Deciphering how LIP2 and POX2 promoters can optimally regulate recombinant protein production in the yeast Yarrowia lipolytica

Microbial Cell Factories

Volumn 15, Issue 1, 2016, Pages

  Sassi, Hosni ^a   Delvigne, Frank ^b   Kar, Tambi ^b   Nicaud, Jean Marc ^c   Coq, Anne Marie Crutz Le ^c   Steels, Sebastien ^b   Fickers, Patrick ^a,b  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITÉ PARIS SACLAY   (France)

Author keywords

Carbon source; Co substrate; LIP2; POX2; Promoter regulation; Recombinant protein; Yarriwia lipolytica

Indexed keywords

GLUCOSE; GLYCEROL; OLEIC ACID; RECOMBINANT PROTEIN; RED FLUORESCENT PROTEIN; CARBON; CULTURE MEDIUM; FUNGAL PROTEIN; LIP2 PROTEIN, YARROWIA LIPOLYTICA; METHYL OLEATE; TRIACYLGLYCEROL LIPASE;

ARTICLE; BIOACCUMULATION; BIOMASS PRODUCTION; CARBON SOURCE; CELL GROWTH; CELL METABOLISM; CONTROLLED STUDY; CULTURE MEDIUM; FLUORESCENCE ANALYSIS; FUNGAL CELL; FUNGAL GENE; FUNGUS CULTURE; GENE EXPRESSION; GENETIC REGULATION; LIP2 GENE; LIPID STORAGE; LOW LIPID ACCUMULATION PHENOTYPE; MOLECULAR DYNAMICS; NONHUMAN; PHENOTYPE; PHENOTYPIC VARIATION; POX2 GENE; PROMOTER REGION; PROTEIN SYNTHESIS; RECOMBINANT GENE; REPORTER GENE; TRANSCRIPTION REGULATION; YARROWIA LIPOLYTICA; BIOREACTOR; BIOSYNTHESIS; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; YARROWIA;

BIOREACTORS; CARBON; CULTURE MEDIA; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GLUCOSE; GLYCEROL; LIPASE; OLEIC ACID; OLEIC ACIDS; PROMOTER REGIONS, GENETIC; RECOMBINANT PROTEINS; YARROWIA;

EID: 84988402519     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-016-0558-8     Document Type: Article

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