-
2
-
-
67649364114
-
The role of inflammation in insulitis and betacell loss in type 1 diabetes
-
Eizirik DL, Colli ML, Ortis F. The role of inflammation in insulitis and betacell loss in type 1 diabetes. Nat Rev Endocrinol 2009;5:219-226
-
(2009)
Nat Rev Endocrinol
, vol.5
, pp. 219-226
-
-
Eizirik, D.L.1
Colli, M.L.2
Ortis, F.3
-
4
-
-
0033779186
-
Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells
-
Chehadeh W, Kerr-Conte J, Pattou F, et al. Persistent infection of human pancreatic islets by coxsackievirus B is associated with alpha interferon synthesis in beta cells. J Virol 2000;74:10153-10164
-
(2000)
J Virol
, vol.74
, pp. 10153-10164
-
-
Chehadeh, W.1
Kerr-Conte, J.2
Pattou, F.3
-
5
-
-
84962019046
-
Viral infection of engrafted human islets leads to diabetes
-
Gallagher GR, Brehm MA, Finberg RW, et al. Viral infection of engrafted human islets leads to diabetes. Diabetes 2015;64:1358-1369
-
(2015)
Diabetes
, vol.64
, pp. 1358-1369
-
-
Gallagher, G.R.1
Ma, B.2
Finberg, R.W.3
-
6
-
-
85027942576
-
Enteroviruses as causative agents in type 1 diabetes: Loose ends or lost cause?
-
Morgan NG, Richardson SJ. Enteroviruses as causative agents in type 1 diabetes: Loose ends or lost cause? Trends Endocrinol Metab 2014;25:611-619
-
(2014)
Trends Endocrinol Metab
, vol.25
, pp. 611-619
-
-
Morgan, N.G.1
Richardson, S.J.2
-
7
-
-
23844550325
-
Global profiling of coxsackievirusand cytokine-induced gene expression in human pancreatic islets
-
Ylipaasto P, Kutlu B, Rasilainen S, et al. Global profiling of coxsackievirusand cytokine-induced gene expression in human pancreatic islets. Diabetologia 2005;48:1510-1522
-
(2005)
Diabetologia
, vol.48
, pp. 1510-1522
-
-
Ylipaasto, P.1
Kutlu, B.2
Rasilainen, S.3
-
8
-
-
84880336910
-
Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets
-
Lind K, Richardson SJ, Leete P, Morgan NG, Korsgren O, Flodström-Tullberg M. Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets. J Virol 2013;87:7646-7654
-
(2013)
J Virol
, vol.87
, pp. 7646-7654
-
-
Lind, K.1
Richardson, S.J.2
Leete, P.3
Morgan, N.G.4
Korsgren, O.5
Flodström-Tullberg, M.6
-
9
-
-
84859254586
-
The human pancreatic islet transcriptome: Expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines
-
Eizirik DL, Sammeth M, Bouckenooghe T, et al. The human pancreatic islet transcriptome: Expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines. PLoS Genet 2012;8:e1002552
-
(2012)
PLoS Genet
, vol.8
, pp. e1002552
-
-
Eizirik, D.L.1
Sammeth, M.2
Bouckenooghe, T.3
-
10
-
-
0023520177
-
Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus
-
Foulis AK, Farquharson MA, Meager A. Immunoreactive alpha-interferon in insulin-secreting beta cells in type 1 diabetes mellitus. Lancet 1987;2:1423-1427
-
(1987)
Lancet
, vol.2
, pp. 1423-1427
-
-
Foulis, A.K.1
Ma, F.2
Meager, A.3
-
11
-
-
34247627376
-
Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients
-
Dotta F, Censini S, van Halteren AG, et al. Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. Proc Natl Acad Sci U S A 2007;104:5115-5120
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5115-5120
-
-
Dotta, F.1
Censini, S.2
Van Halteren, A.G.3
-
12
-
-
79251618259
-
Immunopathology of the human pancreas in type-I diabetes
-
Richardson SJ, Willcox A, Bone AJ, Morgan NG, Foulis AK. Immunopathology of the human pancreas in type-I diabetes. Semin Immunopathol 2011;33:9-21
-
(2011)
Semin Immunopathol
, vol.33
, pp. 9-21
-
-
Richardson, S.J.1
Willcox, A.2
Bone, A.J.3
Morgan, N.G.4
Foulis, A.K.5
-
13
-
-
74549199886
-
Islet inflammation and CXCL10 in recent-onset type 1 diabetes
-
Roep BO, Kleijwegt FS, van Halteren AG, et al. Islet inflammation and CXCL10 in recent-onset type 1 diabetes. Clin Exp Immunol 2010;159:338-343
-
(2010)
Clin Exp Immunol
, vol.159
, pp. 338-343
-
-
Roep, B.O.1
Kleijwegt, F.S.2
Van Halteren, A.G.3
-
14
-
-
70349651422
-
Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: A mechanism of accelerated b-cell failure in fulminant type 1 diabetes
-
Tanaka S, Nishida Y, Aida K, et al. Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: A mechanism of accelerated b-cell failure in fulminant type 1 diabetes. Diabetes 2009;58:2285-2291
-
(2009)
Diabetes
, vol.58
, pp. 2285-2291
-
-
Tanaka, S.1
Nishida, Y.2
Aida, K.3
-
15
-
-
0028278373
-
Pancreas in recent onset insulindependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor v beta usage, and cytokine profile
-
Somoza N, Vargas F, Roura-Mir C, et al. Pancreas in recent onset insulindependent diabetes mellitus. Changes in HLA, adhesion molecules and autoantigens, restricted T cell receptor V beta usage, and cytokine profile. J Immunol 1994;153:1360-1377
-
(1994)
J Immunol
, vol.153
, pp. 1360-1377
-
-
Somoza, N.1
Vargas, F.2
Roura-Mir, C.3
-
16
-
-
0029036567
-
Interferon expression in the pancreases of patients with type i diabetes
-
Huang X, Yuang J, Goddard A, et al. Interferon expression in the pancreases of patients with type I diabetes. Diabetes 1995;44:658-664
-
(1995)
Diabetes
, vol.44
, pp. 658-664
-
-
Huang, X.1
Yuang, J.2
Goddard, A.3
-
17
-
-
70749093491
-
Gene expression profiles for the human pancreas and purified islets in type 1 diabetes: New findings at clinical onset and in long-standing diabetes
-
Planas R, Carrillo J, Sanchez A, et al. Gene expression profiles for the human pancreas and purified islets in type 1 diabetes: new findings at clinical onset and in long-standing diabetes. Clin Exp Immunol 2010;159:23-44
-
(2010)
Clin Exp Immunol
, vol.159
, pp. 23-44
-
-
Planas, R.1
Carrillo, J.2
Sanchez, A.3
-
18
-
-
84896080372
-
Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: Experiences from the DiViD study
-
Krogvold L, Edwin B, Buanes T, et al. Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: Experiences from the DiViD study. Diabetologia 2014;57:841-843
-
(2014)
Diabetologia
, vol.57
, pp. 841-843
-
-
Krogvold, L.1
Edwin, B.2
Buanes, T.3
-
19
-
-
84957437395
-
Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes
-
Krogvold L, Wiberg A, Edwin B, et al. Insulitis and characterisation of infiltrating T cells in surgical pancreatic tail resections from patients at onset of type 1 diabetes. Diabetologia 2016;59:492-501
-
(2016)
Diabetologia
, vol.59
, pp. 492-501
-
-
Krogvold, L.1
Wiberg, A.2
Edwin, B.3
-
20
-
-
84962097619
-
Function of isolated pancreatic islets from patients at onset of type 1 diabetes: Insulin secretion can be restored after some days in a nondiabetogenic environment in vitro: Results from the DiViD Study
-
Krogvold L, Skog O, Sundström G, et al. Function of isolated pancreatic islets from patients at onset of type 1 diabetes: Insulin secretion can be restored after some days in a nondiabetogenic environment in vitro: Results from the DiViD Study. Diabetes 2015;64:2506-2512
-
(2015)
Diabetes
, vol.64
, pp. 2506-2512
-
-
Krogvold, L.1
Skog, O.2
Sundström, G.3
-
21
-
-
84933544989
-
Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes
-
Krogvold L, Edwin B, Buanes T, et al. Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes. Diabetes 2015;64:1682-1687
-
(2015)
Diabetes
, vol.64
, pp. 1682-1687
-
-
Krogvold, L.1
Edwin, B.2
Buanes, T.3
-
22
-
-
84924077681
-
Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans
-
Skog O, Ingvast S, Korsgren O. Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans. J Clin Virol 2014;61:242-247
-
(2014)
J Clin Virol
, vol.61
, pp. 242-247
-
-
Skog, O.1
Ingvast, S.2
Korsgren, O.3
-
23
-
-
34447617193
-
Induction of the chemokine interferongamma-inducible protein-10 in human pancreatic islets during enterovirus infection
-
Berg AK, Korsgren O, Frisk G. Induction of the chemokine interferongamma-inducible protein-10 in human pancreatic islets during enterovirus infection. Diabetologia 2006;49:2697-2703
-
(2006)
Diabetologia
, vol.49
, pp. 2697-2703
-
-
Berg, A.K.1
Korsgren, O.2
Frisk, G.3
-
24
-
-
58749093419
-
CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling
-
Schulthess FT, Paroni F, Sauter NS, et al. CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling. Cell Metab 2009;9:125-139
-
(2009)
Cell Metab
, vol.9
, pp. 125-139
-
-
Schulthess, F.T.1
Paroni, F.2
Sauter, N.S.3
-
25
-
-
15744395579
-
Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans
-
Olsson A, Johansson U, Korsgren O, Frisk G. Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans. Biochem Biophys Res Commun 2005;330:571-576
-
(2005)
Biochem Biophys Res Commun
, vol.330
, pp. 571-576
-
-
Olsson, A.1
Johansson, U.2
Korsgren, O.3
Frisk, G.4
-
26
-
-
84864389686
-
Cytokine and chemokine production by human pancreatic islets upon enterovirus infection
-
Schulte BM, Lanke KH, Piganelli JD, et al. Cytokine and chemokine production by human pancreatic islets upon enterovirus infection. Diabetes 2012;61: 2030-2036
-
(2012)
Diabetes
, vol.61
, pp. 2030-2036
-
-
Schulte, B.M.1
Lanke, K.H.2
Piganelli, J.D.3
-
27
-
-
57349108800
-
Guanylate binding protein-1 inhibits spreading and migration of endothelial cells through induction of integrin alpha4 expression
-
Weinländer K, Naschberger E, Lehmann MH, et al. Guanylate binding protein-1 inhibits spreading and migration of endothelial cells through induction of integrin alpha4 expression. FASEB J 2008;22:4168-4178
-
(2008)
FASEB J
, vol.22
, pp. 4168-4178
-
-
Weinländer, K.1
Naschberger, E.2
Lehmann, M.H.3
-
28
-
-
79959460585
-
Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases
-
Hammon M, Herrmann M, Bleiziffer O, et al. Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases. J Cell Mol Med 2011;15:1582-1592
-
(2011)
J Cell Mol Med
, vol.15
, pp. 1582-1592
-
-
Hammon, M.1
Herrmann, M.2
Bleiziffer, O.3
-
29
-
-
84901842522
-
Infection of human islets of Langerhans with two strains of Coxsackie B virus serotype 1: Assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway
-
Anagandula M, Richardson SJ, Oberste MS, et al. Infection of human islets of Langerhans with two strains of Coxsackie B virus serotype 1: Assessment of virus replication, degree of cell death and induction of genes involved in the innate immunity pathway. J Med Virol 2014;86:1402-1411
-
(2014)
J Med Virol
, vol.86
, pp. 1402-1411
-
-
Anagandula, M.1
Richardson, S.J.2
Oberste, M.S.3
-
30
-
-
84857737745
-
Immunology in the clinic review series; Focus on type 1 diabetes and viruses: The innate immune response to enteroviruses and its possible role in regulating type 1 diabetes
-
Lind K, Hühn MH, Flodström-Tullberg M. Immunology in the clinic review series; focus on type 1 diabetes and viruses: The innate immune response to enteroviruses and its possible role in regulating type 1 diabetes. Clin Exp Immunol 2012;168:30-38
-
(2012)
Clin Exp Immunol
, vol.168
, pp. 30-38
-
-
Lind, K.1
Hühn, M.H.2
Flodström-Tullberg, M.3
-
31
-
-
0036222240
-
Target cell defense prevents the development of diabetes after viral infection
-
Flodström M, Maday A, Balakrishna D, Cleary MM, Yoshimura A, Sarvetnick N. Target cell defense prevents the development of diabetes after viral infection. Nat Immunol 2002;3:373-382
-
(2002)
Nat Immunol
, vol.3
, pp. 373-382
-
-
Flodström, M.1
Maday, A.2
Balakrishna, D.3
Cleary, M.M.4
Yoshimura, A.5
Sarvetnick, N.6
-
32
-
-
84926683121
-
Reduced Tyk2 gene expression in β-Cells due to natural mutation determines susceptibility to virus-induced diabetes
-
Izumi K, Mine K, Inoue Y, et al. Reduced Tyk2 gene expression in β-Cells due to natural mutation determines susceptibility to virus-induced diabetes. Nat Commun 2015;6:6748
-
(2015)
Nat Commun
, vol.6
, pp. 6748
-
-
Izumi, K.1
Mine, K.2
Inoue, Y.3
-
33
-
-
79951523016
-
Modulation of innate immunity in human pancreatic islets infected with enterovirus in vitro
-
Skog O, Korsgren O, Frisk G. Modulation of innate immunity in human pancreatic islets infected with enterovirus in vitro. J Med Virol 2011;83:658-664
-
(2011)
J Med Virol
, vol.83
, pp. 658-664
-
-
Skog, O.1
Korsgren, O.2
Frisk, G.3
-
34
-
-
84939974788
-
Analysis of peri-islet CD45-positive leucocytic infiltrates in long-standing type 1 diabetic patients
-
Reddy S, Zeng N, Al-Diery H, et al. Analysis of peri-islet CD45-positive leucocytic infiltrates in long-standing type 1 diabetic patients. Diabetologia 2015; 58:1024-1035
-
(2015)
Diabetologia
, vol.58
, pp. 1024-1035
-
-
Reddy, S.1
Zeng, N.2
Al-Diery, H.3
|