Impact of statins on ALI/ARDS: A meta-analysis

Pulmonary Pharmacology and Therapeutics

Volumn 39, Issue , 2016, Pages 85-91

  Gao, Xia qing ^a,b   Li, Yan fang ^a,b   Jiang, Zhi li ^a,b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF HEART   (China)

Author keywords

ALI; ARDS; Statins

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PLACEBO;

ACUTE LUNG INJURY; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; ARTIFICIAL VENTILATION; COCHRANE LIBRARY; COHORT ANALYSIS; EMBASE; HUMAN; MEDLINE; META ANALYSIS; MORTALITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SENSITIVITY ANALYSIS; SYSTEMATIC REVIEW; PATHOPHYSIOLOGY; RESPIRATORY DISTRESS SYNDROME, ADULT; STATISTICS AND NUMERICAL DATA; TREATMENT OUTCOME;

ACUTE LUNG INJURY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RESPIRATION, ARTIFICIAL; RESPIRATORY DISTRESS SYNDROME, ADULT; TREATMENT OUTCOME;

EID: 84989906381     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2016.06.010     Document Type: Article

References (38)

1. [1] Ochiai, R., Mechanical ventilation of acute respiratory distress syndrome. J. Intensive Care, 3, 2015, 25.
2. [2] Yeo, C.D., Rhee, C.K., Kim, I.K., et al. Protective effect of pravastatin on lipopolysaccharide-induced acute lung injury during neutropenia recovery in mice. Exp. Lung Res. 39:2 (2013), 99–106.
3. [3] Kruger, P., Bailey, M., Bellomo, R., et al. A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis. Am. J. Respir. Crit. Care Med. 187:3 (2013), 743–750.
4. [4] Craig, T.R., Duffy, M.J., Shyamsundar, M., et al. A randomized clinical trial of hydroxymethylglutaryl- coenzyme a reductase inhibition for acute lung injury (The HARP Study). Am. J. Respir. Crit. Care Med. 183:5 (2011), 620–626.
5. [5] McAuley, D.F., Laffey, J.G., O'Kane, C.M., et al. Simvastatin in the acute respiratory distress syndrome. N. Engl. J. Med. 371:18 (2014), 1695–1703.
6. [6] Truwit, J.D., Bernard, G.R., Steingrub, J., et al. Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N. Engl. J. Med. 370:23 (2014), 2191–2200.
7. [7] Moher, D., Liberati, A., Tetzlaff, J., et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Int. J. Surg. Lond. Engl. 8 (2010), 336–341.
8. [8] Moher, D., Jadad, A.R., Tugwell, P., Assessing the quality of randomized controlled trials. Current issues and future directions. Int. J. Technol. Assess. Health Care 12:2 (1996), 195–208.
9. [9] Bonovas, S., Filioussi, K., Tsavaris, N., et al. Use of statins and breast cancer: a meta-analysis of seven randomized clinical trials and nine observational studies. J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol. 23:34 (2005), 8606–8612.
10. [10] Higgins, J.P., Thompson, S.G., Deeks, J.J., et al. Measuring inconsistency in meta-analyses. BMJ 327 (2003), 557–560.
11. [11] Begg, C.B., Mazumdar, M., Operating characteristics of a rank correlation test for publication bias. Biometrics 50 (1994), 1088–1101.
12. [12] Egger, M., Smith, G.D., Schneider, M., et al. Bias in meta-analysis detected by a simple graphical test. BMJ 315 (1997), 629–634.
13. [13] Kor, D.J., Iscimen, R., Yilmaz, M., et al. Statins administration did not influence the progression of lung injury or associated organ failures in a cohort of patients with acute lung injury. Intensive Care Med. 35:6 (2009), 1039–1046.
14. [14] Yadav, H., Lingineni, R.K., Slivinski, E.J., et al. Preoperative statins administration does not protect against early postoperative acute respiratory distress syndrome: a retrospective cohort study. Anesth. Analg. 119:4 (2014), 891–898.
15. [15] The Irish Critical Care Trials Group, Acute lung injury and the acute respiratory distress syndrome in Ireland: a prospective audit of epidemiology and management. Crit. Care, 12(1), 2008, R30.
16. [16] Bruyere, R., Vigneron, C., Prin, S., et al. Impact of prior statins therapy on the outcome of patients with suspected ventilator-associated pneumonia: an observational study. Crit. Care, 18(2), 2014, R83.
17. [17] Bajwa, E.K., Malhotra, C.K., Thompson, B.T., et al. Statins therapy as prevention against development of acute respiratory distress syndrome: an observational study. Crit. Care Med. 40 (2012), 1470–1477.
18. [18] Mansur, A., Steinau, M., Popov, A.F., et al. Impact of statins therapy on mortality in patients with sepsis-associated acute respiratory distress syndrome (ARDS) depends on ARDS severity: a prospective observational cohort study. BMC Med., 13, 2015, 128.
19. [19] Jacobson, J.R., Barnard, J.W., Grigoryev, D.N., et al. Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury. Am. J. Physiol. Lung Cell Mol. Physiol. 288 (2005), L1026–L1032.
20. [20] McDowell, S.A., Ma, Y., Kusano, R., et al. Simvastatin is protective during Staphylococcus aureus pneumonia. Curr. Pharm. Biotechnol. 12 (2011), 1455–1462.
21. [21] Shyamsundar, M., McKeown, S.T., O'Kane, C.M., et al. Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. Am. J. Respir. Crit. Care Med. 179 (2009), 1107–1114.
22. [22] O'Neal, H.R. Jr., Koyama, T., Koehler, E.A., et al. Prehospital statins and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome. Crit. Care Med. 39 (2011), 1343–1350.
23. [23] Vinogradova, Y., Coupland, C., Hippisley-Cox, J., Risk of pneumonia in patients taking statins: population-based nested case-control study. Br. J. General Pract. J. R. Coll. General Pract. 61 (2011), e742–e748.
24. [24] Janda, S., Young, A., Fitzgerald, J.M., et al. The effect of statins on mortality from severe infections and sepsis: a systematic review and meta-analysis. J. Crit. Care, 25(4), 2010, 656 e657-622.
25. [25] Wan, Y.D., Sun, T.W., Kan, Q.C., et al. Effect of statin therapy on mortality from infection and sepsis: a meta-analysis of randomized and observational studies. Crit. Care London Engl., 18(2), 2014, R71.
26. [26] Deshpande, A., Pasupuleti, V., Rothberg, M.B., Statin therapy and mortality from sepsis: a meta-analysis of randomized trials. Am. J. Med. 128:4 (Apr 2015), 410–417 e411.
27. [27] Papazian, L., Roch, A., Charles, P.E., et al. Effect of statin therapy on mortality in patients with ventilator-associated pneumonia: a randomized clinical trial. Jama 310 (2013), 1692–1700.
28. [28] Yang, P., Hong, D.S., Chen, J., et al. Effect of statins on the mortality and mechanical ventilation duration of acute lung injury patients: a meta-analysis of five randomized controlled trials. Int. J. Clin. Pharmacol. Ther. 53:11 (Nov 2015), 923–932.
29. [29] Singla, S., Jacobson, J.R., Statins as a novel therapeutic strategy in acute lung injury. Pulm. Circ. 2:4 (Oct 2012), 397–406.
30. [30] Standiford, T.J., Ward, P.A., Therapeutic targeting of acute lung injury and acute respiratory distress syndrome. Transl. Res. J. Lab. Clin. Med. 167:1 (Jan 2016), 183–191.
31. [31] Yende, S., Milbrandt, E.B., Kellum, J.A., et al. Understanding the potential role of statins in pneumonia and sepsis. Crit. Care Med. 39:8 (Aug 2011), 1871–1878.
32. [32] Chalmers, J.D., Short, P.M., Mandal, P., et al. Statins in community acquired pneumonia: evidence from experimental and clinical studies. Respir. Med. 104:8 (Aug 2010), 1081–1091.
33. [33] Bellia, A., Rizza, S., Galli, A., et al. Early vascular and metabolic effects of rosuvastatin compared with simvastatin in patients with type 2 diabetes. Atherosclerosis 210:1 (May 2010), 199–201.
34. [34] Patel, J.M., Thickett, D.R., Gao, F., et al. Statins for sepsis: distinguishing signal from the noise when designing clinical trials. Am. J. Respir. Crit. Care Med., 188(7), Oct 1 2013, 874.
35. [35] Ou, S.Y., Chu, H., Chao, P.W., et al. Effect of the use of low and high potency statins and sepsis outcomes. Intensive Care Med. 40:10 (Oct 2014), 1509–1517.
36. [36] Frost, F.J., Petersen, H., Tollestrup, K., et al. Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins. Chest 131:4 (Apr 2007), 1006–1012.
37. [37] Ranieri, V.M., Rubenfeld, G.D., Thompson, B.T., et al. Acute respiratory distress syndrome: the Berlin Definition. Jama 307 (2012), 2526–2533.
38. [38] Calfee, C.S., Delucchi, K., Parsons, P.E., et al. Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir. Med. 2 (2014), 611–620.