The PI3K/Akt/mTOR pathway regulates the replicative senescence of human VSMCs

Molecular and Cellular Biochemistry

Volumn 422, Issue 1-2, 2016, Pages 1-10

  Tan, Pan ^a   Wang, Yan Jiao ^a   Li, Shuang ^a   Wang, Yi ^a   He, Je Yu ^a   Chen, Yi Yin ^a   Deng, Hui Qian ^a   Huang, Wu ^a   Zhan, Jun Kun ^a   Liu, You Shuo ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

PI3K Akt mTOR; Replicative senescence; Vascular aging; Vascular smooth muscle cells

Indexed keywords

BETA GALACTOSIDASE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; PROTEIN P16; PROTEIN P53; RAPAMYCIN; S6 KINASE; SERINE; SUPEROXIDE DISMUTASE; TELOMERASE; THREONINE; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CELL AGING; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENESCENCE; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE CELL; CELL CULTURE; CYTOLOGY; GENETICS; METABOLISM; PHYSIOLOGY; SMOOTH MUSCLE CELL; VASCULAR SMOOTH MUSCLE;

CELL AGING; CELLS, CULTURED; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84987679571     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-016-2796-9     Document Type: Article

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