Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases

Journal of Cellular and Molecular Medicine

Volumn 15, Issue 7, 2011, Pages 1582-1592

  Hammon, Matthias ^a   Herrmann, Martin ^a   Bleiziffer, Oliver ^a   Pryymachuk, Galyna ^a   Andreoli, Laura ^b   Munoz, Luis E ^a   Amann, Kerstin U ^a   Mondini, Michele ^c   Gariglio, Marisa ^c   Airó, Paolo ^b   Schellerer, Vera S ^a   Hatzopoulos, Antonis K ^d   Horch, Raymund E ^a   Kneser, Ulrich ^a   Stürzl, Michael ^a   Naschberger, Elisabeth ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b SPEDALI CIVILI   (Italy)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endothelial progenitor cells; Guanylate binding protein 1; Inflammation; Rheumatic autoimmune disorders; Rheumatoid arthritis; Systemic lupus erythematosus; Systemic sclerosis

Indexed keywords

GBP1 PROTEIN, HUMAN; GUANINE NUCLEOTIDE BINDING PROTEIN;

ADULT; AGED; ANIMAL; ARTICLE; AUTOIMMUNE DISEASE; CELL DIFFERENTIATION; CELL MOTION; CHRONIC DISEASE; CYTOLOGY; ENDOTHELIUM CELL; FEMALE; HUMAN; IMMUNOLOGY; INFLAMMATION; METABOLISM; MIDDLE AGED; MOUSE; PATHOLOGY; RAT; STEM CELL; VASCULAR ENDOTHELIUM;

ADULT; AGED; ANIMALS; AUTOIMMUNE DISEASES; CELL DIFFERENTIATION; CELL MOVEMENT; CHRONIC DISEASE; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; GTP-BINDING PROTEINS; HUMANS; INFLAMMATION; MICE; MIDDLE AGED; RATS; STEM CELLS;

RATTUS;

EID: 79959460585     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1582-4934.2010.01146.x     Document Type: Article

References (46)

1. Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med. 2000; 6: 389-95.
2. Carmeliet P. Angiogenesis in health and disease. Nat Med. 2003; 9: 653-60.
3. Kilarski WW, Samolov B, Petersson L, et al Biomechanical regulation of blood vessel growth during tissue vascularization. Nat Med. 2009; 15: 657-64.
4. Risau W, Sariola H, Zerwes HG, et al Vasculogenesis and angiogenesis in embryonic-stem-cell-derived embryoid bodies. Development. 1988; 102: 471-8.
5. Ingram DA, Caplice NM, Yoder MC. Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood. 2005; 106: 1525-31.
6. Asahara T, Murohara T, Sullivan A, et al Isolation of putative progenitor endothelial cells for angiogenesis. Science. 1997; 275: 964-7.
7. Asahara T, Takahashi T, Masuda H, et al VEGF contributes to postnatal neovascularization by mobilizing bone marrow-derived endothelial progenitor cells. EMBO J. 1999; 18: 3964-72.
8. Takahashi T, Kalka C, Masuda H, et al Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med. 1999; 5: 434-8.
9. Shaked Y, Ciarrocchi A, Franco M, et al Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors. Science. 2006; 313: 1785-7.
10. Rafii S, Lyden D, Benezra R, et al Vascular and haematopoietic stem cells: novel targets for anti-angiogenesis therapy Nat Rev Cancer. 2002; 2: 826-35.
11. Kuwana M, Kaburaki J, Okazaki Y, et al Increase in circulating endothelial precursors by atorvastatin in patients with systemic sclerosis. Arthritis Rheum. 2006; 54: 1946-51.
12. Westerweel PE, Luijten RK, Hoefer IE, et al Haematopoietic and endothelial progenitor cells are deficient in quiescent systemic lupus erythematosus. Ann Rheum Dis. 2007; 66: 865-70.
13. Herbrig K, Haensel S, Oelschlaegel U, et al Endothelial dysfunction in patients with rheumatoid arthritis is associated with a reduced number and impaired function of endothelial progenitor cells. Ann Rheum Dis. 2006; 65: 157-63.
14. Grisar J, Aletaha D, Steiner CW, et al Depletion of endothelial progenitor cells in the peripheral blood of patients with rheumatoid arthritis. Circulation. 2005; 111: 204-11.
15. Avouac J, Uzan G, Kahan A, et al Endothelial progenitor cells and rheumatic disorders. Joint Bone Spine. 2008; 75: 131-7.
16. Banchereau J, Pascual V. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. Immunity. 2006; 25: 383-92.
17. Karonitsch T, Feierl E, Steiner CW, et al Activation of the interferon-gamma signaling pathway in systemic lupus erythematosus peripheral blood mononuclear cells. Arthritis Rheum. 2009; 60: 1463-71.
18. Brennan FM, McInnes IB. Evidence that cytokines play a role in rheumatoid arthritis. J Clin Invest. 2008; 118: 3537-45.
19. Ablin JN, Boguslavski V, Aloush V, et al Effect of anti-TNFalpha treatment on circulating endothelial progenitor cells (EPCs) in rheumatoid arthritis. Life Sci. 2006; 79: 2364-9.
20. Prakash B, Praefcke GJ, Renault L, et al Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. Nature. 2000; 403: 567-71.
21. Prakash B, Renault L, Praefcke GJ, et al Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. EMBO J. 2000; 19: 4555-64.
22. Schwemmle M, Staeheli P. The interferon-induced 67-kDa guanylate-binding protein (hGBP1) is a GTPase that converts GTP to GMP. J Biol Chem. 1994; 269: 11299-305.
23. Naschberger E, Bauer M, Stürzl M. Human guanylate binding protein-1 (hGBP-1) characterizes and establishes a non-angiogenic endothelial cell activation phenotype in inflammatory diseases. Adv Enzyme Regul. 2005; 45: 215-27.
24. Tripal P, Bauer M, Naschberger E, et al Unique features of different members of the human guanylate-binding protein family. J Interferon Cytokine Res. 2007; 27: 44-52.
25. Lubeseder-Martellato C, Guenzi E, Jörg A, et al Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases. Am J Pathol. 2002; 161: 1749-59.
26. Guenzi E, Töpolt K, Cornali E, et al The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines. EMBO J. 2001; 20: 5568-77.
27. Guenzi E, Töpolt K, Lubeseder-Martellato C, et al The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression. EMBO J. 2003; 22: 3772-82.
28. Weinländer K, Naschberger E, Lehmann MH, et al Guanylate binding protein-1 inhibits spreading and migration of endothelial cells through induction of integrin alpha4 expression. FASEB J. 2008; 22: 4168-78.
29. Naschberger E, Croner RS, Merkel S, et al Angiostatic immune reaction in colorectal carcinoma: impact on survival and perspectives for antiangiogenic therapy. Int J Cancer. 2008; 123: 2120-9.
30. Naschberger E, Lubeseder-Martellato C, Meyer N, et al Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis. Am J Pathol. 2006; 169: 1088-99.
31. Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1997; 40: 1725.
32. Arnett FC, Edworthy SM, Bloch DA, et al The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988; 31: 315-24.
33. LeRoy EC, Black C, Fleischmajer R, et al Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol. 1988; 15: 202-5.
34. Hatzopoulos AK, Folkman J, Vasile E, et al Isolation and characterization of endothelial progenitor cells from mouse embryos. Development. 1998; 125: 1457-68.
35. Bleiziffer O, Horch RE, Hammon M, et al T17b murine embryonal endothelial progenitor cells can be induced towards both proliferation and differentiation in a fibrin matrix. J Cell Mol Med. 2009; 13: 926-35.
36. Vajkoczy P, Blum S, Lamparter M, et al Multistep nature of microvascular recruitment of ex vivo-expanded embryonic endothelial progenitor cells during tumor angiogenesis. J Exp Med. 2003; 197: 1755-65.
37. Schellerer VS, Croner RS, Weinländer K, et al Endothelial cells of human colorectal cancer and healthy colon reveal phenotypic differences in culture. Lab Invest. 2007; 87: 1159-70.
38. Arkudas A, Tjiawi J, Saumweber A, et al Evaluation of blood vessel ingrowth in fibrin gel subject to type and concentration of growth factors. J Cell Mol Med. 2009; 13: 2864-74.
39. Polykandriotis E, Euler S, Arkudas A, et al Regression and persistence: remodelling in a tissue engineered axial vascular assembly. J Cell Mol Med. 2009. DOI.
40. Arkudas A, Tjiawi J, Bleiziffer O, et al Fibrin gel-immobilized VEGF and bFGF efficiently stimulate angiogenesis in the AV loop model. Mol Med. 2007; 13: 480-7.
41. Decaris ML, Lee CI, Yoder MC, et al Influence of the oxygen microenvironment on the proangiogenic potential of human endothelial colony forming cells. Angiogenesis. 2009; 12: 303-11.
42. Belmont HM, Buyon J, Giorno R, et al Up-regulation of endothelial cell adhesion molecules characterizes disease activity in systemic lupus erythematosus. The Shwartzman phenomenon revisited. Arthritis Rheum. 1994; 37: 376-83.
43. Yusuf-Makagiansar H, Anderson ME, Yakovleva TV, et al Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases. Med Res Rev. 2002; 22: 146-67.
44. Mondini M, Vidali M, De Andrea M, et al A novel autoantigen to differentiate limited cutaneous systemic sclerosis from diffuse cutaneous systemic sclerosis: the interferon-inducible gene IFI16. Arthritis Rheum. 2006; 54: 3939-44.
45. Caposio P, Gugliesi F, Zannetti C, et al A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells. J Biol Chem. 2007; 282: 33515-29.
46. Cornali E, Zietz C, Benelli R, et al Vascular endothelial growth factor regulates angiogenesis and vascular permeability in Kaposi's sarcoma. Am J Pathol. 1996; 149: 1851-69.