Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing

Stem Cells

Volumn 34, Issue 9, 2016, Pages 2429-2442

  Chinnadurai, Raghavan ^a,b   Copland, Ian B ^a,b,c   Garcia, Marco A ^c   Petersen, Christopher T ^a,b   Lewis, Christopher N ^a,b   Waller, Edmund K ^a,b,c   Kirk, Allan D ^d   Galipeau, Jacques ^a,b,c  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

actin; Autophagy; Cryopreservation; DMSO; Heat shock; Immune suppression; Indoleamine 2,3 dioxygenase; Mesenchymal stromal cells; T cell responses; Thawing

Indexed keywords

ACTIN; CASPASE INHIBITOR; CRYOPROTECTIVE AGENT; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; N METHYLTRYPTOPHAN; SERUM ALBUMIN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CONTACT; CELL LYSATE; CELL SURVIVAL; COCULTURE; COLD INJURY; CONTROLLED STUDY; CRYOPRESERVATION; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; DEGRANULATION; DEPOLYMERIZATION; EX VIVO STUDY; FILTERS AND MEMBRANES; FREEZE THAWING; HEAT SHOCK RESPONSE; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MESENCHYMAL STROMA CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; T LYMPHOCYTE; THROMBOCYTE; TISSUE DISTRIBUTION; TROPISM;

EID: 84985960374     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2415     Document Type: Article

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