Isolation, purification, characterization and immunostimulatory activity of polysaccharides derived from American ginseng

Carbohydrate Polymers

Volumn 156, Issue , 2017, Pages 9-18

  Yu, Xiao Hong ^a   Liu, Ying ^a   Wu, Xian Ling ^a   Liu, Li Zhai ^a   Fu, Wei ^a   Song, Dan Dan ^a  

^a HARBIN UNIVERSITY OF COMMERCE   (China)

Author keywords

American ginseng; Characterization; Immunostimulatory activity; Polysaccharide; Purification

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; CELL PROLIFERATION; CHARACTERIZATION; GAS CHROMATOGRAPHY; GEL PERMEATION CHROMATOGRAPHY; NITRIC OXIDE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYSACCHARIDES; PURIFICATION; SCANNING ELECTRON MICROSCOPY; SPECTROSCOPIC ANALYSIS;

AMERICAN GINSENG; GEL-FILTRATION CHROMATOGRAPHY; IMMUNOMODULATORY ACTIVITIES; IMMUNOSTIMULATORY ACTIVITIES; INFRARED SPECTRUM; SPLENIC LYMPHOCYTE; STRUCTURAL CHARACTERISTICS; VIS SPECTROSCOPY;

CHROMATOGRAPHY;

NITRIC OXIDE; POLYSACCHARIDE;

ANIMAL; CELL CULTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECT; LYMPHOCYTE; MACROPHAGE; MALE; METABOLISM; MOUSE; PANAX; PHAGOCYTOSIS; SPLEEN;

ANIMALS; CELLS, CULTURED; LYMPHOCYTES; MACROPHAGES; MALE; MICE; NITRIC OXIDE; PANAX; PHAGOCYTOSIS; POLYSACCHARIDES; SPLEEN;

EID: 84986330155     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2016.08.092     Document Type: Article

References (42)

1. Assinewe, V.A., Arnason, J.T., Aubry, A., Mullin, J., Lemaire, I., Extractable polysaccharides of Panax quinquefolius L. (North American ginseng) root stimulate TNFα production by alveolar macrophages. Phytomedicine 9 (2002), 398–404.
2. Benhabiles, M.S., Drouiche, N., Lounici, H., Pauss, A., Mameri, N., Effect of shrimp chitosan coatings as affected by chitosan extraction processes on post-harvest quality of strawberries. Journal of Food Measurement and Characterization 4 (2013), 215–221.
3. Chokboribal, J., Tachaboonyakiat, W., Sangvanich, P., Ruangpornvisuti, V., Jettanacheawchankit, S., Thunyakitpisal, P., Deacetylation affects the physical properties and bioactivity of acemannan, an extracted polysaccharide from Aloe vera. Carbohydrate Polymers, 2015, 556–566.
4. Du, X.F., Jiang, C.Z., Wu, C.F., Won, E.K., Choung, S.Y., Synergistic immunostimulating activity of pidotimod and red ginseng acidic polysaccharide against cyclophosphamide-induced immunosuppression. Archives of Pharmacal Research 31 (2008), 1153–1159.
5. Fang, X., Yin, X., Yuan, G., Chen, X., Chemical and biological characterization of polysaccharides from the bark of Avicennia marina. European Food Research and Technology 241 (2015), 17–25.
6. Gao, H., Wang, F., Lien, E.J., Trousdale, M.D., Immunostimulating polysaccharides from Panax notoginseng. Pharmaceutical Research 8 (1996), 1196–1200.
7. Hu, H., Liang, H., Wu, Y., Isolation, purification and structural characterization of polysaccharide from Acanthopanax brachypus. Carbohydrate Polymers, 2015, 94–100.
8. Hwang, I., Ahn, G., Park, E., Ha, D., Song, J., Jee, Y., An acidic polysaccharide of Panax ginseng ameliorates experimental autoimmune encephalomyelitis and induces regulatory T cells. Immunology Letters 138 (2011), 169–178.
9. Jiang, H., Sun, P., He, J., Shao, P., Rapid purification of polysaccharides using novel radial flow ion-exchange by response surface methodology from Ganoderma lucidum. Food and Bioproducts Processing: Transactions of the Institution of Chemical Engineers Part C 1 (2012), 1–8.
10. Jin, M., Wang, Y., Xu, C., Lu, Z., Huang, M., Wang, Y., Preparation and biological activities of an exopolysaccharide produced by Enterobacter cloacae Z0206. Carbohydrate Polymers 3 (2010), 607–611.
11. Kouakou, K., Schepetkin, I.A., Yapi, A., Kirpotina, L.N., Jutila, M.A., Quinn, M.T., Immunomodulatory activity of polysaccharides isolated from Alchornea cordifolia. Journal of Ethnopharmacology 146 (2013), 232–242.
12. Lee, J., Tanikawa, T., Hayashi, K., Asagi, M., Kasahara, Y., Hayashi, T., Characterization and biological effects of two polysaccharides isolated from Acanthopanax sciadophylloides. Carbohydrate Polymers 116 (2015), 159–166.
13. Lemmon, H.R., Sham, J., Chau, L.A., Madrenas, J.J.M.M., High molecular weight polysaccharides are key immunomodulators in North American ginseng extracts: Characterization of the ginseng genetic signature in primary human immune cells. Journal of Ethnopharmacology 1 (2012), 1–13.
14. Li, C., Cai, J., Geng, J., Li, Y., Wang, Z., Li, R., Purification, characterization and anticancer activity of a polysaccharide from Panax ginseng. International Journal of Biological Macromolecules 51 (2012), 968–973.
15. Li, Q., Xie, Y., Su, J., Ye, Q., Jia, Z., Isolation and structural characterization of a neutral polysaccharide from the stems of Dendrobium densiflorum. International Journal of Biological Macromolecules 50 (2012), 1207–1211.
16. Liu, J., Luo, J., Sun, Y., Ye, H., Lu, Z., Zeng, X., A simple method for the simultaneous decoloration and deproteinization of crude levan extract from Paenibacillus polymyxa EJS-3 by macroporous resin. Bioresource Technology 15 (2010), 6077–6083.
17. Ma, X.L., Hao, C.Y., Lu, S.X., Sun, Y.X., Liu, J.Z., Liu, S.Y., Isolation and characterization of a bioactive polysaccharide from Panax quinquefolium L. Chemical Research in Chinese Universities 2 (1998), 143–146.
18. Maity, K., Kar Mandal, E., Maity, S., Gantait, S.K., Das, D., Maiti, S., et al. Structural characterization and study of immunoenhancing and antioxidant property of a novel polysaccharide isolated from the aqueous extract of a somatic hybrid mushroom of Pleurotus florida and Calocybe indica variety APK2. International Journal of Biological Macromolecules 48 (2011), 304–310.
19. Ming, Y., Qiu, T., Peng, W., Chen, W., Ye, Y., Lin, Y., Purification, characterization and hypoglycemic activity of extracellular polysaccharides from Lachnum calyculiforme. Carbohydrate Polymers 1 (2011), 285–290.
20. Mondal, S., Das, D., Roy, S.K., Islam, S.S., Isolation, purification and structural characterization of an acetylated heteroglycan from the unripe fruits of Manilkara zapota L. Carbohydrate Research 354 (2012), 74–78.
21. Mu, L.X., Zhu, L., Zhao, A.H., Zhou, M.M., Jia, W., Study on extraction and purification of polysaccharides from Astragalus membranaceus. Journal of Chinese Medicinal Materials 32 (2009), 1741–1745.
22. Pan, D., Wang, L., Chen, C., Teng, B., Wang, C., Xu, Z., et al. Structure characterization of a novel neutral polysaccharide isolated from Ganoderma lucidum fruiting bodies. Food Chemistry 135 (2012), 1097–1103.
23. Prozil, S.O., Costa, E.V., Evtuguin, D.V., Cruz Lopes, L.P., Domingues, M.R., Structural characterization of polysaccharides isolated from grape stalks of Vitis vinifera L. Carbohydrate Research 356 (2012), 252–259.
24. Shang, M., Zhang, X., Dong, Q., Yao, J., Liu, Q., Ding, K., Isolation and structural characterization of the water-extractable polysaccharides from Cassia obtusifolia seeds. Carbohydrate Polymers 90 (2012), 827–832.
25. Sudhamani, S.R., Tharanathan, R.N., Prasad, M.S., Isolation and characterization of an extracellular polysaccharide from Pseudomonas caryophylli CFR 1705. Carbohydrate Polymers 56 (2004), 423–427.
26. Sun, L., Peng, X., Sun, P., Shi, J., Yuan, X., Zhu, J., et al. Structural characterization and immunostimulatory activity of a novel linear α-(1 → 6)-D-glucan isolated from Panax ginseng C. A. Meyer. Glycoconjugate Journal 29 (2012), 357–364.
27. Tian, H., Yin, X., Zeng, Q., Zhu, L., Chen, J., Isolation, structure, and surfactant properties of polysaccharides from Ulva lactuca L. from South China Sea. International Journal of Biological Macromolecules 79 (2015), 577–582.
28. Wang, M., Jiang, C., Ma, L., Zhang, Z., Cao, L., Liu, J., et al. Preparation, preliminary characterization and immunostimulatory activity of polysaccharide fractions from the peduncles of Hovenia dulcis. Food Chemistry 138 (2013), 41–47.
29. Wang, L., Yao, Y., Sang, W., Yang, X., Ren, G., Structural features and immunostimulating effects of three acidic polysaccharides isolated from Panax quinquefolius. International Journal of Biological Macromolecules 80 (2015), 77–86.
30. Wang, Y., Huang, M., Sun, R., Pan, L., Extraction, characterization of a Ginseng fruits polysaccharide and its immune modulating activities in rats with Lewis lung carcinoma. Carbohydrate Polymers 127 (2015), 215–221.
31. Wilson, S.A., Wong, M.H., Stryjecki, C., De Boer, A., Lui, E.M., Mutch, D.M., Unraveling the adipocyte inflammomodulatory pathways activated by North American ginseng. International Journal of Obesity (London) 37 (2013), 350–356.
32. Yang, R., Meng, D., Song, Y., Li, J., Zhang, Y., Hu, X., et al. Simultaneous decoloration and deproteinization of crude polysaccharide from pumpkin residues by cross-linked polystyrene macroporous resin. Journal of Agricultural and Food Chemistry 34 (2012), 8450–8456.
33. Yang, W., Pei, F., Shi, Y., Zhao, L., Fang, Y., Hu, Q., Purification, characterization and anti-proliferation activity of polysaccharides from Flammulina velutipes. Carbohydrate Polymers 88 (2012), 474–480.
34. Yi, Y., Zhang, M., Liao, S., Zhang, R., Deng, Y., Wei, Z., et al. Structural features and immunomodulatory activities of polysaccharides of longan pulp. Carbohydrate Polymers 87 (2012), 636–643.
35. Yu, Z.H., Jin, C., Xin, M., He, J.M., Effect of Aloe vera polysaccharides on immunity and antioxidant activities in oral ulcer animal models. Carbohydrate Polymers 75 (2009), 307–311.
36. Yu, Z., Ming, G., Kaiping, W., Zhixiang, C., Liquan, D., Jingyu, L., et al. Structure, chain conformation and antitumor activity of a novel polysaccharide from Lentinus edodes. Fitoterapia 81 (2010), 1163–1170.
37. Yu, X.N., Yang, X.S., Cui, B., Wang, L.J., Ren, G.X., Antioxidant and immunoregulatory activity of alkali-extractable polysaccharides from North American ginseng. International Journal of Biological Macromolecules 42 (2014), 357–361.
38. Yu, Z., Liu, L., Xu, Y., Wang, L., Teng, X., Li, X., et al. Characterization and biological activities of a novel polysaccharide isolated from raspberry (Rubus idaeus L.) fruits. Carbohydrate Polymers 132 (2015), 180–186.
39. Zha, X., Luo, J., Luo, S., Jiang, S., Structure identification of a new immunostimulating polysaccharide from the stems of Dendrobium huoshanense. Carbohydrate Polymers 69 (2007), 86–93.
40. Zhang, S.P., Du, X.X., Zhou, Q.S., Jie, M., Hui, L., Study on deproteinization and decoloration in fucoidan. Advanced Materials Research 11 (2011), 62–66.
41. Zhang, L.H., Zhao, P., Meng, Q.H., Du, Y.P., Decolorization of limonium bicolor kunze (Bge.) polysaccharides by resins. Advanced Materials Research 978 (2014), 48–51.
42. Zheng, Y., Wang, W., Li, Y., Antitumor and immunomodulatory activity of polysaccharide isolated from Trametes orientalis. Carbohydrate Polymers 131 (2015), 248–254.