Second-Generation Tunable pH-Sensitive Phosphoramidate-Based Linkers for Controlled Release

Bioconjugate Chemistry

Volumn 27, Issue 9, 2016, Pages 2206-2213

  Choy, Cindy J ^a   Ley, Corinne R ^a   Davis, Austen L ^a   Backer, Brian S ^a   Geruntho, Jonathan J ^a   Clowers, Brian H ^a   Berkman, Clifford E ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONTROLLED DRUG DELIVERY; DRUG PRODUCTS; ESTERS; HYDROLYSIS; PH SENSORS; PHYSIOLOGICAL MODELS; SCAFFOLDS; STENTS; TARGETED DRUG DELIVERY;

ACIDIC CONDITIONS; CONTROLLED RELEASE; DRUG RELEASE; DRUG-CONJUGATES; ENZYMATIC ACTION; PH SENSITIVE; PHOSPHORAMIDATES; PROPERTY; SECOND GENERATION; TUNABLES;

CARBOXYLIC ACIDS;

AMINE; CARBOXYLIC ACID; MOLECULAR SCAFFOLD; NITROGEN; PHOSPHORAMIDIC ACID DERIVATIVE; PHOSPHORUS; AMIDE; DELAYED RELEASE FORMULATION; DRUG CARRIER; PHOSPHORAMIDIC ACID; PHOSPHORIC ACID;

ACIDITY; ARTICLE; CELL TRACKING; CHEMICAL BOND; CONTROLLED DRUG RELEASE; DRUG STABILITY; DRUG SYNTHESIS; ENDOSOME; ESTERIFICATION; HYDROLYSIS; PH; CHEMISTRY; DELAYED RELEASE FORMULATION; TEMPERATURE;

AMIDES; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; PHOSPHORIC ACIDS; TEMPERATURE;

EID: 84988643541     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.6b00422     Document Type: Article

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