Diagnostic Accuracy of a Host Gene Expression Signature That Discriminates Clinical Severe Sepsis Syndrome and Infection-Negative Systemic Inflammation among Critically Ill Children

Critical Care Medicine

Volumn 45, Issue 4, 2017, Pages e418-e425

  Zimmerman, Jerry J ^a,b   Sullivan, Erin ^a   Yager, Thomas D ^c   Cheng, Catherine ^a   Permut, Lester ^a,b   Cermelli, Silvia ^c   McHugh, Leo ^c   Sampson, Dayle ^c   Seldon, Therese ^c   Brandon, Richard B ^c   Brandon, Roslyn A ^c  

^a SEATTLE CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c Immunexpress   (United States)

Author keywords

classifier; mRNA; pediatric; sepsis; systemic inflammation

Indexed keywords

MESSENGER RNA;

ARTICLE; CARDIOPULMONARY BYPASS; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY CARE UNIT; CRITICALLY ILL PATIENT; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HUMAN; MALE; MOLECULAR DIAGNOSTICS; MRNA EXPRESSION ASSAY; NEXT GENERATION SEQUENCING; OBSERVATIONAL STUDY; PEDIATRIC INTENSIVE CARE UNIT; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION; RNA SEQUENCE; SCHOOL CHILD; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; WASHINGTON; ADOLESCENT; AREA UNDER THE CURVE; CRITICAL ILLNESS; DIFFERENTIAL DIAGNOSIS; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENETICS; GENOTYPE; INFANT; INFLAMMATION; MICROBIOLOGY; POSTOPERATIVE PERIOD; PRESCHOOL CHILD; PROCEDURES; SEVERITY OF ILLNESS INDEX;

ADOLESCENT; AREA UNDER CURVE; CARDIOPULMONARY BYPASS; CHILD; CHILD, PRESCHOOL; CRITICAL ILLNESS; DIAGNOSIS, DIFFERENTIAL; FEMALE; GENE EXPRESSION PROFILING; GENOTYPE; HUMANS; INFANT; INFLAMMATION; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POSTOPERATIVE PERIOD; PROSPECTIVE STUDIES; RNA, MESSENGER; ROC CURVE; SEVERITY OF ILLNESS INDEX; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 84988596362     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000002100     Document Type: Article

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