A new method for the characterization of strain-specific conformational stability of protease-sensitive and protease-resistant PrPSc

PLoS ONE

Volumn 5, Issue 9, 2010, Pages 1-13

  Pirisinu, Laura ^a   di Bari, Michele ^a   Marcon, Stefano ^a   Vaccari, Gabriele ^a   D'Agostino, Claudia ^a   Fazzi, Paola ^a   Esposito, Elena ^a   Galeno, Roberta ^a   Langeveld, Jan ^b   Agrimi, Umberto ^a   Nonno, Romolo ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE HYDROLASE; PRION PROTEIN; PROTEINASE; PROTEINASE K;

ANIMAL; ANIMAL DISEASE; ANIMAL TISSUE; ARTICLE; ARVICOLINAE; BIOCHEMISTRY; BRAIN HOMOGENATE; CENTRIFUGATION; CHEMICAL ANALYSIS; CHEMISTRY; CONTROLLED STUDY; ENZYME ASSAY; ENZYME CONFORMATION; EVALUATION; HUMAN; HUMAN TISSUE; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; MOLECULAR STABILITY; NONHUMAN; PRION; PRION DISEASE; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN STABILITY; SHEEP; SOLUBILITY; SPECIES DIFFERENCE; VIRUS ISOLATION; VIRUS RESISTANCE; VIRUS TRANSMISSION; VOLE;

ANIMALS; ARVICOLINAE; CHEMISTRY; CHEMISTRY TECHNIQUES, ANALYTICAL; HUMANS; ISOLATION AND PURIFICATION; METABOLISM; METHODS; PEPTIDE HYDROLASES; PRION DISEASES; PROTEIN CONFORMATION; PROTEIN STABILITY; PRPC PROTEINS; PRPSC PROTEINS; SHEEP; SOLUBILITY; SPECIES SPECIFICITY; VETERINARY;

MURIDAE; OVIS ARIES;

EID: 84988431510     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012723     Document Type: Article

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