IL-33 receptor-expressing regulatory t cells are highly activated, Th2 biased and suppress CD4 T Cell proliferation through IL-10 and TGFβ Release

PLoS ONE

Volumn 11, Issue 8, 2016, Pages

  Siede, Julia ^a,b   Fröhlich, Anja ^a,b   Datsi, Angeliki ^a,b   Hegazy, Ahmed N ^c,d   Varga, Domonkos V ^a,b   Holecska, Vivien ^a,b   Saito, Hirohisa ^e   Nakae, Susumu ^f,g   Löhning, Max ^a,b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b DEUTSCHES RHEUMA FORSCHUNGSZENTRUM   (Germany)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 33; INTERLEUKIN 33 RECEPTOR; INTERLEUKIN 5; INTERLEUKIN RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; GATA3 PROTEIN, MOUSE; IL10 PROTEIN, MOUSE; IL1RL1 PROTEIN, MOUSE; IL33 PROTEIN, MOUSE; INTERLEUKIN 1 RECEPTOR LIKE 1 PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; IN VITRO STUDY; LYMPHOCYTE PROLIFERATION; LYMPHOID ORGAN; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION; TH2 CELL; ANIMAL; C57BL MOUSE; CELL LINEAGE; CELL PROLIFERATION; CYTOLOGY; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION;

ANIMALS; CELL LINEAGE; CELL PROLIFERATION; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; IMMUNOPHENOTYPING; INTERLEUKIN-1 RECEPTOR-LIKE 1 PROTEIN; INTERLEUKIN-10; INTERLEUKIN-13; INTERLEUKIN-33; INTERLEUKIN-5; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA;

EID: 84984917650     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0161507     Document Type: Article

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