-
1
-
-
34250214880
-
Myeloid lineage commitment from the hematopoietic stem cell
-
10.1016/j.immuni.2007.06.004 1:CAS:528:DC%2BD2sXntlKnuro%3D 17582345
-
Iwasaki H, Akashi K (2007) Myeloid lineage commitment from the hematopoietic stem cell. Immunity 26:726-740
-
(2007)
Immunity
, vol.26
, pp. 726-740
-
-
Iwasaki, H.1
Akashi, K.2
-
2
-
-
39349096526
-
Hematopoiesis: An evolving paradigm for stem cell biology
-
10.1016/j.cell.2008.01.025 1:CAS:528:DC%2BD1cXivVagtrk%3D 18295580
-
Orkin SH, Zon LI (2008) Hematopoiesis: an evolving paradigm for stem cell biology. Cell 132:631-644
-
(2008)
Cell
, vol.132
, pp. 631-644
-
-
Orkin, S.H.1
Zon, L.I.2
-
3
-
-
67349205004
-
Multilevel targeting of hematopoietic stem cell self-renewal, differentiation and apoptosis for leukemia therapy
-
10.1016/j.pharmthera.2009.03.001 1:CAS:528:DC%2BD1MXmsVSgtb4%3D 19306896
-
Tsiftsoglou AS, Bonovolias ID, Tsiftsoglou SA (2009) Multilevel targeting of hematopoietic stem cell self-renewal, differentiation and apoptosis for leukemia therapy. Pharmacol Ther 122:264-280
-
(2009)
Pharmacol Ther
, vol.122
, pp. 264-280
-
-
Tsiftsoglou, A.S.1
Bonovolias, I.D.2
Tsiftsoglou, S.A.3
-
4
-
-
58549117664
-
Transcriptional regulatory networks in haematopoiesis
-
10.1016/j.gde.2008.09.001 1:CAS:528:DC%2BD1MXhtFCjsr4%3D 18838119
-
Miranda-Saavedra D, Gottgens B (2008) Transcriptional regulatory networks in haematopoiesis. Curr Opin Genet Dev 18:530-535
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 530-535
-
-
Miranda-Saavedra, D.1
Gottgens, B.2
-
5
-
-
35348903151
-
Transcriptional control of erythropoiesis: Emerging mechanisms and principles
-
10.1038/sj.onc.1210761 1:CAS:528:DC%2BD2sXhtFKhsLnL 17934485
-
Kim SI, Bresnick EH (2007) Transcriptional control of erythropoiesis: emerging mechanisms and principles. Oncogene 26:6777-6794
-
(2007)
Oncogene
, vol.26
, pp. 6777-6794
-
-
Kim, S.I.1
Bresnick, E.H.2
-
6
-
-
33748171960
-
The c-Myc target gene network
-
10.1016/j.semcancer.2006.07.014 1:CAS:528:DC%2BD28XpsVWksb8%3D 16904903
-
Dang CV, O'Donnell KA, Zeller KI, Nguyen T, Osthus RC et al (2006) The c-Myc target gene network. Semin Cancer Biol 16:253-264
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 253-264
-
-
Dang, C.V.1
O'Donnell, K.A.2
Zeller, K.I.3
Nguyen, T.4
Osthus, R.C.5
-
7
-
-
0036192061
-
The myc oncogene: MarvelouslY complex
-
10.1016/S0065-230X(02)84004-0 1:CAS:528:DC%2BD38XlsVWqtrw%3D 11885563
-
Oster SK, Ho CS, Soucie EL, Penn LZ (2002) The myc oncogene: marvelouslY complex. Adv Cancer Res 84:81-154
-
(2002)
Adv Cancer Res
, vol.84
, pp. 81-154
-
-
Oster, S.K.1
Ho, C.S.2
Soucie, E.L.3
Penn, L.Z.4
-
8
-
-
54349087788
-
Myc's broad reach
-
10.1101/gad.1712408 1:CAS:528:DC%2BD1cXht12ht7zE 18923074
-
Eilers M, Eisenman RN (2008) Myc's broad reach. Genes Dev 22:2755-2766
-
(2008)
Genes Dev
, vol.22
, pp. 2755-2766
-
-
Eilers, M.1
Eisenman, R.N.2
-
9
-
-
65949119311
-
Inhibition of cell differentiation: A critical mechanism for MYC-mediated carcinogenesis?
-
10.4161/cc.8.8.8126 1:CAS:528:DC%2BD1MXlvFWitrY%3D 19282668
-
Leon J, Ferrandiz N, Acosta JC, Delgado MD (2009) Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis? Cell Cycle 8:1148-1157
-
(2009)
Cell Cycle
, vol.8
, pp. 1148-1157
-
-
Leon, J.1
Ferrandiz, N.2
Acosta, J.C.3
Delgado, M.D.4
-
10
-
-
0033551374
-
MYC oncogenes and human neoplastic disease
-
10.1038/sj.onc.1202746 1:CAS:528:DyaK1MXjs12qtLg%3D 10378696
-
Nesbit CE, Tersak JM, Prochownik EV (1999) MYC oncogenes and human neoplastic disease. Oncogene 18:3004-3016
-
(1999)
Oncogene
, vol.18
, pp. 3004-3016
-
-
Nesbit, C.E.1
Tersak, J.M.2
Prochownik, E.V.3
-
11
-
-
33748192942
-
The Myc oncoprotein as a therapeutic target for human cancer
-
10.1016/j.semcancer.2006.07.015 1:CAS:528:DC%2BD28XpsVWksbk%3D 16934487
-
Vita M, Henriksson M (2006) The Myc oncoprotein as a therapeutic target for human cancer. Semin Cancer Biol 16:318-330
-
(2006)
Semin Cancer Biol
, vol.16
, pp. 318-330
-
-
Vita, M.1
Henriksson, M.2
-
12
-
-
0021697881
-
The molecular genetics of cellular oncogenes
-
10.1146/annurev.ge.18.120184.003005 1:CAS:528:DyaL2MXktVOnsw%3D%3D 6397126
-
Varmus HE (1984) The molecular genetics of cellular oncogenes. Annu Rev Genet 18:553-612
-
(1984)
Annu Rev Genet
, vol.18
, pp. 553-612
-
-
Varmus, H.E.1
-
13
-
-
0037441895
-
Cell cycle deregulation in B-cell lymphomas
-
10.1182/blood-2002-07-2009 1:CAS:528:DC%2BD3sXht1agt7c%3D 12393483
-
Sanchez-Beato M, Sanchez-Aguilera A, Piris MA (2003) Cell cycle deregulation in B-cell lymphomas. Blood 101:1220-1235
-
(2003)
Blood
, vol.101
, pp. 1220-1235
-
-
Sanchez-Beato, M.1
Sanchez-Aguilera, A.2
Piris, M.A.3
-
14
-
-
79952830167
-
Myc roles in hematopoiesis and leukemia
-
10.1177/1947601910377495 1:CAS:528:DC%2BC3cXhtFyisLfJ 21779460
-
Delgado MD, Leon J (2010) Myc roles in hematopoiesis and leukemia. Genes Cancer 1:605-616
-
(2010)
Genes Cancer
, vol.1
, pp. 605-616
-
-
Delgado, M.D.1
Leon, J.2
-
15
-
-
0018773455
-
DNA and RNA from uninfected vertebrate cells contain nucleotide sequences related to the putative transforming gene of avian myelocytomatosis virus
-
1:CAS:528:DyaE1MXlt1Wru7w%3D 225569
-
Sheiness D, Bishop JM (1979) DNA and RNA from uninfected vertebrate cells contain nucleotide sequences related to the putative transforming gene of avian myelocytomatosis virus. J Virol 31:514-521
-
(1979)
J Virol
, vol.31
, pp. 514-521
-
-
Sheiness, D.1
Bishop, J.M.2
-
16
-
-
0022468529
-
Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment
-
10.1038/320760a0 1:CAS:528:DyaL28Xit1aktL4%3D 3458027
-
Coppola JA, Cole MD (1986) Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment. Nature 320:760-763
-
(1986)
Nature
, vol.320
, pp. 760-763
-
-
Coppola, J.A.1
Cole, M.D.2
-
17
-
-
0022475349
-
Deregulated expression of c-myc by murine erythroleukaemia cells prevents differentiation
-
10.1038/322848a0 1:CAS:528:DyaL28Xls1Kit7s%3D 3528863
-
Prochownik EV, Kukowska J (1986) Deregulated expression of c-myc by murine erythroleukaemia cells prevents differentiation. Nature 322:848-850
-
(1986)
Nature
, vol.322
, pp. 848-850
-
-
Prochownik, E.V.1
Kukowska, J.2
-
18
-
-
0022500806
-
Expression of a transfected human c-myc oncogene inhibits differentiation of a mouse erythroleukaemia cell line
-
10.1038/322748a0 1:CAS:528:DyaL28XlvVGjtLY%3D 3528861
-
Dmitrovsky E, Kuehl WM, Hollis GF, Kirsch IR, Bender TP et al (1986) Expression of a transfected human c-myc oncogene inhibits differentiation of a mouse erythroleukaemia cell line. Nature 322:748-750
-
(1986)
Nature
, vol.322
, pp. 748-750
-
-
Dmitrovsky, E.1
Kuehl, W.M.2
Hollis, G.F.3
Kirsch, I.R.4
Bender, T.P.5
-
19
-
-
0029062587
-
Differential regulation of Max and role of c-Myc during erythroid and myelomonocytic differentiation of K562 cells
-
1:CAS:528:DyaK2MXlsVaqs7s%3D 7731722
-
Delgado MD, Lerga A, Canelles M, Gomez-Casares MT, Leon J (1995) Differential regulation of Max and role of c-Myc during erythroid and myelomonocytic differentiation of K562 cells. Oncogene 10:1659-1665
-
(1995)
Oncogene
, vol.10
, pp. 1659-1665
-
-
Delgado, M.D.1
Lerga, A.2
Canelles, M.3
Gomez-Casares, M.T.4
Leon, J.5
-
20
-
-
57349150176
-
Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest
-
10.1128/MCB.00752-08 1:CAS:528:DC%2BD1cXhsV2mtLjP 18838534
-
Acosta JC, Ferrandiz N, Bretones G, Torrano V, Blanco R et al (2008) Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest. Mol Cell Biol 28:7286-7295
-
(2008)
Mol Cell Biol
, vol.28
, pp. 7286-7295
-
-
Acosta, J.C.1
Ferrandiz, N.2
Bretones, G.3
Torrano, V.4
Blanco, R.5
-
21
-
-
0030860849
-
Cell-cycle progression is not essential for c-Myc to block differentiation
-
10.1038/sj.onc.1201124 1:CAS:528:DyaK2sXktF2ntLk%3D 9190900
-
Ryan KM, Birnie GD (1997) Cell-cycle progression is not essential for c-Myc to block differentiation. Oncogene 14:2835-2843
-
(1997)
Oncogene
, vol.14
, pp. 2835-2843
-
-
Ryan, K.M.1
Birnie, G.D.2
-
22
-
-
0027504794
-
Down-regulation of c-myc gene is not obligatory for growth inhibition and differentiation of human myeloid leukemia cells
-
1:STN:280:DyaK2c%2FkvVahtA%3D%3D 8231250
-
Gomez-Casares MT, Delgado MD, Lerga A, Crespo P, Quincoces AF et al (1993) Down-regulation of c-myc gene is not obligatory for growth inhibition and differentiation of human myeloid leukemia cells. Leukemia 7:1824-1833
-
(1993)
Leukemia
, vol.7
, pp. 1824-1833
-
-
Gomez-Casares, M.T.1
Delgado, M.D.2
Lerga, A.3
Crespo, P.4
Quincoces, A.F.5
-
23
-
-
0033153098
-
Posttranslational regulation of Myc function in response to phorbol ester/interferon-gamma-induced differentiation of v-Myc-transformed U-937 monoblasts
-
1:CAS:528:DyaK1MXjsVOnt70%3D 10339499
-
Bahram F, Wu S, Oberg F, Luscher B, Larsson LG (1999) Posttranslational regulation of Myc function in response to phorbol ester/interferon-gamma-induced differentiation of v-Myc-transformed U-937 monoblasts. Blood 93:3900-3912
-
(1999)
Blood
, vol.93
, pp. 3900-3912
-
-
Bahram, F.1
Wu, S.2
Oberg, F.3
Luscher, B.4
Larsson, L.G.5
-
24
-
-
84856185118
-
E-box-independent regulation of transcription and differentiation by MYC
-
10.1038/ncb2355 1:CAS:528:DC%2BC3MXhtlGks7nJ 22020439
-
Uribesalgo I, Buschbeck M, Gutierrez A, Teichmann S, Demajo S et al (2011) E-box-independent regulation of transcription and differentiation by MYC. Nat Cell Biol 13:1443-1449
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1443-1449
-
-
Uribesalgo, I.1
Buschbeck, M.2
Gutierrez, A.3
Teichmann, S.4
Demajo, S.5
-
25
-
-
70349246859
-
C-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors
-
10.1182/blood-2009-01-197947 1:CAS:528:DC%2BD1MXhtFKksLrP 19372257
-
Guo Y, Niu C, Breslin P, Tang M, Zhang S et al (2009) c-Myc-mediated control of cell fate in megakaryocyte-erythrocyte progenitors. Blood 114:2097-2106
-
(2009)
Blood
, vol.114
, pp. 2097-2106
-
-
Guo, Y.1
Niu, C.2
Breslin, P.3
Tang, M.4
Zhang, S.5
-
26
-
-
0029836239
-
Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization
-
10.1074/jbc.271.38.22976 1:CAS:528:DyaK28XlvVCitb4%3D 8798484
-
Thompson A, Zhang Y, Kamen D, Jackson CW, Cardiff RD et al (1996) Deregulated expression of c-myc in megakaryocytes of transgenic mice increases megakaryopoiesis and decreases polyploidization. J Biol Chem 271:22976-22982
-
(1996)
J Biol Chem
, vol.271
, pp. 22976-22982
-
-
Thompson, A.1
Zhang, Y.2
Kamen, D.3
Jackson, C.W.4
Cardiff, R.D.5
-
27
-
-
27144491599
-
C-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations
-
10.1182/blood-2005-02-0734 1:CAS:528:DC%2BD2MXhtVKqt73I 15972450
-
Luo H, Li Q, O'Neal J, Kreisel F, Le Beau MM et al (2005) c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations. Blood 106:2452-2461
-
(2005)
Blood
, vol.106
, pp. 2452-2461
-
-
Luo, H.1
Li, Q.2
O'Neal, J.3
Kreisel, F.4
Le Beau, M.M.5
-
28
-
-
77953183446
-
Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia
-
10.1172/JCI39964 1:CAS:528:DC%2BC3cXnt1Kqtbs%3D 20484815
-
Xiang Z, Luo H, Payton JE, Cain J, Ley TJ et al (2010) Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia. J Clin Invest 120:2109-2118
-
(2010)
J Clin Invest
, vol.120
, pp. 2109-2118
-
-
Xiang, Z.1
Luo, H.2
Payton, J.E.3
Cain, J.4
Ley, T.J.5
-
29
-
-
62049084053
-
MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family
-
10.1038/onc.2008.466 1:CAS:528:DC%2BD1MXis1Chtb8%3D 19137012
-
Beverly LJ, Varmus HE (2009) MYC-induced myeloid leukemogenesis is accelerated by all six members of the antiapoptotic BCL family. Oncogene 28:1274-1279
-
(2009)
Oncogene
, vol.28
, pp. 1274-1279
-
-
Beverly, L.J.1
Varmus, H.E.2
-
30
-
-
23844469503
-
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
-
10.1038/nature03845 1:CAS:528:DC%2BD2MXnt1Siu7w%3D 16094360
-
Hemann MT, Bric A, Teruya-Feldstein J, Herbst A, Nilsson JA et al (2005) Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature 436:807-811
-
(2005)
Nature
, vol.436
, pp. 807-811
-
-
Hemann, M.T.1
Bric, A.2
Teruya-Feldstein, J.3
Herbst, A.4
Nilsson, J.A.5
-
31
-
-
0037075806
-
A non-transgenic mouse model for B-cell lymphoma: In vivo infection of p53-null bone marrow progenitors by a Myc retrovirus is sufficient for tumorigenesis
-
10.1038/sj.onc.1205244 1:CAS:528:DC%2BD38Xis1ahurs%3D 11896625
-
Yu D, Thomas-Tikhonenko A (2002) A non-transgenic mouse model for B-cell lymphoma: in vivo infection of p53-null bone marrow progenitors by a Myc retrovirus is sufficient for tumorigenesis. Oncogene 21:1922-1927
-
(2002)
Oncogene
, vol.21
, pp. 1922-1927
-
-
Yu, D.1
Thomas-Tikhonenko, A.2
-
32
-
-
0037372543
-
Oscillation between B-lymphoid and myeloid lineages in Myc-induced hematopoietic tumors following spontaneous silencing/reactivation of the EBF/Pax5 pathway
-
10.1182/blood-2002-06-1797 1:CAS:528:DC%2BD3sXhslCrtLs%3D 12406913
-
Yu D, Allman D, Goldschmidt MH, Atchison ML, Monroe JG et al (2003) Oscillation between B-lymphoid and myeloid lineages in Myc-induced hematopoietic tumors following spontaneous silencing/reactivation of the EBF/Pax5 pathway. Blood 101:1950-1955
-
(2003)
Blood
, vol.101
, pp. 1950-1955
-
-
Yu, D.1
Allman, D.2
Goldschmidt, M.H.3
Atchison, M.L.4
Monroe, J.G.5
-
33
-
-
36349014998
-
Overexpression of N-Myc rapidly causes acute myeloid leukemia in mice
-
10.1158/0008-5472.CAN-07-1118 1:CAS:528:DC%2BD2sXhtlSls7vN 18006809
-
Kawagoe H, Kandilci A, Kranenburg TA, Grosveld GC (2007) Overexpression of N-Myc rapidly causes acute myeloid leukemia in mice. Cancer Res 67:10677-10685
-
(2007)
Cancer Res
, vol.67
, pp. 10677-10685
-
-
Kawagoe, H.1
Kandilci, A.2
Kranenburg, T.A.3
Grosveld, G.C.4
-
34
-
-
84857663283
-
Inhibition of the intrinsic but not the extrinsic apoptosis pathway accelerates and drives MYC-driven tumorigenesis towards acute myeloid leukemia
-
10.1371/journal.pone.0031366 22393362
-
Hogstrand K, Hejll E, Sander B, Rozell B, Larsson LG et al (2012) Inhibition of the intrinsic but not the extrinsic apoptosis pathway accelerates and drives MYC-driven tumorigenesis towards acute myeloid leukemia. PLoS ONE 7:e31366
-
(2012)
PLoS ONE
, vol.7
, pp. 31366
-
-
Hogstrand, K.1
Hejll, E.2
Sander, B.3
Rozell, B.4
Larsson, L.G.5
-
35
-
-
0028947580
-
Expression of c-MYC under the control of GATA-1 regulatory sequences causes erythroleukemia in transgenic mice
-
10.1084/jem.181.5.1603 1:CAS:528:DyaK2MXlsVGhtLs%3D 7722440
-
Skoda RC, Tsai SF, Orkin SH, Leder P (1995) Expression of c-MYC under the control of GATA-1 regulatory sequences causes erythroleukemia in transgenic mice. J Exp Med 181:1603-1613
-
(1995)
J Exp Med
, vol.181
, pp. 1603-1613
-
-
Skoda, R.C.1
Tsai, S.F.2
Orkin, S.H.3
Leder, P.4
-
36
-
-
19944369765
-
T-cell lymphomas mask slower developing B-lymphoid and myeloid tumours in transgenic mice with broad haematopoietic expression of MYC
-
10.1038/sj.onc.1208399 1:CAS:528:DC%2BD2MXktlWisL0%3D 15688022
-
Smith DP, Bath ML, Harris AW, Cory S (2005) T-cell lymphomas mask slower developing B-lymphoid and myeloid tumours in transgenic mice with broad haematopoietic expression of MYC. Oncogene 24:3544-3553
-
(2005)
Oncogene
, vol.24
, pp. 3544-3553
-
-
Smith, D.P.1
Bath, M.L.2
Harris, A.W.3
Cory, S.4
-
37
-
-
33646339095
-
MYC levels govern hematopoietic tumor type and latency in transgenic mice
-
10.1182/blood-2006-01-0172 1:CAS:528:DC%2BD28XntFehtbY%3D 16537801
-
Smith DP, Bath ML, Metcalf D, Harris AW, Cory S (2006) MYC levels govern hematopoietic tumor type and latency in transgenic mice. Blood 108:653-661
-
(2006)
Blood
, vol.108
, pp. 653-661
-
-
Smith, D.P.1
Bath, M.L.2
Metcalf, D.3
Harris, A.W.4
Cory, S.5
-
38
-
-
61349104536
-
Introduction and overview of the classification of the myeloid neoplasms
-
S.H. Swerdlow E. Campo N.L. Harris E.S. Jaffe S.A. Pileri (eds) et al. 4 International Agency for Research on Cancer Lyon
-
Vardiman JW, Brunning RD, Arber DA, LeBeau MM, Porwit A et al (2008) Introduction and overview of the classification of the myeloid neoplasms. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA et al (eds) WHO classification of tumours of haematopoietic and lymphoid tissues, 4th edn. International Agency for Research on Cancer, Lyon, pp 18-37
-
(2008)
WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
, pp. 18-37
-
-
Vardiman, J.W.1
Brunning, R.D.2
Arber, D.A.3
Lebeau, M.M.4
Porwit, A.5
-
39
-
-
34249676964
-
Chronic myeloid leukaemia as a model of disease evolution in human cancer
-
10.1038/nrc2147 1:CAS:528:DC%2BD2sXls1KjsL4%3D 17522713
-
Melo JV, Barnes DJ (2007) Chronic myeloid leukaemia as a model of disease evolution in human cancer. Nat Rev Cancer 7:441-453
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 441-453
-
-
Melo, J.V.1
Barnes, D.J.2
-
40
-
-
0037126385
-
Jak2 is involved in c-Myc induction by Bcr-Abl
-
10.1038/sj.onc.1205942 1:CAS:528:DC%2BD38XnsFyksr0%3D 12370803
-
Xie S, Lin H, Sun T, Arlinghaus RB (2002) Jak2 is involved in c-Myc induction by Bcr-Abl. Oncogene 21:7137-7146
-
(2002)
Oncogene
, vol.21
, pp. 7137-7146
-
-
Xie, S.1
Lin, H.2
Sun, T.3
Arlinghaus, R.B.4
-
41
-
-
2942606655
-
C-myc expression in cell lines derived from chronic myeloid leukemia
-
1:CAS:528:DC%2BD2cXotlSrtLw%3D 15003904
-
Gomez-Casares MT, Vaque JP, Lemes A, Molero T, Delgado MD et al (2004) C-myc expression in cell lines derived from chronic myeloid leukemia. Haematologica 89:241-243
-
(2004)
Haematologica
, vol.89
, pp. 241-243
-
-
Gomez-Casares, M.T.1
Vaque, J.P.2
Lemes, A.3
Molero, T.4
Delgado, M.D.5
-
42
-
-
0024603114
-
The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc
-
1:CAS:528:DyaL1MXhs1Ohuro%3D 2725497
-
Lugo TG, Witte ON (1989) The BCR-ABL oncogene transforms Rat-1 cells and cooperates with v-myc. Mol Cell Biol 9:1263-1270
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1263-1270
-
-
Lugo, T.G.1
Witte, O.N.2
-
43
-
-
0026788001
-
Dominant negative MYC blocks transformation by ABL oncogenes
-
10.1016/0092-8674(92)90241-4 1:CAS:528:DyaK38XmtV2qtrg%3D 1525828
-
Sawyers CL, Callahan W, Witte ON (1992) Dominant negative MYC blocks transformation by ABL oncogenes. Cell 70:901-910
-
(1992)
Cell
, vol.70
, pp. 901-910
-
-
Sawyers, C.L.1
Callahan, W.2
Witte, O.N.3
-
44
-
-
0028286140
-
Differential complementation of Bcr-Abl point mutants with c-Myc
-
10.1126/science.8153630 1:CAS:528:DyaK2cXktVKhtbw%3D 8153630
-
Afar DE, Goga A, McLaughlin J, Witte ON, Sawyers CL (1994) Differential complementation of Bcr-Abl point mutants with c-Myc. Science 264:424-426
-
(1994)
Science
, vol.264
, pp. 424-426
-
-
Afar, D.E.1
Goga, A.2
McLaughlin, J.3
Witte, O.N.4
Sawyers, C.L.5
-
45
-
-
72449196261
-
Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics
-
10.1074/mcp.M900285-MCP200 1:CAS:528:DC%2BD1MXhsFOgsL7E 19651622
-
Pan C, Olsen JV, Daub H, Mann M (2009) Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics. Mol Cell Proteomics 8:2796-2808
-
(2009)
Mol Cell Proteomics
, vol.8
, pp. 2796-2808
-
-
Pan, C.1
Olsen, J.V.2
Daub, H.3
Mann, M.4
-
46
-
-
0030986407
-
Bcl-2 and c-myc expression, cell cycle kinetics and apoptosis during the progression of chronic myelogenous leukemia from diagnosis to blastic phase
-
10.1016/S0145-2126(97)00006-4 1:STN:280:DyaK2svisFejuw%3D%3D 9279359
-
Handa H, Hegde UP, Kotelnikov VM, Mundle SD, Dong LM et al (1997) Bcl-2 and c-myc expression, cell cycle kinetics and apoptosis during the progression of chronic myelogenous leukemia from diagnosis to blastic phase. Leuk Res 21:479-489
-
(1997)
Leuk Res
, vol.21
, pp. 479-489
-
-
Handa, H.1
Hegde, U.P.2
Kotelnikov, V.M.3
Mundle, S.D.4
Dong, L.M.5
-
47
-
-
7344233693
-
Changes in oncogene expression implicated in evolution of chronic granulocytic leukemia from its chronic phase to acceleration
-
1:CAS:528:DC%2BD3cXis1aktb0%3D 9713961
-
Beck Z, Bacsi A, Kovacs E, Kiss J, Kiss A et al (1998) Changes in oncogene expression implicated in evolution of chronic granulocytic leukemia from its chronic phase to acceleration. Leuk Lymphoma 30:293-306
-
(1998)
Leuk Lymphoma
, vol.30
, pp. 293-306
-
-
Beck, Z.1
Bacsi, A.2
Kovacs, E.3
Kiss, J.4
Kiss, A.5
-
48
-
-
0038001030
-
Chronic myelogenous leukemia molecular signature
-
10.1038/sj.onc.1206620 1:CAS:528:DC%2BD3sXks1Cntr8%3D 12813469
-
Nowicki MO, Pawlowski P, Fischer T, Hess G, Pawlowski T et al (2003) Chronic myelogenous leukemia molecular signature. Oncogene 22:3952-3963
-
(2003)
Oncogene
, vol.22
, pp. 3952-3963
-
-
Nowicki, M.O.1
Pawlowski, P.2
Fischer, T.3
Hess, G.4
Pawlowski, T.5
-
49
-
-
33847230958
-
Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase
-
10.1038/sj.leu.2404549 1:CAS:528:DC%2BD2sXhvFWktrs%3D 17252012
-
Diaz-Blanco E, Bruns I, Neumann F, Fischer JC, Graef T et al (2007) Molecular signature of CD34(+) hematopoietic stem and progenitor cells of patients with CML in chronic phase. Leukemia 21:494-504
-
(2007)
Leukemia
, vol.21
, pp. 494-504
-
-
Diaz-Blanco, E.1
Bruns, I.2
Neumann, F.3
Fischer, J.C.4
Graef, T.5
-
50
-
-
79956060328
-
MYC in chronic myeloid leukemia: Induction of aberrant DNA synthesis and association with poor response to imatinib
-
10.1158/1541-7786.MCR-10-0356 1:CAS:528:DC%2BC3MXmtVGlsbo%3D 21460180
-
Albajar M, Gomez-Casares MT, Llorca J, Mauleon I, Vaque JP et al (2011) MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib. Mol Cancer Res 9:564-576
-
(2011)
Mol Cancer Res
, vol.9
, pp. 564-576
-
-
Albajar, M.1
Gomez-Casares, M.T.2
Llorca, J.3
Mauleon, I.4
Vaque, J.P.5
-
51
-
-
79959252521
-
Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression
-
10.1182/blood-2010-08-304477 1:CAS:528:DC%2BC3MXot1Gqt7o%3D 21490338
-
Lucas CM, Harris RJ, Giannoudis A, Copland M, Slupsky JR et al (2011) Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression. Blood 117:6660-6668
-
(2011)
Blood
, vol.117
, pp. 6660-6668
-
-
Lucas, C.M.1
Harris, R.J.2
Giannoudis, A.3
Copland, M.4
Slupsky, J.R.5
-
52
-
-
0036202470
-
Cytogenetic and molecular genetic evolution of chronic myeloid leukemia
-
10.1159/000046636 1:CAS:528:DC%2BD38XitlGmsLs%3D 11919388
-
Johansson B, Fioretos T, Mitelman F (2002) Cytogenetic and molecular genetic evolution of chronic myeloid leukemia. Acta Haematol 107:76-94
-
(2002)
Acta Haematol
, vol.107
, pp. 76-94
-
-
Johansson, B.1
Fioretos, T.2
Mitelman, F.3
-
53
-
-
34848897224
-
Genomic profile of chronic myelogenous leukemia: Imbalances associated with disease progression
-
10.1002/gcc.20487 1:CAS:528:DC%2BD2sXhtFGmt7vE 17696194
-
Brazma D, Grace C, Howard J, Melo JV, Holyoke T et al (2007) Genomic profile of chronic myelogenous leukemia: imbalances associated with disease progression. Genes Chromosomes Cancer 46:1039-1050
-
(2007)
Genes Chromosomes Cancer
, vol.46
, pp. 1039-1050
-
-
Brazma, D.1
Grace, C.2
Howard, J.3
Melo, J.V.4
Holyoke, T.5
-
54
-
-
13944252067
-
The life cycle of C-myc: From synthesis to degradation
-
10.4161/cc.3.9.1145 1:CAS:528:DC%2BD2MXntVanuro%3D 15467447
-
Sears RC (2004) The life cycle of C-myc: from synthesis to degradation. Cell Cycle 3:1133-1137
-
(2004)
Cell Cycle
, vol.3
, pp. 1133-1137
-
-
Sears, R.C.1
-
55
-
-
80051985500
-
C-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in chronic myelogenous leukemia CD34 + hematopoietic progenitor cells
-
10.1158/1541-7786.MCR-10-0510 1:CAS:528:DC%2BC3MXhtVajtb3N 21693596
-
Porro A, Iraci N, Soverini S, Diolaiti D, Gherardi S et al (2011) c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in chronic myelogenous leukemia CD34 + hematopoietic progenitor cells. Mol Cancer Res 9:1054-1066
-
(2011)
Mol Cancer Res
, vol.9
, pp. 1054-1066
-
-
Porro, A.1
Iraci, N.2
Soverini, S.3
Diolaiti, D.4
Gherardi, S.5
-
56
-
-
61849163272
-
Molecular biology of bcr-abl1-positive chronic myeloid leukemia
-
10.1182/blood-2008-03-144790 1:CAS:528:DC%2BD1MXisV2iurs%3D 18827185
-
Quintas-Cardama A, Cortes J (2009) Molecular biology of bcr-abl1-positive chronic myeloid leukemia. Blood 113:1619-1630
-
(2009)
Blood
, vol.113
, pp. 1619-1630
-
-
Quintas-Cardama, A.1
Cortes, J.2
-
57
-
-
84876898096
-
MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27KIP1
-
doi: 10.1038/onc.2012.246
-
Gomez-Casares MT, Garcia-Alegria E, Lopez-Jorge CE, Ferrandiz N, Blanco R, et al. (2012) MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27KIP1. Oncogene. doi: 10.1038/onc.2012.246
-
(2012)
Oncogene
-
-
Gomez-Casares, M.T.1
Garcia-Alegria, E.2
Lopez-Jorge, C.E.3
Ferrandiz, N.4
Blanco, R.5
-
58
-
-
41249102333
-
The expression levels of telomerase catalytic subunit hTERT and oncogenic MYC in essential thrombocythemia are affected by the molecular subtype
-
10.1007/s00277-007-0424-1 1:CAS:528:DC%2BD1cXjsVGjtLs%3D 18084761
-
Theophile K, Buesche G, Kreipe H, Bock O (2008) The expression levels of telomerase catalytic subunit hTERT and oncogenic MYC in essential thrombocythemia are affected by the molecular subtype. Ann Hematol 87:263-268
-
(2008)
Ann Hematol
, vol.87
, pp. 263-268
-
-
Theophile, K.1
Buesche, G.2
Kreipe, H.3
Bock, O.4
-
59
-
-
15844389026
-
JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells
-
10.1074/jbc.271.21.12681 1:CAS:528:DyaK28XjtFantb8%3D 8647882
-
Watanabe S, Itoh T, Arai K (1996) JAK2 is essential for activation of c-fos and c-myc promoters and cell proliferation through the human granulocyte-macrophage colony-stimulating factor receptor in BA/F3 cells. J Biol Chem 271:12681-12686
-
(1996)
J Biol Chem
, vol.271
, pp. 12681-12686
-
-
Watanabe, S.1
Itoh, T.2
Arai, K.3
-
60
-
-
0022456097
-
Expression of growth-regulated genes in human acute leukemias
-
1:CAS:528:DyaL28XlvVGit78%3D 3756869
-
Ferrari S, Narni F, Mars W, Kaczmarek L, Venturelli D et al (1986) Expression of growth-regulated genes in human acute leukemias. Cancer Res 46:5162-5166
-
(1986)
Cancer Res
, vol.46
, pp. 5162-5166
-
-
Ferrari, S.1
Narni, F.2
Mars, W.3
Kaczmarek, L.4
Venturelli, D.5
-
61
-
-
0022494582
-
Altered expression of G1-specific genes in human malignant myeloid cells
-
10.1073/pnas.83.5.1495 1:CAS:528:DyaL28XhsVKnsro%3D 3513178
-
Calabretta B, Venturelli D, Kaczmarek L, Narni F, Talpaz M et al (1986) Altered expression of G1-specific genes in human malignant myeloid cells. Proc Natl Acad Sci USA 83:1495-1498
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 1495-1498
-
-
Calabretta, B.1
Venturelli, D.2
Kaczmarek, L.3
Narni, F.4
Talpaz, M.5
-
62
-
-
52449135516
-
Upregulation of c-myc gene accompanied by PU.1 deficiency in radiation-induced acute myeloid leukemia in mice
-
10.1016/j.exphem.2008.01.015 1:CAS:528:DC%2BD1cXnsF2ktrs%3D 18375040
-
Hirouchi T, Takabatake T, Yoshida K, Nitta Y, Nakamura M et al (2008) Upregulation of c-myc gene accompanied by PU.1 deficiency in radiation-induced acute myeloid leukemia in mice. Exp Hematol 36:871-885
-
(2008)
Exp Hematol
, vol.36
, pp. 871-885
-
-
Hirouchi, T.1
Takabatake, T.2
Yoshida, K.3
Nitta, Y.4
Nakamura, M.5
-
63
-
-
2442517390
-
DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines
-
10.1016/j.leukres.2003.11.011 1:CAS:528:DC%2BD2cXkt1Smsbk%3D 15158096
-
Court EL, Smith MA, Avent ND, Hancock JT, Morgan LM et al (2004) DNA microarray screening of differential gene expression in bone marrow samples from AML, non-AML patients and AML cell lines. Leuk Res 28:743-753
-
(2004)
Leuk Res
, vol.28
, pp. 743-753
-
-
Court, E.L.1
Smith, M.A.2
Avent, N.D.3
Hancock, J.T.4
Morgan, L.M.5
-
64
-
-
11144358111
-
Prognostically useful gene-expression profiles in acute myeloid leukemia
-
10.1056/NEJMoa040465 1:CAS:528:DC%2BD2cXjt1Wlu7g%3D 15084694
-
Valk PJ, Verhaak RG, Beijen MA, Erpelinck CA, Barjesteh van Waalwijk van Doorn-Khosrovani S et al (2004) Prognostically useful gene-expression profiles in acute myeloid leukemia. N Engl J Med 350:1617-1628
-
(2004)
N Engl J Med
, vol.350
, pp. 1617-1628
-
-
Valk, P.J.1
Verhaak, R.G.2
Beijen, M.A.3
Erpelinck, C.A.4
Barjesteh Van Waalwijk Van Doorn-Khosrovani, S.5
-
65
-
-
9444283773
-
Gene expression profiling of pediatric acute myelogenous leukemia
-
10.1182/blood-2004-03-1154 1:CAS:528:DC%2BD2cXhtVGltbzI 15226186
-
Ross ME, Mahfouz R, Onciu M, Liu HC, Zhou X et al (2004) Gene expression profiling of pediatric acute myelogenous leukemia. Blood 104:3679-3687
-
(2004)
Blood
, vol.104
, pp. 3679-3687
-
-
Ross, M.E.1
Mahfouz, R.2
Onciu, M.3
Liu, H.C.4
Zhou, X.5
-
66
-
-
36549022557
-
Identification of genes with abnormal expression changes in acute myeloid leukemia
-
10.1002/gcc.20500 1:CAS:528:DC%2BD2sXhsVWrtrjF 17910043
-
Stirewalt DL, Meshinchi S, Kopecky KJ, Fan W, Pogosova-Agadjanyan EL et al (2008) Identification of genes with abnormal expression changes in acute myeloid leukemia. Genes Chromosomes Cancer 47:8-20
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 8-20
-
-
Stirewalt, D.L.1
Meshinchi, S.2
Kopecky, K.J.3
Fan, W.4
Pogosova-Agadjanyan, E.L.5
-
67
-
-
0035118130
-
A modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to Ras and Raf transformation
-
1:CAS:528:DC%2BD3MXhsFSqs7c%3D 11221849
-
Bazarov AV, Adachi S, Li SF, Mateyak MK, Wei S et al (2001) A modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to Ras and Raf transformation. Cancer Res 61:1178-1186
-
(2001)
Cancer Res
, vol.61
, pp. 1178-1186
-
-
Bazarov, A.V.1
Adachi, S.2
Li, S.F.3
Mateyak, M.K.4
Wei, S.5
-
68
-
-
0036792667
-
C-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression
-
10.1101/gad.1024602 1:CAS:528:DC%2BD38XnvVGjt7g%3D 12368264
-
Baudino TA, McKay C, Pendeville-Samain H, Nilsson JA, Maclean KH et al (2002) c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression. Genes Dev 16:2530-2543
-
(2002)
Genes Dev
, vol.16
, pp. 2530-2543
-
-
Baudino, T.A.1
McKay, C.2
Pendeville-Samain, H.3
Nilsson, J.A.4
Maclean, K.H.5
-
69
-
-
56849093474
-
Distinct thresholds govern Myc's biological output in vivo
-
10.1016/j.ccr.2008.10.018 1:CAS:528:DC%2BD1cXhsFahsrfK 19061836
-
Murphy DJ, Junttila MR, Pouyet L, Karnezis A, Shchors K et al (2008) Distinct thresholds govern Myc's biological output in vivo. Cancer Cell 14:447-457
-
(2008)
Cancer Cell
, vol.14
, pp. 447-457
-
-
Murphy, D.J.1
Junttila, M.R.2
Pouyet, L.3
Karnezis, A.4
Shchors, K.5
-
70
-
-
12144287598
-
Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells
-
10.1128/MCB.24.7.2890-2904.2004 15024077
-
Muller-Tidow C, Steffen B, Cauvet T, Tickenbrock L, Ji P et al (2004) Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells. Mol Cell Biol 24:2890-2904
-
(2004)
Mol Cell Biol
, vol.24
, pp. 2890-2904
-
-
Muller-Tidow, C.1
Steffen, B.2
Cauvet, T.3
Tickenbrock, L.4
Ji, P.5
-
71
-
-
76249093980
-
Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC
-
10.1182/blood-2009-03-206524 1:CAS:528:DC%2BC3cXhtFejtQ%3D%3D 19855079
-
Rice KL, Hormaeche I, Doulatov S, Flatow JM, Grimwade D et al (2009) Comprehensive genomic screens identify a role for PLZF-RARalpha as a positive regulator of cell proliferation via direct regulation of c-MYC. Blood 114:5499-5511
-
(2009)
Blood
, vol.114
, pp. 5499-5511
-
-
Rice, K.L.1
Hormaeche, I.2
Doulatov, S.3
Flatow, J.M.4
Grimwade, D.5
-
72
-
-
0035419401
-
MLL-ENL causes a reversible and myc-dependent block of myelomonocytic cell differentiation
-
1:CAS:528:DC%2BD3MXmsF2jsbg%3D 11522644
-
Schreiner S, Birke M, Garcia-Cuellar MP, Zilles O, Greil J et al (2001) MLL-ENL causes a reversible and myc-dependent block of myelomonocytic cell differentiation. Cancer Res 61:6480-6486
-
(2001)
Cancer Res
, vol.61
, pp. 6480-6486
-
-
Schreiner, S.1
Birke, M.2
Garcia-Cuellar, M.P.3
Zilles, O.4
Greil, J.5
-
73
-
-
0036211828
-
Double minute chromosomes in acute myeloid leukemia and myelodysplastic syndrome: Identification of new amplification regions by fluorescence in situ hybridization and spectral karyotyping
-
10.1002/gcc.10038 1:CAS:528:DC%2BD38XjtFWju70%3D 11921281
-
Sait SN, Qadir MU, Conroy JM, Matsui S, Nowak NJ et al (2002) Double minute chromosomes in acute myeloid leukemia and myelodysplastic syndrome: identification of new amplification regions by fluorescence in situ hybridization and spectral karyotyping. Genes Chromosomes Cancer 34:42-47
-
(2002)
Genes Chromosomes Cancer
, vol.34
, pp. 42-47
-
-
Sait, S.N.1
Qadir, M.U.2
Conroy, J.M.3
Matsui, S.4
Nowak, N.J.5
-
74
-
-
0028078646
-
Localization of amplified MYC gene sequences to double minute chromosomes in acute myelogenous leukemia
-
10.1002/gcc.2870090111 1:CAS:528:DyaK2cXis1Ojsrk%3D 7507702
-
Slovak ML, Ho JP, Pettenati MJ, Khan A, Douer D et al (1994) Localization of amplified MYC gene sequences to double minute chromosomes in acute myelogenous leukemia. Genes Chromosomes Cancer 9:62-67
-
(1994)
Genes Chromosomes Cancer
, vol.9
, pp. 62-67
-
-
Slovak, M.L.1
Ho, J.P.2
Pettenati, M.J.3
Khan, A.4
Douer, D.5
-
75
-
-
67651083576
-
Gene amplification in myeloid leukemias elucidated by fluorescence in situ hybridization
-
10.1016/j.cancergencyto.2009.04.006 1:CAS:528:DC%2BD1MXosVGltbk%3D 19602463
-
Rayeroux KC, Campbell LJ (2009) Gene amplification in myeloid leukemias elucidated by fluorescence in situ hybridization. Cancer Genet Cytogenet 193:44-53
-
(2009)
Cancer Genet Cytogenet
, vol.193
, pp. 44-53
-
-
Rayeroux, K.C.1
Campbell, L.J.2
-
76
-
-
0032988568
-
MYC amplification in two further cases of acute myeloid leukemia with trisomy 4 and double minute chromosomes
-
10.1016/S0165-4608(98)00160-5 10087944
-
O'Malley F, Rayeroux K, Cole-Sinclair M, Tong M, Campbell LJ (1999) MYC amplification in two further cases of acute myeloid leukemia with trisomy 4 and double minute chromosomes. Cancer Genet Cytogenet 109:123-125
-
(1999)
Cancer Genet Cytogenet
, vol.109
, pp. 123-125
-
-
O'Malley, F.1
Rayeroux, K.2
Cole-Sinclair, M.3
Tong, M.4
Campbell, L.J.5
-
77
-
-
4243118608
-
Double minute chromosomes in monoblastic (M5) and myeloblastic (M2) acute myeloid leukemia: Two case reports and a review of literature
-
10.1002/ajh.20151 15307107
-
Thomas L, Stamberg J, Gojo I, Ning Y, Rapoport AP (2004) Double minute chromosomes in monoblastic (M5) and myeloblastic (M2) acute myeloid leukemia: two case reports and a review of literature. Am J Hematol 77:55-61
-
(2004)
Am J Hematol
, vol.77
, pp. 55-61
-
-
Thomas, L.1
Stamberg, J.2
Gojo, I.3
Ning, Y.4
Rapoport, A.P.5
-
78
-
-
0033934638
-
Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia
-
10.1038/sj.leu.2401782 1:STN:280:DC%2BD3czovVajtg%3D%3D 10914558
-
Mathew S, Lorsbach RB, Shearer P, Sandlund JT, Raimondi SC (2000) Double minute chromosomes and c-MYC amplification in a child with secondary myelodysplastic syndrome after treatment for acute lymphoblastic leukemia. Leukemia 14:1314-1315
-
(2000)
Leukemia
, vol.14
, pp. 1314-1315
-
-
Mathew, S.1
Lorsbach, R.B.2
Shearer, P.3
Sandlund, J.T.4
Raimondi, S.C.5
-
79
-
-
33644773649
-
MYC-containing double minutes in hematologic malignancies: Evidence in favor of the episome model and exclusion of MYC as the target gene
-
10.1093/hmg/ddl010 1:CAS:528:DC%2BD28XitVGmtr8%3D 16452126
-
Storlazzi CT, Fioretos T, Surace C, Lonoce A, Mastrorilli A et al (2006) MYC-containing double minutes in hematologic malignancies: evidence in favor of the episome model and exclusion of MYC as the target gene. Hum Mol Genet 15:933-942
-
(2006)
Hum Mol Genet
, vol.15
, pp. 933-942
-
-
Storlazzi, C.T.1
Fioretos, T.2
Surace, C.3
Lonoce, A.4
Mastrorilli, A.5
-
80
-
-
74949095432
-
Concomitant and successive amplifications of MYC in APL-like leukemia
-
10.1016/j.cancergencyto.2009.11.001 1:CAS:528:DC%2BC3cXhtlGhs7c%3D 20113841
-
Bruyere H, Sutherland H, Chipperfield K, Hudoba M (2010) Concomitant and successive amplifications of MYC in APL-like leukemia. Cancer Genet Cytogenet 197:75-80
-
(2010)
Cancer Genet Cytogenet
, vol.197
, pp. 75-80
-
-
Bruyere, H.1
Sutherland, H.2
Chipperfield, K.3
Hudoba, M.4
-
81
-
-
78651539523
-
Evidence-based genomic diagnosis characterized chromosomal and cryptic imbalances in 30 elderly patients with myelodysplastic syndrome and acute myeloid leukemia
-
10.1186/1755-8166-4-3 21251322
-
Bajaj R, Xu F, Xiang B, Wilcox K, Diadamo AJ et al (2011) Evidence-based genomic diagnosis characterized chromosomal and cryptic imbalances in 30 elderly patients with myelodysplastic syndrome and acute myeloid leukemia. Mol Cytogenet 4:3
-
(2011)
Mol Cytogenet
, vol.4
, pp. 3
-
-
Bajaj, R.1
Xu, F.2
Xiang, B.3
Wilcox, K.4
Diadamo, A.J.5
-
82
-
-
82955236130
-
Amplification of the G allele at SNP rs6983267 in 8q24 amplicons in myeloid malignancies as cause of the lack of MYC overexpression?
-
10.1016/j.bcmd.2011.09.001 1:CAS:528:DC%2BC3MXhsV2gsr3J 21945030
-
Micale L, Augello B, Daniele G, Macchia G, L'Abbate A et al (2011) Amplification of the G allele at SNP rs6983267 in 8q24 amplicons in myeloid malignancies as cause of the lack of MYC overexpression? Blood Cells Mol Dis 47:259-261
-
(2011)
Blood Cells Mol Dis
, vol.47
, pp. 259-261
-
-
Micale, L.1
Augello, B.2
Daniele, G.3
Macchia, G.4
L'Abbate, A.5
-
83
-
-
0037397775
-
MYC is not overexpressed in a case of chronic myelomonocytic leukemia with MYC-containing double minutes
-
10.1038/sj.leu.2402841 1:STN:280:DC%2BD3s7msVyqug%3D%3D 12682646
-
Paulsson K, Lassen C, Kuric N, Billstrom R, Fioretos T et al (2003) MYC is not overexpressed in a case of chronic myelomonocytic leukemia with MYC-containing double minutes. Leukemia 17:813-815
-
(2003)
Leukemia
, vol.17
, pp. 813-815
-
-
Paulsson, K.1
Lassen, C.2
Kuric, N.3
Billstrom, R.4
Fioretos, T.5
-
84
-
-
33947224233
-
CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins
-
10.1182/blood-2006-01-030643 1:CAS:528:DC%2BD2sXnslygs7g%3D 17090657
-
Sloand EM, Pfannes L, Chen G, Shah S, Solomou EE et al (2007) CD34 cells from patients with trisomy 8 myelodysplastic syndrome (MDS) express early apoptotic markers but avoid programmed cell death by up-regulation of antiapoptotic proteins. Blood 109:2399-2405
-
(2007)
Blood
, vol.109
, pp. 2399-2405
-
-
Sloand, E.M.1
Pfannes, L.2
Chen, G.3
Shah, S.4
Solomou, E.E.5
-
85
-
-
77950640767
-
Increased MYC gene copy number correlates with increased mRNA levels in diffuse large B-cell lymphoma
-
10.3324/haematol.2009.012864 1:CAS:528:DC%2BC3cXhtlWjsL7I 20378577
-
Stasik CJ, Nitta H, Zhang W, Mosher CH, Cook JR et al (2010) Increased MYC gene copy number correlates with increased mRNA levels in diffuse large B-cell lymphoma. Haematologica 95:597-603
-
(2010)
Haematologica
, vol.95
, pp. 597-603
-
-
Stasik, C.J.1
Nitta, H.2
Zhang, W.3
Mosher, C.H.4
Cook, J.R.5
-
86
-
-
77957162079
-
A distinct expression of various gene subsets in CD34 + cells from patients with early and advanced myelodysplastic syndrome
-
10.1016/j.leukres.2010.02.021 1:CAS:528:DC%2BC3cXhtl2isL7N 20303173
-
Vasikova A, Belickova M, Budinska E, Cermak J (2010) A distinct expression of various gene subsets in CD34 + cells from patients with early and advanced myelodysplastic syndrome. Leuk Res 34:1566-1572
-
(2010)
Leuk Res
, vol.34
, pp. 1566-1572
-
-
Vasikova, A.1
Belickova, M.2
Budinska, E.3
Cermak, J.4
-
87
-
-
4544221109
-
Omomyc expression in skin prevents Myc-induced papillomatosis
-
10.1038/sj.cdd.4401443 1:CAS:528:DC%2BD2cXmslWhsbs%3D 15143346
-
Soucek L, Nasi S, Evan GI (2004) Omomyc expression in skin prevents Myc-induced papillomatosis. Cell Death Differ 11:1038-1045
-
(2004)
Cell Death Differ
, vol.11
, pp. 1038-1045
-
-
Soucek, L.1
Nasi, S.2
Evan, G.I.3
-
88
-
-
53349103292
-
Modelling Myc inhibition as a cancer therapy
-
10.1038/nature07260 1:CAS:528:DC%2BD1cXhtF2hsbnO 18716624
-
Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ et al (2008) Modelling Myc inhibition as a cancer therapy. Nature 455:679-683
-
(2008)
Nature
, vol.455
, pp. 679-683
-
-
Soucek, L.1
Whitfield, J.2
Martins, C.P.3
Finch, A.J.4
Murphy, D.J.5
-
89
-
-
78650246896
-
Inhibition of Myc effectively targets KRAS mutation-positive lung cancer expressing high levels of Myc
-
1:CAS:528:DC%2BC3MXktFym 21036740
-
Fukazawa T, Maeda Y, Matsuoka J, Yamatsuji T, Shigemitsu K et al (2010) Inhibition of Myc effectively targets KRAS mutation-positive lung cancer expressing high levels of Myc. Anticancer Res 30:4193-4200
-
(2010)
Anticancer Res
, vol.30
, pp. 4193-4200
-
-
Fukazawa, T.1
Maeda, Y.2
Matsuoka, J.3
Yamatsuji, T.4
Shigemitsu, K.5
-
90
-
-
79955403911
-
Endogenous Myc maintains the tumor microenvironment
-
10.1101/gad.2038411 1:CAS:528:DC%2BC3MXlvFyqtb0%3D 21478273
-
Sodir NM, Swigart LB, Karnezis AN, Hanahan D, Evan GI et al (2011) Endogenous Myc maintains the tumor microenvironment. Genes Dev 25:907-916
-
(2011)
Genes Dev
, vol.25
, pp. 907-916
-
-
Sodir, N.M.1
Swigart, L.B.2
Karnezis, A.N.3
Hanahan, D.4
Evan, G.I.5
-
91
-
-
56749184298
-
Reflecting on 25 years with MYC
-
10.1038/nrc2231 1:CAS:528:DC%2BD1cXhsVWhu7rJ 19029958
-
Meyer N, Penn LZ (2008) Reflecting on 25 years with MYC. Nat Rev Cancer 8:976-990
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 976-990
-
-
Meyer, N.1
Penn, L.Z.2
-
92
-
-
52449101436
-
Transcription-independent functions of MYC: Regulation of translation and DNA replication
-
10.1038/nrm2467 1:CAS:528:DC%2BD1cXhtFGhsLrJ 18698328
-
Cole MD, Cowling VH (2008) Transcription-independent functions of MYC: regulation of translation and DNA replication. Nat Rev Mol Cell Biol 9:810-815
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 810-815
-
-
Cole, M.D.1
Cowling, V.H.2
-
93
-
-
84858865110
-
MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiency
-
10.1158/1541-7786.MCR-11-0508 1:CAS:528:DC%2BC38Xltl2mtLo%3D 22301954
-
Moser R, Toyoshima M, Robinson K, Gurley KE, Howie HL et al (2012) MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiency. Mol Cancer Res 10:535-545
-
(2012)
Mol Cancer Res
, vol.10
, pp. 535-545
-
-
Moser, R.1
Toyoshima, M.2
Robinson, K.3
Gurley, K.E.4
Howie, H.L.5
-
94
-
-
77956369534
-
Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase
-
10.1073/pnas.1008366107 1:CAS:528:DC%2BC3cXhtVWmtrfF 20643922
-
Yang D, Liu H, Goga A, Kim S, Yuneva M et al (2010) Therapeutic potential of a synthetic lethal interaction between the MYC proto-oncogene and inhibition of aurora-B kinase. Proc Natl Acad Sci USA 107:13836-13841
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 13836-13841
-
-
Yang, D.1
Liu, H.2
Goga, A.3
Kim, S.4
Yuneva, M.5
-
95
-
-
82955203422
-
Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors
-
10.1038/nsmb.2189 1:CAS:528:DC%2BC3MXhsFeit7vN 22120667
-
Murga M, Campaner S, Lopez-Contreras AJ, Toledo LI, Soria R, Montaña MF, D'Artista L, Schleker T, Guerra C, Garcia E, Barbacid M, Hidalgo M, Amati B, Fernandez-Capetillo O (2011) Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors. Nat Struct Mol Biol 18:1331-1335
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 1331-1335
-
-
Murga, M.1
Campaner, S.2
Lopez-Contreras, A.J.3
Toledo, L.I.4
Soria, R.5
Montaña, M.F.6
D'Artista, L.7
Schleker, T.8
Guerra, C.9
Garcia, E.10
Barbacid, M.11
Hidalgo, M.12
Amati, B.13
Fernandez-Capetillo, O.14
-
96
-
-
84862183087
-
Functional genomics identifies therapeutic targets for MYC-driven cancer
-
10.1073/pnas.1121119109 1:CAS:528:DC%2BC38Xptlahs7Y%3D 22623531
-
Toyoshima M, Howie HL, Imakura M, Walsh RM, Annis JE et al (2012) Functional genomics identifies therapeutic targets for MYC-driven cancer. Proc Natl Acad Sci USA 109:9545-9550
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 9545-9550
-
-
Toyoshima, M.1
Howie, H.L.2
Imakura, M.3
Walsh, R.M.4
Annis, J.E.5
-
97
-
-
80052955256
-
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
-
10.1016/j.cell.2011.08.017 1:CAS:528:DC%2BC3MXhtF2ht7fF 21889194
-
Delmore JE, Issa GC, Lemieux ME, Rahl PB, Shi J et al (2011) BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 146:904-917
-
(2011)
Cell
, vol.146
, pp. 904-917
-
-
Delmore, J.E.1
Issa, G.C.2
Lemieux, M.E.3
Rahl, P.B.4
Shi, J.5
-
98
-
-
0036279152
-
Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis
-
1:CAS:528:DC%2BD38XlsFCit7o%3D 12031912
-
Larramendy ML, Niini T, Elonen E, Nagy B, Ollila J et al (2002) Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis. Haematologica 87:569-577
-
(2002)
Haematologica
, vol.87
, pp. 569-577
-
-
Larramendy, M.L.1
Niini, T.2
Elonen, E.3
Nagy, B.4
Ollila, J.5
-
99
-
-
0037069425
-
Expression profiling of CD34 + hematopoietic stem/progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia
-
10.1073/pnas.222491799 1:CAS:528:DC%2BD38Xpt1yrtLg%3D 12417757
-
Qian Z, Fernald AA, Godley LA, Larson RA, Le Beau MM (2002) Expression profiling of CD34+ hematopoietic stem/progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia. Proc Natl Acad Sci USA 99:14925-14930
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 14925-14930
-
-
Qian, Z.1
Fernald, A.A.2
Godley, L.A.3
Larson, R.A.4
Le Beau, M.M.5
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