Drosophila CYP6g1 and its human homolog CYP3A4 confer tolerance to methylmercury during development

Toxicology

Volumn 300, Issue 1-2, 2012, Pages 75-82

  Rand, Matthew D ^a   Lowe, Jessica A ^a   Mahapatra, Cecon T ^a,b  

^a UNIVERSITY OF VERMONT   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

CYP3A4; CYP6g1; Cytochrome P450; Drosophila; Methylmercury

Indexed keywords

CAFFEINE; CYTOCHROME P450; CYTOCHROME P450 3A4; CYTOCHROME P450 6G1; METHYLMERCURY; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN TOXICITY; CONTROLLED STUDY; DROSOPHILA; FEMALE; GENE EXPRESSION REGULATION; GENETIC RESISTANCE; LARVA; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; STRAIN DIFFERENCE; UPREGULATION; WILD TYPE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CONSERVED SEQUENCE; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; DRUG TOLERANCE; GENE EXPRESSION PROFILING; METHYLMERCURY COMPOUNDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 84863844183     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2012.06.001     Document Type: Article

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