Structural modeling of high-affinity thyroid receptor-ligand complexes

European Biophysics Journal

Volumn 39, Issue 11, 2010, Pages 1523-1536

  De Araujo, Alexandre Suman ^a   Martínez, Leandro ^b   De Paula Nicoluci, Ricardo ^a   Skaf, Munir S ^b   Polikarpov, Igor ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Binding free energy; High affinity thyromimetics; Molecular dynamics; Nuclear receptor; Thyroid hormone receptor; Thyromimetics receptor binding modes

Indexed keywords

LIGAND; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR ALPHA;

ARTICLE; CHEMISTRY; ENZYME SPECIFICITY; METABOLISM; MOLECULAR DYNAMICS; PROTEIN BINDING; PROTEIN CONFORMATION;

LIGANDS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, THYROID HORMONE; SUBSTRATE SPECIFICITY; THYROID HORMONE RECEPTORS ALPHA;

EID: 77957702554     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-010-0610-2     Document Type: Article

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