Target organ specific activity of drosophila MRP (ABCC1) moderates developmental toxicity of methylmercury

Toxicological Sciences

Volumn 140, Issue 2, 2014, Pages 425-435

  Prince, Lisa ^a   Korbas, Malgorzata ^b,c   Davidson, Philip ^a   Broberg, Karin ^d   Rand, Matthew Dearborn ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b CANADIAN LIGHT SOURCE INC   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Drosophila; Fat body; Malpighian tubule; Methylmercury; Multidrug resistance like protein; X ray synchrotron fluorescence

Indexed keywords

METHYLMERCURY; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 3; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 1; TRANSCRIPTION FACTOR GAL4; ZINC ION; ABC TRANSPORTER; METHYLMERCURY DERIVATIVE; PRIMER DNA; TERATOGENIC AGENT;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEVELOPMENTAL TOXICITY; DISEASE PREDISPOSITION; DROSOPHILA; ENHANCER REGION; FRUIT FLY MODEL; GENE EXPRESSION; GENE SILENCING; GENETIC VARIABILITY; LARVAL DEVELOPMENT; MALPIGHIAN TUBULE; NERVE CELL; NONHUMAN; ANIMAL; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; LARVA; METABOLISM; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; DNA PRIMERS; DROSOPHILA; GENE KNOCKDOWN TECHNIQUES; LARVA; METHYLMERCURY COMPOUNDS; POLYMERASE CHAIN REACTION; TERATOGENS;

EID: 84984939468     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu095     Document Type: Article

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