T-cell clones from Th1, Th17 or Th1/17 lineages and their signature cytokines have different capacity to activate endothelial cells or synoviocytes

Cytokine

Volumn 88, Issue , 2016, Pages 241-250

  Lavocat, Fabien ^a   Maggi, Laura ^b   Annunziato, Francesco ^b   Miossec, Pierre ^a  

^a University of Lyon   (France)

^b UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Endothelial cell; Fibroblast; Inflammation; Synoviocyte; T helper cell

Indexed keywords

CD161 ANTIGEN; CHEMOKINE RECEPTOR CCR6; INTERLEUKIN 17; INTERLEUKIN 6; INTERLEUKIN 8; TUMOR NECROSIS FACTOR; CYTOKINE;

ARTICLE; CD4+ T LYMPHOCYTE; CELL ACTIVATION; CELL INTERACTION; CELL LINEAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; MESENCHYME CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SYNOVIOCYTE; TH1 CELL; TH17 CELL; FEMALE; IMMUNOLOGY; MALE; UMBILICAL VEIN ENDOTHELIAL CELL;

CYTOKINES; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; SYNOVIOCYTES; TH1 CELLS; TH17 CELLS;

EID: 84989211380     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2016.09.019     Document Type: Article

References (35)

1. [1] Harrington, L.E., Hatton, R.D., Mangan, P.R., Turner, H., Murphy, T.L., Murphy, K.M., Weaver, C.T., Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol. 6 (2005), 1123–1132.
2. [2] Cosmi, L., Cimaz, R., Maggi, L., Santarlasci, V., Capone, M., Borriello, F., Frosali, F., Querci, V., Simonini, G., Barra, G., Piccinni, M.P., Liotta, F., De Palma, R., Maggi, E., Romagnani, S., Annunziato, F., Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis. Arthrit. Rheum. 63 (2011), 2504–2515.
3. [3] McInnes, I.B., Schett, G., The pathogenesis of rheumatoid arthritis. N. Engl. J. Med. 365 (2011), 2205–2219.
4. [4] Hashizume, M., Mihara, M., The roles of interleukin-6 in the pathogenesis of rheumatoid arthritis. Arthritis, 2011, 2011, 765624.
5. [5] Nourshargh, S., Alon, R., Leukocyte migration into inflamed tissues. Immunity 41 (2014), 694–707.
6. [6] Van Bezooijen, R.L., Van Der Wee-Pals, L., Papapoulos, S.E., Lowik, C.W., Interleukin 17 synergises with tumour necrosis factor alpha to induce cartilage destruction in vitro. Ann. Rheum. Dis. 61 (2002), 870–876.
7. [7] Bartok, B., Firestein, G.S., Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis. Immunol. Rev. 233 (2010), 233–255.
8. [8] Nagashima, M., Yoshino, S., Aono, H., Takai, M., Sasano, M., Inhibitory effects of anti-rheumatic drugs on vascular endothelial growth factor in cultured rheumatoid synovial cells. Clin. Exp. Immunol. 116 (1999), 360–365.
9. [9] Annunziato, F., Cosmi, L., Santarlasci, V., Maggi, L., Liotta, F., Mazzinghi, B., Parente, E., Fili, L., Ferri, S., Frosali, F., Giudici, F., Romagnani, P., Parronchi, P., Tonelli, F., Maggi, E., Romagnani, S., Phenotypic and functional features of human Th17 cells. J. Exp. Med. 204 (2007), 1849–1861.
10. [10] Cosmi, L., De Palma, R., Santarlasci, V., Maggi, L., Capone, M., Frosali, F., Rodolico, G., Querci, V., Abbate, G., Angeli, R., Berrino, L., Fambrini, M., Caproni, M., Tonelli, F., Lazzeri, E., Parronchi, P., Liotta, F., Maggi, E., Romagnani, S., Annunziato, F., Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J. Exp. Med. 205 (2008), 1903–1916.
11. [11] Leeuwenberg, J.F., von Asmuth, E.J., Jeunhomme, T.M., Buurman, W.A., IFN-gamma regulates the expression of the adhesion molecule ELAM-1 and IL-6 production by human endothelial cells in vitro. J. Immunol. 145 (1990), 2110–2114.
12. [12] Toh, M.L., Kawashima, M., Hot, A., Miossec, P., Role of IL-17 in the Th1 systemic defects in rheumatoid arthritis through selective IL-12Rbeta2 inhibition. Ann. Rheum. Dis. 69 (2010), 1562–1567.
13. [13] Noack, M., Ndongo-Thiam, N., Miossec, P., Interaction among activated lymphocytes and mesenchymal cells through podoplanin is critical for a high IL-17 secretion. Arthrit. Res. Ther., 18, 2016, 148.
14. [14] Hot, A., Lenief, V., Miossec, P., Combination of IL-17 and TNFalpha induces a pro-inflammatory, pro-coagulant and pro-thrombotic phenotype in human endothelial cells. Ann. Rheum. Dis. 71 (2012), 768–776.
15. [15] Hot, A., Miossec, P., Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes. Ann. Rheum. Dis. 70 (2011), 727–732.
16. [16] Lee, S.Y., Yoon, B.Y., Kim, J.I., Heo, Y.M., Woo, Y.J., Park, S.H., Kim, H.Y., Kim, S.I., Cho, M.L., Interleukin-17 increases the expression of Toll-like receptor 3 via the STAT3 pathway in rheumatoid arthritis fibroblast-like synoviocytes. Immunology 141 (2014), 353–361.
17. [17] Moran, E.M., Connolly, M., Gao, W., McCormick, J., Fearon, U., Veale, D.J., Interleukin-17A induction of angiogenesis, cell migration, and cytoskeletal rearrangement. Arthrit. Rheum. 63 (2011), 3263–3273.
18. [18] Alvaro-Gracia, J.M., Zvaifler, N.J., Firestein, G.S., Cytokines in chronic inflammatory arthritis. V. Mutual antagonism between interferon-gamma and tumor necrosis factor-alpha on HLA-DR expression, proliferation, collagenase production, and granulocyte macrophage colony-stimulating factor production by rheumatoid arthritis synoviocytes. J. Clin. Invest. 86 (1990), 1790–1798.
19. [19] Kaplanski, G., Marin, V., Montero-Julian, F., Mantovani, A., Farnarier, C., IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation. Trends Immunol. 24 (2003), 25–29.
20. [20] Roussel, L., Houle, F., Chan, C., Yao, Y., Berube, J., Olivenstein, R., Martin, J.G., Huot, J., Hamid, Q., Ferri, L., Rousseau, S., IL-17 promotes p38 MAPK-dependent endothelial activation enhancing neutrophil recruitment to sites of inflammation. J. Immunol. 184 (2010), 4531–4537.
21. [21] Griffin, G.K., Newton, G., Tarrio, M.L., Bu, D.X., Maganto-Garcia, E., Azcutia, V., Alcaide, P., Grabie, N., Luscinskas, F.W., Croce, K.J., Lichtman, A.H., IL-17 and TNF-alpha sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation. J. Immunol. 188 (2012), 6287–6299.
22. [22] Chabaud, M., Lubberts, E., Joosten, L., van Den Berg, W., Miossec, P., IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis. Arthrit. Res. 3 (2001), 168–177.
23. [23] Nistala, K., Adams, S., Cambrook, H., Ursu, S., Olivito, B., de Jager, W., Evans, J.G., Cimaz, R., Bajaj-Elliott, M., Wedderburn, L.R., Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment. Proc. Natl. Acad. Sci. USA 107 (2010), 14751–14756.
24. [24] Page, G., Miossec, P., RANK and RANKL expression as markers of dendritic cell-T cell interactions in paired samples of rheumatoid synovium and lymph nodes. Arthrit. Rheum. 52 (2005), 2307–2312.
25. [25] Hashizume, M., Hayakawa, N., Mihara, M., IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17. Rheumatology (Oxford) 47 (2008), 1635–1640.
26. [26] Ota, M., Yanagisawa, M., Tachibana, H., Yokota, K., Araki, Y., Sato, K., Mimura, T., A significant induction of neutrophilic chemoattractants but not RANKL in synoviocytes stimulated with interleukin 17. J. Bone Miner. Metab. 33 (2015), 40–47.
27. [27] Rincon, M., Anguita, J., Nakamura, T., Fikrig, E., Flavell, R.A., Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J. Exp. Med. 185 (1997), 461–469.
28. [28] Veldhoen, M., Hocking, R.J., Atkins, C.J., Locksley, R.M., Stockinger, B., TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24 (2006), 179–189.
29. [29] Huber, A.R., Kunkel, S.L., Todd, R.F. 3rd, Weiss, S.J., Regulation of transendothelial neutrophil migration by endogenous interleukin-8. Science 254 (1991), 99–102.
30. [30] Oppenheim, J.J., Zachariae, C.O., Mukaida, N., Matsushima, K., Properties of the novel proinflammatory supergene “intercrine” cytokine family. Annu. Rev. Immunol. 9 (1991), 617–648.
31. [31] Wright, H.L., Moots, R.J., Edwards, S.W., The multifactorial role of neutrophils in rheumatoid arthritis. Nat. Rev. Rheumatol. 10 (2014), 593–601.
32. [32] Eljaafari, A., Tartelin, M.L., Aissaoui, H., Chevrel, G., Osta, B., Lavocat, F., Miossec, P., Bone marrow-derived and synovium-derived mesenchymal cells promote Th17 cell expansion and activation through caspase 1 activation: contribution to the chronicity of rheumatoid arthritis. Arthrit. Rheum. 64 (2012), 2147–2157.
33. [33] Yang, L., Anderson, D.E., Baecher-Allan, C., Hastings, W.D., Bettelli, E., Oukka, M., Kuchroo, V.K., Hafler, D.A., IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature 454 (2008), 350–352.
34. [34] Pickens, S.R., Volin, M.V., Mandelin, A.M. 2nd, Kolls, J.K., Pope, R.M., Shahrara, S., IL-17 contributes to angiogenesis in rheumatoid arthritis. J. Immunol. 184 (2010), 3233–3241.
35. [35] Gottenberg, J.E., Dayer, J.M., Lukas, C., Ducot, B., Chiocchia, G., Cantagrel, A., Saraux, A., Roux-Lombard, P., Mariette, X., Serum IL-6 and IL-21 are associated with markers of B cell activation and structural progression in early rheumatoid arthritis: results from the ESPOIR cohort. Ann. Rheum. Dis. 71 (2012), 1243–1248.