Quercetin stimulates mitochondrial apoptosis dependent on activation of endoplasmic reticulum stress in hepatic stellate cells

Pharmaceutical Biology

Volumn 54, Issue 12, 2016, Pages 3237-3243

  He, Liwei ^a   Hou, Xianbang ^a   Fan, Fangtian ^a   Wu, Hongyan ^b  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b Yancheng Health Vocational and Technical College   (China)

Author keywords

Bcl 2; Hepatic fibrosis; hepatocyte; salubrinal

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CALNEXIN; CASPASE 3; CASPASE 9; CYTOCHROME C; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MEMBRANE PROTEIN; MESSENGER RNA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; PROTEIN IRE1; PROTEIN PERK; QUERCETIN; SALUBRINAL; UNCLASSIFIED DRUG; ANTIOXIDANT;

ANIMAL CELL; ANTIFIBROTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; DRUG ACTIVITY; EC50; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIVER CELL; MITOCHONDRION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION; STELLATE CELL; TUNEL ASSAY; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; HEPATIC STELLATE CELL; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM STRESS; HEPATIC STELLATE CELLS; MITOCHONDRIA; QUERCETIN; RATS;

EID: 84984710842     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880209.2016.1223143     Document Type: Article

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