Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants

Toxicology

Volumn 368-369, Issue , 2016, Pages 69-79

  Stavreva, Diana A ^a   Varticovski, Lyuba ^a   Levkova, Ludmila ^b   George, Anuja A ^a   Davis, Luke ^a   Pegoraro, Gianluca ^a   Blazer, Vicki ^c   Iwanowicz, Luke ^c   Hager, Gordon L ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c LEETOWN SCIENCE CENTER   (United States)

Author keywords

BPA; EDCs; High throughput cell assay; TBBPA; TR

Indexed keywords

3,3',5' TRIIODOTHYRONINE; 4,4' ISOPROPYLIDENEDIPHENOL; ENDOCRINE DISRUPTOR; GLUCOCORTICOID RECEPTOR; GREEN FLUORESCENT PROTEIN; LIOTHYRONINE; THYROID HORMONE RECEPTOR BETA; TIRATRICOL; 3,3',5-TRIIODOTHYROACETIC ACID; BENZHYDRYL DERIVATIVE; PHENOL DERIVATIVE; POLLUTANT; POLYBROMINATED BIPHENYL; TETRABROMOBISPHENOL A;

ARTICLE; CELL ASSAY; CHIMERA; CONTAMINATION; ENVIRONMENTAL MONITORING; GENETIC TRANSCRIPTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MCF 7 CELL LINE; POLLUTANT; PRIORITY JOURNAL; WATER SAMPLING; ANALOGS AND DERIVATIVES; ANALYSIS; BIOASSAY; CELL NUCLEUS; CYTOPLASM; DRUG EFFECTS; GENE TRANSLOCATION; MCF-7 CELL LINE; METABOLISM;

BENZHYDRYL COMPOUNDS; BIOLOGICAL ASSAY; CELL NUCLEUS; CYTOPLASM; ENDOCRINE DISRUPTORS; ENVIRONMENTAL POLLUTANTS; GREEN FLUORESCENT PROTEINS; HUMANS; MCF-7 CELLS; PHENOLS; POLYBROMINATED BIPHENYLS; RECEPTORS, GLUCOCORTICOID; THYROID HORMONE RECEPTORS BETA; TRANSCRIPTION, GENETIC; TRANSLOCATION, GENETIC; TRIIODOTHYRONINE;

EID: 84984878633     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2016.08.012     Document Type: Article

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