Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced cd133+ progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 307, Issue 7, 2014, Pages L545-L556

  Chettimada, Sukrutha ^a   Joshi, Sachindra Raj ^a   Alzoubi, Abdallah ^b   Gebb, Sarah A ^a   McMurtry, Ivan F ^b   Gupte, Rakhee ^a   Gupte, Sachin A ^a,b  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b UNIVERSITY OF SOUTH ALABAMA COLLEGE OF MEDICINE   (United States)

Author keywords

Cell cycle; Cyclin A; Dedifferentiation; HIF; Notch; Pentose phosphate pathway; Pheno type; Phospho histone H3; Pulmonary artery smooth muscle cells; Pulmonary hypertension

Indexed keywords

CD133 ANTIGEN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLYCOPROTEIN; HIF1A PROTEIN, RAT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LEUKOCYTE ANTIGEN; PEPTIDE; PRASTERONE; REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ANTAGONISTS AND INHIBITORS; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; COCULTURE; DRUG EFFECTS; ENZYMOLOGY; HUMAN; HYPERTENSION, PULMONARY; LUNG; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; PATHOLOGY; PHYSIOLOGY; PROTEIN TRANSPORT; PULMONARY ARTERY; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; STEM CELL;

ADMINISTRATION, ORAL; ANIMALS; ANTIGENS, CD; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; COCULTURE TECHNIQUES; DEHYDROEPIANDROSTERONE; GLUCOSEPHOSPHATE DEHYDROGENASE; GLYCOPROTEINS; HUMANS; HYPERTENSION, PULMONARY; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LUNG; MALE; PEPTIDES; PROTEIN TRANSPORT; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STEM CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84907507592     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00303.2013     Document Type: Article

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