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Volumn 7, Issue 2, 2016, Pages

Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; REACTIVE OXYGEN METABOLITE; SHAB POTASSIUM CHANNEL;

EID: 84986253790     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2016.18     Document Type: Article
Times cited : (73)

References (41)
  • 1
    • 0025269152 scopus 로고
    • Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity
    • DeKosky ST, Scheff SW. Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity. Ann Neurol 1990; 27: 457-464.
    • (1990) Ann Neurol , vol.27 , pp. 457-464
    • DeKosky, S.T.1    Scheff, S.W.2
  • 2
    • 77954132249 scopus 로고    scopus 로고
    • Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks
    • Palop JJ, Mucke L. Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat Neurosci 2010; 13: 812-818.
    • (2010) Nat Neurosci , vol.13 , pp. 812-818
    • Palop, J.J.1    Mucke, L.2
  • 3
    • 77952484484 scopus 로고    scopus 로고
    • Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: Two faces of the same coin?
    • Palop JJ, Mucke L. Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin? Neuromolecular Med 2009; 12: 48-55.
    • (2009) Neuromolecular Med , vol.12 , pp. 48-55
    • Palop, J.J.1    Mucke, L.2
  • 4
    • 34548264782 scopus 로고    scopus 로고
    • Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
    • Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N et al. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron 2007; 55: 697-711.
    • (2007) Neuron , vol.55 , pp. 697-711
    • Palop, J.J.1    Chin, J.2    Roberson, E.D.3    Wang, J.4    Thwin, M.T.5    Bien-Ly, N.6
  • 5
    • 84861844315 scopus 로고    scopus 로고
    • Critical role of soluble amyloid-beta for early hippocampal hyperactivity in a mouse model of Alzheimer's disease
    • Busche MA, Chen X, Henning HA, Reichwald J, Staufenbiel M, Sakmann B et al. Critical role of soluble amyloid-beta for early hippocampal hyperactivity in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 2012; 109: 8740-8745.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 8740-8745
    • Busche, M.A.1    Chen, X.2    Henning, H.A.3    Reichwald, J.4    Staufenbiel, M.5    Sakmann, B.6
  • 7
    • 0033103708 scopus 로고    scopus 로고
    • Identification of the kv2.1K+ channel as a major component of the delayed rectifier K+ current in rat hippocampal neurons
    • Murakoshi H, Trimmer JS. Identification of the Kv2.1K+ channel as a major component of the delayed rectifier K+ current in rat hippocampal neurons. J Neurosci 1999; 19: 1728-1735.
    • (1999) J Neurosci , vol.19 , pp. 1728-1735
    • Murakoshi, H.1    Trimmer, J.S.2
  • 8
    • 66149095505 scopus 로고    scopus 로고
    • Regulation of intrinsic excitability in hippocampal neurons by activity-dependent modulation of the KV2.1 potassium channel
    • Mohapatra DP, Misonou H, Pan SJ, Held JE, Surmeier DJ, Trimmer JS. Regulation of intrinsic excitability in hippocampal neurons by activity-dependent modulation of the KV2.1 potassium channel. Channels (Austin) 2009; 3: 46-56.
    • (2009) Channels (Austin) , vol.3 , pp. 46-56
    • Mohapatra, D.P.1    Misonou, H.2    Pan, S.J.3    Held, J.E.4    Surmeier, D.J.5    Trimmer, J.S.6
  • 10
    • 84896294801 scopus 로고    scopus 로고
    • Cyclin e1 regulates kv2.1 channel phosphorylation and localization in neuronal ischemia
    • Shah NH, Schulien AJ, Clemens K, Aizenman TD, Hageman TM, Wills ZP et al. Cyclin e1 regulates Kv2.1 channel phosphorylation and localization in neuronal ischemia. J Neurosci 2014; 34: 4326-4331.
    • (2014) J Neurosci , vol.34 , pp. 4326-4331
    • Shah, N.H.1    Schulien, A.J.2    Clemens, K.3    Aizenman, T.D.4    Hageman, T.M.5    Wills, Z.P.6
  • 12
    • 84873670810 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the apoptotic effect of KCNB1K+ channel oxidation
    • Wu X, Hernandez-Enriquez B, Banas M, Xu R, Sesti F. Molecular mechanisms underlying the apoptotic effect of KCNB1K+ channel oxidation. J Biol Chem 2013; 288: 4128-4134.
    • (2013) J Biol Chem , vol.288 , pp. 4128-4134
    • Wu, X.1    Hernandez-Enriquez, B.2    Banas, M.3    Xu, R.4    Sesti, F.5
  • 13
    • 0029902166 scopus 로고    scopus 로고
    • Evidence of neuronal oxidative damage in Alzheimer's disease
    • Good PF, Werner P, Hsu A, Olanow CW, Perl DP. Evidence of neuronal oxidative damage in Alzheimer's disease. Am J Pathol 1996; 149: 21-28.
    • (1996) Am J Pathol , vol.149 , pp. 21-28
    • Good, P.F.1    Werner, P.2    Hsu, A.3    Olanow, C.W.4    Perl, D.P.5
  • 15
    • 0042697305 scopus 로고    scopus 로고
    • Triple-transgenic model of Alzheimer's disease with plaques And tangles: Intracellular abeta and synaptic dysfunction
    • Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction. Neuron 2003; 39: 409-421.
    • (2003) Neuron , vol.39 , pp. 409-421
    • Oddo, S.1    Caccamo, A.2    Shepherd, J.D.3    Murphy, M.P.4    Golde, T.E.5    Kayed, R.6
  • 16
    • 52249115856 scopus 로고    scopus 로고
    • Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
    • Busche MA, Eichhoff G, Adelsberger H, Abramowski D, Wiederhold KH, Haass C et al. Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease. Science 2008; 321: 1686-1689.
    • (2008) Science , vol.321 , pp. 1686-1689
    • Busche, M.A.1    Eichhoff, G.2    Adelsberger, H.3    Abramowski, D.4    Wiederhold, K.H.5    Haass, C.6
  • 17
    • 0029767876 scopus 로고    scopus 로고
    • Dynamics of ongoing activity: Explanation of the large variability in evoked cortical responses
    • Arieli A, Sterkin A, Grinvald A, Aertsen A. Dynamics of ongoing activity: explanation of the large variability in evoked cortical responses. Science 1996; 273: 1868-1871.
    • (1996) Science , vol.273 , pp. 1868-1871
    • Arieli, A.1    Sterkin, A.2    Grinvald, A.3    Aertsen, A.4
  • 18
    • 33845882729 scopus 로고    scopus 로고
    • Coordinated memory replay in the visual cortex and hippocampus during sleep
    • Ji D, Wilson MA. Coordinated memory replay in the visual cortex and hippocampus during sleep. Nat Neurosci 2007; 10: 100-107.
    • (2007) Nat Neurosci , vol.10 , pp. 100-107
    • Ji, D.1    Wilson, M.A.2
  • 19
    • 0028828515 scopus 로고
    • The mechanisms of generation and propagation of synchronized bursting in developing networks of cortical neurons
    • Maeda E, Robinson HP, Kawana A. The mechanisms of generation and propagation of synchronized bursting in developing networks of cortical neurons. J Neurosci 1995; 15: 6834-6845.
    • (1995) J Neurosci , vol.15 , pp. 6834-6845
    • Maeda, E.1    Robinson, H.P.2    Kawana, A.3
  • 20
    • 84856619952 scopus 로고    scopus 로고
    • Experimental analysis and computational modeling of interburst intervals in spontaneous activity of cortical neuronal culture
    • Gritsun T, le Feber J, Stegenga J, Rutten WL. Experimental analysis and computational modeling of interburst intervals in spontaneous activity of cortical neuronal culture. Biol Cybern 2011; 105: 197-210.
    • (2011) Biol Cybern , vol.105 , pp. 197-210
    • Gritsun, T.1    Le Feber, J.2    Stegenga, J.3    Rutten, W.L.4
  • 21
    • 25444487761 scopus 로고    scopus 로고
    • Imaging input and output of neocortical networks in vivo
    • Kerr JN, Greenberg D, Helmchen F. Imaging input and output of neocortical networks in vivo. Proc Natl Acad Sci USA 2005; 102: 14063-14068.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14063-14068
    • Kerr, J.N.1    Greenberg, D.2    Helmchen, F.3
  • 22
    • 34547100567 scopus 로고    scopus 로고
    • The functional microarchitecture of the mouse Barrel cortex
    • Sato TR, Gray NW, Mainen ZF, Svoboda K. The functional microarchitecture of the mouse barrel cortex. PLoS Biol 2007; 5: e189.
    • (2007) PLoS Biol , vol.5 , pp. e189
    • Sato, T.R.1    Gray, N.W.2    Mainen, Z.F.3    Svoboda, K.4
  • 23
    • 0033966807 scopus 로고    scopus 로고
    • Frequency-dependent regulation of rat hippocampal somato-dendritic excitability by the K+ channel subunit kv2.1
    • Du J, Haak LL, Phillips-Tansey E, Russell JT, McBain CJ. Frequency-dependent regulation of rat hippocampal somato-dendritic excitability by the K+ channel subunit Kv2.1. J Physiol 2000; 522: 19-31.
    • (2000) J Physiol , vol.522 , pp. 19-31
    • Du, J.1    Haak, L.L.2    Phillips-Tansey, E.3    Russell, J.T.4    McBain, C.J.5
  • 25
    • 79954596666 scopus 로고    scopus 로고
    • Reactive oxygen species in the regulation of synaptic plasticity and memory
    • Massaad CA, Klann E. Reactive oxygen species in the regulation of synaptic plasticity and memory. Antioxid Redox Signal 2010; 14: 2013-2054.
    • (2010) Antioxid Redox Signal , vol.14 , pp. 2013-2054
    • Massaad, C.A.1    Klann, E.2
  • 26
    • 3042808310 scopus 로고    scopus 로고
    • Messenger RNA and protein expression analysis of voltage-gated potassium channels in the brain of abeta(25-35)-treated rats
    • Pan Y, Xu X, Tong X, Wang X. Messenger RNA and protein expression analysis of voltage-gated potassium channels in the brain of Abeta(25-35)-treated rats. J Neurosci Res 2004; 77: 94-99.
    • (2004) J Neurosci Res , vol.77 , pp. 94-99
    • Pan, Y.1    Xu, X.2    Tong, X.3    Wang, X.4
  • 27
    • 0035814447 scopus 로고    scopus 로고
    • Dynamic localization and clustering of dendritic kv2.1 voltage-dependent potassium channels in developing hippocampal neurons
    • Antonucci DE, Lim ST, Vassanelli S, Trimmer JS. Dynamic localization and clustering of dendritic Kv2.1 voltage-dependent potassium channels in developing hippocampal neurons. Neuroscience 2001; 108: 69-81.
    • (2001) Neuroscience , vol.108 , pp. 69-81
    • Antonucci, D.E.1    Lim, S.T.2    Vassanelli, S.3    Trimmer, J.S.4
  • 28
    • 84881522811 scopus 로고    scopus 로고
    • ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors
    • Halasi M, Wang M, Chavan TS, Gaponenko V, Hay N, Gartel AL. ROS inhibitor N-acetyl-L-cysteine antagonizes the activity of proteasome inhibitors. Biochem J 2013; 454: 201-208.
    • (2013) Biochem J , vol.454 , pp. 201-208
    • Halasi, M.1    Wang, M.2    Chavan, T.S.3    Gaponenko, V.4    Hay, N.5    Gartel, A.L.6
  • 29
    • 78651278360 scopus 로고    scopus 로고
    • A perfect storm: Converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation
    • Noebels J. A perfect storm: converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation. Epilepsia 2011; 52: 39-46.
    • (2011) Epilepsia , vol.52 , pp. 39-46
    • Noebels, J.1
  • 31
    • 84860334015 scopus 로고    scopus 로고
    • Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model
    • Verret L, Mann EO, Hang GB, Barth AM, Cobos I, Ho K et al. Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell 2012; 149: 708-721.
    • (2012) Cell , vol.149 , pp. 708-721
    • Verret, L.1    Mann, E.O.2    Hang, G.B.3    Barth, A.M.4    Cobos, I.5    Ho, K.6
  • 33
    • 24644460177 scopus 로고    scopus 로고
    • Enhanced caffeine-induced ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease
    • Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM. Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease. J Neurochem 2005; 94: 1711-1718.
    • (2005) J Neurochem , vol.94 , pp. 1711-1718
    • Smith, I.F.1    Hitt, B.2    Green, K.N.3    Oddo, S.4    LaFerla, F.M.5
  • 34
    • 80155148269 scopus 로고    scopus 로고
    • The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease
    • McManus MJ, Murphy MP, Franklin JL. The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease. J Neurosci 2011; 31: 15703-15715.
    • (2011) J Neurosci , vol.31 , pp. 15703-15715
    • McManus, M.J.1    Murphy, M.P.2    Franklin, J.L.3
  • 35
    • 84872356165 scopus 로고    scopus 로고
    • Regulation of kv2.1 K(+) conductance by cell surface channel density
    • Fox PD, Loftus RJ, Tamkun MM. Regulation of Kv2.1 K(+) conductance by cell surface channel density. J Neurosci 2013; 33: 1259-1270.
    • (2013) J Neurosci , vol.33 , pp. 1259-1270
    • Fox, P.D.1    Loftus, R.J.2    Tamkun, M.M.3
  • 36
    • 0027196945 scopus 로고
    • Expression of kv2.1 delayed rectifier K+ channel isoforms in the developing rat brain
    • Trimmer JS Expression of Kv2.1 delayed rectifier K+ channel isoforms in the developing rat brain. FEBS Lett 1993; 324: 205-210.
    • (1993) FEBS Lett , vol.324 , pp. 205-210
    • Trimmer, J.S.1
  • 37
    • 51649089404 scopus 로고    scopus 로고
    • Dynamic regulation of the kv2.1 voltage-gated potassium channel during brain ischemia through neuroglial interaction
    • Misonou H, Thompson SM, Cai X. Dynamic regulation of the Kv2.1 voltage-gated potassium channel during brain ischemia through neuroglial interaction. J Neurosci 2008; 28: 8529-8538.
    • (2008) J Neurosci , vol.28 , pp. 8529-8538
    • Misonou, H.1    Thompson, S.M.2    Cai, X.3
  • 38
    • 0031938769 scopus 로고    scopus 로고
    • The K+ channel, kv2.1, is apposed to astrocytic processes and is associated with inhibitory postsynaptic membranes in hippocampal and cortical principal neurons and inhibitory interneurons
    • Du J, Tao-Cheng JH, Zerfas P, McBain CJ. The K+ channel, Kv2.1, is apposed to astrocytic processes and is associated with inhibitory postsynaptic membranes in hippocampal and cortical principal neurons and inhibitory interneurons. Neuroscience 1998; 84: 37-48.
    • (1998) Neuroscience , vol.84 , pp. 37-48
    • Du, J.1    Tao-Cheng, J.H.2    Zerfas, P.3    McBain, C.J.4
  • 39
    • 33747592823 scopus 로고    scopus 로고
    • Graded regulation of the kv2.1 potassium channel by variable phosphorylation
    • Park KS, Mohapatra DP, Misonou H, Trimmer JS. Graded regulation of the Kv2.1 potassium channel by variable phosphorylation. Science 2006; 313: 976-979.
    • (2006) Science , vol.313 , pp. 976-979
    • Park, K.S.1    Mohapatra, D.P.2    Misonou, H.3    Trimmer, J.S.4
  • 40
    • 0033514513 scopus 로고    scopus 로고
    • Preferential zn2+ influx through ca2 +-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production
    • Sensi SL, Yin HZ, Carriedo SG, Rao SS, Weiss JH. Preferential Zn2+ influx through Ca2 +-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production. Proc Natl Acad Sci USA 1999; 96: 2414-2419.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2414-2419
    • Sensi, S.L.1    Yin, H.Z.2    Carriedo, S.G.3    Rao, S.S.4    Weiss, J.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.