.J.1
Moser, A.B.2
Hubbard, W.C.3
Bongarzone, E.R.4
Maegawa, G.H.5
-
18
-
-
84864258151
-
alpha-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis
-
Scott D, Roy S. 2012. alpha-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis. J Neurosci 32:10129–10135.
-
(2012)
J Neurosci
, vol.32
, pp. 10129-10135
-
-
Scott, D.1
Roy, S.2
-
19
-
-
79960360692
-
Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond
-
Shachar T, Lo Bianco C, Recchia A, Wiessner C, Raas-Rothschild A, Futerman AH. 2011. Lysosomal storage disorders and Parkinson's disease: Gaucher disease and beyond. Mov Disord 26:1593–1604.
-
(2011)
Mov Disord
, vol.26
, pp. 1593-1604
-
-
Shachar, T.1
Lo Bianco, C.2
Recchia, A.3
Wiessner, C.4
Raas-Rothschild, A.5
Futerman, A.H.6
-
20
-
-
84895927010
-
Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease
-
Smith BR, Santos MB, Marshall MS, Cantuti-Castelvetri L, Lopez-Rosas A, Li G, van Breemen R, Claycomb KI, Gallea JI, Celej SM, Crocker S, Givogri MI, Bongarzone ER. 2014. Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease. J Pathol 232:509–521.
-
(2014)
J Pathol
, vol.232
, pp. 509-521
-
-
Smith, B.R.1
Santos, M.B.2
Marshall, M.S.3
Cantuti-Castelvetri, L.4
Lopez-Rosas, A.5
Li, G.6
van Breemen, R.7
Claycomb, K.I.8
Gallea, J.I.9
Celej, S.M.10
Crocker, S.11
Givogri, M.I.12
Bongarzone, E.R.13
-
22
-
-
66049163058
-
Psychosine accumulates in membrane microdomains in the brain of krabbe patients, disrupting the raft architecture
-
White AB, Givogri MI, Lopez-Rosas A, Cao H, van Breemen R, Thinakaran G, Bongarzone ER. 2009. Psychosine accumulates in membrane microdomains in the brain of krabbe patients, disrupting the raft architecture. J Neurosci 29:6068–6077.
-
(2009)
J Neurosci
, vol.29
, pp. 6068-6077
-
-
White, A.B.1
Givogri, M.I.2
Lopez-Rosas, A.3
Cao, H.4
van Breemen, R.5
Thinakaran, G.6
Bongarzone, E.R.7
-
23
-
-
84958020018
-
Autophagy and alpha-synuclein: relevance to Parkinson's disease and related synucleopathies
-
Xilouri M, Brekk OR, Stefanis L. 2016. Autophagy and alpha-synuclein: relevance to Parkinson's disease and related synucleopathies. Mov Disord 31:178–192.
-
(2016)
Mov Disord
, vol.31
, pp. 178-192
-
-
Xilouri, M.1
Brekk, O.R.2
Stefanis, L.3
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