Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and-independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 311, Issue 4, 2016, Pages H904-H912

  Chettimada, Sukrutha ^a,b   Joshi, Sachindra Raj ^a,b   Dhagia, Vidhi ^b   Aiezza, Alessandro ^c   Lincoln, Thomas M ^d   Gupte, Rakhee ^a,b   Miano, Joseph M ^c   Gupte, Sachin A ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b NEW YORK MEDICAL COLLEGE   (United States)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Epigenetics; Metabolism; NADPH redox; Pentose phosphate pathway; Protein kinase G; RNA seq; Vascular smooth muscle phenotype

Indexed keywords

CYCLIC GMP DEPENDENT PROTEIN KINASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; KRUPPEL LIKE FACTOR 4; MICRORNA 1; MICRORNA 143; MYOCARDIN; CONTRACTILE PROTEIN; CYCLIC GMP DEPENDENT PROTEIN KINASE 1; KRUPPEL LIKE FACTOR; MICRORNA; MIRN1 MICRORNA, MOUSE; MIRN143 MICRORNA, MOUSE; NUCLEAR PROTEIN; SERUM RESPONSE FACTOR; TRANSACTIVATOR PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SYSTOLIC BLOOD PRESSURE; UPREGULATION; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; BOVINE; CYTOLOGY; DRUG EFFECTS; GENE SILENCING; GENETICS; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; METABOLISM; POLYMERASE CHAIN REACTION; SMOOTH MUSCLE CELL; TANDEM MASS SPECTROMETRY; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; AORTA; BLOTTING, WESTERN; CATTLE; CHROMATOGRAPHY, LIQUID; CONTRACTILE PROTEINS; CYCLIC GMP-DEPENDENT PROTEIN KINASE TYPE I; CYCLIC GMP-DEPENDENT PROTEIN KINASES; GENE KNOCKDOWN TECHNIQUES; GLUCOSEPHOSPHATE DEHYDROGENASE; IMMUNOPRECIPITATION; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; MICRORNAS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; RATS; SERUM RESPONSE FACTOR; TANDEM MASS SPECTROMETRY; TRANS-ACTIVATORS;

EID: 84990062836     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00335.2016     Document Type: Article

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