A Catalytic Role for C-H/π Interactions in Base Excision Repair by Bacillus cereus DNA Glycosylase AlkD

Journal of the American Chemical Society

Volumn 138, Issue 36, 2016, Pages 11485-11488

  Parsons, Zachary D ^a   Bland, Joshua M ^a   Mullins, Elwood A ^a   Eichman, Brandt F ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOLOGY; CHEMICAL BONDS; DNA; REPAIR;

AROMATIC SIDE CHAINS; BASE EXCISION REPAIRS; DNA GLYCOSYLASE; GENOMIC INTEGRITY; GLYCOSIDIC BOND CLEAVAGE; INTER-MOLECULAR FORCES; PROTEIN STRUCTURES; SUBSTRATE RECOGNITION;

BACILLUS CEREUS;

CARBON; DEOXYRIBOSE; DNA; DNA GLYCOSYLASE ALKD; DNA GLYCOSYLTRANSFERASE; HYDROGEN; UNCLASSIFIED DRUG; BACTERIAL DNA;

ARTICLE; BACILLUS CEREUS; CATALYSIS; DNA HELIX; ENZYME ACTIVE SITE; EXCISION REPAIR; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DNA INTERACTION; PROTEIN STRUCTURE; BIOCATALYSIS; CHEMISTRY; DNA REPAIR; ENZYMOLOGY; GENETICS; METABOLISM;

BACILLUS CEREUS; BIOCATALYSIS; DNA GLYCOSYLASES; DNA REPAIR; DNA, BACTERIAL;

EID: 84987819681     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.6b07399     Document Type: Article

References (26)

1. Friedberg, E. C.; Walker, G. C.; Siede, W.; Wood, R. D.; Schultz, R. A.; Ellenberger, T. DNA Repair and Mutagenesis, 2 nd ed.; ASM Press: Washington, D.C., 2006
2. Gates, K. S. Chem. Res. Toxicol. 2009, 22, 1747 10.1021/tx900242k
3. Kim, Y.-J.; Wilson, D. M., III Curr. Mol. Pharmacol. 2012, 5, 3 10.2174/1874467211205010003
4. Brooks, S. C.; Adhikary, S.; Rubinson, E. H.; Eichman, B. F. Biochim. Biophys. Acta, Proteins Proteomics 2013, 1834, 247 10.1016/j.bbapap.2012.10.005
5. Stivers, J. T.; Jiang, Y. L. Chem. Rev. 2003, 103, 2729 10.1021/cr010219b
6. Mullins, E. A.; Shi, R.; Parsons, Z. D.; Yuen, P. K.; David, S. S.; Igarashi, Y.; Eichman, B. F. Nature 2015, 527, 254 10.1038/nature15728
7. Wilson, K. A.; Kellie, J. L.; Wetmore, S. D. Nucleic Acids Res. 2014, 42, 6726 10.1093/nar/gku269
8. Wilson, K. A.; Wells, R. A.; Abendong, M. N.; Anderson, C. B.; Kung, R. W.; Wetmore, S. D. J. Biomol. Struct. Dyn. 2016, 34, 184-200 10.1080/07391102.2015.1013157
9. Faraldos, J. A.; Antonczak, A. K.; González, V.; Fullerton, R.; Tippmann, E. M.; Allemann, R. K. J. Am. Chem. Soc. 2011, 133, 13906 10.1021/ja205927u
10. Deligeorgopoulou, A.; Taylor, S. E.; Forcat, S.; Allemann, R. K. Chem. Commun. 2003, 2162 10.1039/b306867f
11. Mullins, E. A.; Rubinson, E. H.; Eichman, B. F. DNA Repair 2014, 13, 50 10.1016/j.dnarep.2013.10.009
12. O'Brien, P. J.; Ellenberger, T. Biochemistry 2003, 42, 12418 10.1021/bi035177v
13. Hendershot, J. M.; O'Brien, P. J. Nucleic Acids Res. 2014, 42, 12681 10.1093/nar/gku919
14. Klapacz, J.; Lingaraju, G. M.; Guo, H. H.; Shah, D.; Moar-Shoshani, A.; Loeb, L. A.; Samson, L. D. Mol. Cell 2010, 37, 843 10.1016/j.molcel.2010.01.038
15. Livingston, A. L.; Kundu, S.; Henderson Pozzi, M.; Anderson, D. W.; David, S. S. Biochemistry 2005, 44, 14179 10.1021/bi050976u
16. Faraldos, J. A.; Antonczak, A. K.; González, V.; Fullerton, R.; Tippmann, E. M.; Allemann, R. K. J. Am. Chem. Soc. 2011, 133, 13906 10.1021/ja205927u
17. Dinner, A. R.; Blackburn, G. M.; Karplus, M. Nature 2001, 413, 752 10.1038/35099587
18. Osborne, M. R.; Phillips, D. H. Chem. Res. Toxicol. 2000, 13, 257 10.1021/tx990182e
19. Ezaz-Nikpay, K.; Verdine, G. L. Chem. Biol. 1994, 1, 235 10.1016/1074-5521(94)90016-7
20. Hong, Y. J.; Tantillo, D. J. Chem. Sci. 2013, 4, 2512 10.1039/c3sc50571e
21. Nepal, B.; Scheiner, S. J. Phys. Chem. A 2014, 118, 9575 10.1021/jp5070598
22. Zhao, Y.; Cotelle, Y.; Sakai, N.; Matile, S. J. Am. Chem. Soc. 2016, 138, 4270 10.1021/jacs.5b13006
23. Mishra, B. K.; Deshmukh, M. M.; Venkatnarayan, R. J. Org. Chem. 2014, 79, 8599 10.1021/jo501251s
24. Wijmenga, S. S.; van Buuren, B. N. M. Prog. Nucl. Magn. Reson. Spectrosc. 1998, 32, 287 10.1016/S0079-6565(97)00023-X
25. Vandenbussche, S.; Diaz, D.; Fernandez-Alonso, M. C.; Pan, W.; Vincent, S. P.; Cuevas, G.; Canada, F. J.; Jimenez-Barbero, J.; Bartik, K. Chem.-Eur. J. 2008, 14, 7570 10.1002/chem.200800247
26. Mecozzi, S.; West, A. P.; Dougherty, D. A. Proc. Natl. Acad. Sci. U. S. A. 1996, 93, 10566 10.1073/pnas.93.20.10566