Discovery and Function of a General Core Hormetic Stress Response in E. coli Induced by Sublethal Concentrations of Antibiotics

Cell Reports

Volumn 17, Issue 1, 2016, Pages 46-57

  Mathieu, Aurélie ^a   Fleurier, Sébastien ^a   Frénoy, Antoine ^a   Dairou, Julien ^b   Bredeche, Marie Florence ^a   Sanchez Vizuete, Pilar ^a   Song, Xiaohu ^a   Matic, Ivan ^a,c  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c CNRS   (France)

Author keywords

antibiotics; energy metabolism; Escherichia coli; general stress response; hormetic stress response; ppGpp; RpoS; stringent response; sublethal stress; translation

Indexed keywords

AMPICILLIN; CHLORAMPHENICOL; GENTAMICIN; NORFLOXACIN; STREPTOMYCIN; TETRACYCLINE; TRIMETHOPRIM; TRYPTOPHAN; ALKYLATING AGENT; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; CROSS LINKING REAGENT; OXIDIZING AGENT; PROTEOME;

ARTICLE; BACTERIAL CELL; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL METABOLISM; BACTERIAL SURVIVAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; ENERGY METABOLISM; ESCHERICHIA COLI; GENE EXPRESSION; HORMESIS; LETHALITY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUTRIENT AVAILABILITY; PRIORITY JOURNAL; PROMOTER REGION; REGULON; RPOS GENE; TRYPTOPHAN METABOLISM; ADAPTATION; DNA REPAIR; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; PHYSIOLOGICAL STRESS; PROTEIN SYNTHESIS;

ADAPTATION, PHYSIOLOGICAL; ALKYLATING AGENTS; AMPICILLIN; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CROSS-LINKING REAGENTS; DNA REPAIR; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; HORMESIS; MICROBIAL SENSITIVITY TESTS; OXIDANTS; PROTEIN BIOSYNTHESIS; PROTEOME; STRESS, PHYSIOLOGICAL;

EID: 84989952692     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.09.001     Document Type: Article

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