On the origins of three-dimensionality in drug-like molecules

Future Medicinal Chemistry

Volumn 8, Issue 14, 2016, Pages 1753-1767

  Meyers, Joshua ^a   Carter, Michael ^a   Mok, N Yi ^a   Brown, Nathan ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

drug like molecules; library enumeration; molecular shape; molecular three dimensionality; plane of best fit; principal moments of inertia; scaffolds; ternary density plots

Indexed keywords

HYDROGEN; MOLECULAR SCAFFOLD; DRUG; MOLECULAR LIBRARY;

ALGORITHM; ARTICLE; CHEMICAL STRUCTURE; DRUG CONFORMATION; DRUG DESIGN; DRUG LIKE MOLECULE; DRUG STRUCTURE; GEOMETRY; MATHEMATICAL ANALYSIS; MEDICINAL CHEMISTRY; MOLECULAR RECOGNITION; MOLECULAR THREE DIMENSIONALITY; MOLECULE; PHYSICAL CHEMISTRY; PRINCIPAL MOMENTS OF INERTIA; PRIORITY JOURNAL; STEREOISOMERISM; CHEMISTRY; HUMAN; MOLECULAR LIBRARY; SYNTHESIS;

CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; HUMANS; MOLECULAR STRUCTURE; PHARMACEUTICAL PREPARATIONS; SMALL MOLECULE LIBRARIES;

EID: 84986253756     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc-2016-0095     Document Type: Article

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