Effect of folic acid food fortification in Canada on congenital heart disease subtypes

Circulation

Volumn 134, Issue 9, 2016, Pages 647-655

  Liu, Shiliang ^a   Joseph, K S ^b,c   Luo, Wei ^a   León, Juan Andrés ^a   Lisonkova, Sarka ^b   Van Den Hof, Michiel ^d   Evans, Jane ^e   Lim, Ken ^b   Little, Julian ^f   Sauve, Reg ^g   Kramer, Michael S ^h  

^a PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d DALHOUSIE UNIVERSITY   (Canada)

^e UNIVERSITY OF MANITOBA   (Canada)

^f UNIVERSITY OF OTTAWA   (Canada)

^g UNIVERSITY OF CALGARY   (Canada)

^h MCGILL UNIVERSITY   (Canada)

Author keywords

association; folic acid; heart defects, congenital; primary prevention

Indexed keywords

FOLIC ACID;

AORTA COARCTATION; ARTICLE; CANADA; COHORT ANALYSIS; CONGENITAL HEART DISEASE; ENDOCARDIAL CUSHION DEFECT; FALLOT TETRALOGY; FORTIFIED FOOD; GESTATION PERIOD; GREAT VESSELS TRANSPOSITION; HEART ATRIUM SEPTUM DEFECT; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HYPOPLASTIC LEFT HEART SYNDROME; LIVE BIRTH; POPULATION RESEARCH; PREGNANCY TERMINATION; PREVALENCE; PRIORITY JOURNAL; RISK REDUCTION; STILLBIRTH; ADULT; BIRTH RATE; FEMALE; HEALTH SURVEY; HEART DEFECTS, CONGENITAL; MALE; NEWBORN; PREGNANCY; TREATMENT OUTCOME; TRENDS;

ADULT; BIRTH RATE; CANADA; COHORT STUDIES; FEMALE; FOLIC ACID; FOOD, FORTIFIED; HEART DEFECTS, CONGENITAL; HUMANS; INFANT, NEWBORN; MALE; POPULATION SURVEILLANCE; PREGNANCY; TREATMENT OUTCOME;

EID: 84984706702     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.116.022126     Document Type: Article

References (46)

1. Hoffman JI, Kaplan S, The incidence of congenital heart disease. J Am Coll Cardiol 2002 39 1890 1900
2. Dolk H, Loane M, Garne E, European Surveillance of Congenital Anomalies (EUROCAT) Working Group Congenital heart defects in Europe: prevalence and perinatal mortality, 2000 to 2005. Circulation 2011 123 841 849. doi: 10.1161/CIRCULATIONAHA.110.958405
3. Reller MD, Strickland MJ, Riehle-Colarusso T, Mahle WT, Correa A, Prevalence of congenital heart defects in metropolitan Atlanta, 1998-2005. J Pediatr 2008 153 807 813. doi: 10.1016/j.jpeds.2008.05.059
4. Oyen N, Poulsen G, Boyd HA, Wohlfahrt J, Jensen PK, Melbye M, National time trends in congenital heart defects, Denmark, 1977-2005. Am Heart J 2009 157 467 473.e1. doi: 10.1016/j.ahj.2008.10.017
5. Public Health Agency of Canada. Congenital anomalies in Canada 2013: a perinatal health surveillance report. http://www.phac-Aspc.gc.ca/ccasn-rcsac/cac-Acc-2013-eng.php. Accessed October 6, 2015
6. Botto LD, Lin AE, Riehle-Colarusso T, Malik S, Correa A, National Birth Defects Prevention Study Seeking causes: classifying and evaluating congenital heart defects in etiologic studies. Birth Defects Res A Clin Mol Teratol 2007 79 714 727. doi: 10.1002/bdra.20403
7. Jenkins KJ, Correa A, Feinstein JA, Botto L, Britt AE, Daniels SR, Elixson M, Warnes CA, Webb CL, Americann Heart Association Council on Cardiovascular Disease in the Young Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the Americann Heart Association Council on Cardiovascular Disease in the Young: endorsed by the Americann Academy of Pediatrics. Circulation 2007 115 2995 3014. doi: 10.1161/CIRCULATIONAHA.106.183216
8. Liu S, Joseph KS, Lisonkova S, Rouleau J, Van den Hof M, Sauve R, Kramer MS, Canadian Perinatal Surveillance System (Public Health Agency of Canada) Association between maternal chronic conditions and congenital heart defects: a population-based cohort study. Circulation 2013 128 583 589. doi: 10.1161/CIRCULATIONAHA.112.001054
9. Czeizel AE, Dudás I, Prevention of the first occurrence of neural-Tube defects by periconceptional vitamin supplementation. N Engl J Med 1992 327 1832 1835. doi: 10.1056/NEJM199212243272602
10. Czeizel AE, Periconceptional folic acid containing multivitamin supplementation. Eur J Obstet Gynecol Reprod Biol 1998 78 151 161
11. Czeizel AE, The primary prevention of birth defects: multivitamins or folic acid? Int J Med Sci 2004 1 50 61
12. Huhta JC, Linask K, Bailey L, Recent advances in the prevention of congenital heart disease. Curr Opin Pediatr 2006 18 484 489. doi: 10.1097/01.mop.0000245347.45336.d7
13. Bailey LB, Berry RJ, Folic acid supplementation and the occurrence of congenital heart defects, orofacial clefts, multiple births, and miscarriage. Am J Clin Nutr 2005 81 suppl 1213S 1217S
14. Botto LD, Olney RS, Erickson JD, Vitamin supplements and the risk for congenital anomalies other than neural tube defects. Am J Med Genet C Semin Med Genet 2004 125C 12 21. doi: 10.1002/ajmg.c.30004
15. Czeizel AE, Dudás I, Vereczkey A, Bánhidy F, Folate deficiency and folic acid supplementation: the prevention of neural-Tube defects and congenital heart defects. Nutrients 2013 5 4760 4775. doi: 10.3390/nu5114760
16. Shaw GM, Carmichael SL, Yang W, Lammer EJ, Periconceptional nutrient intakes and risks of conotruncal heart defects. Birth Defects Res A Clin Mol Teratol 2010 88 144 151. doi: 10.1002/bdra.20648
17. Scanlon KS, Ferencz C, Loffredo CA, Wilson PD, Correa-Villaseñor A, Khoury MJ, Willett WC, Preconceptional folate intake and malformations of the cardiac outflow tract: Baltimore-Washington Infant Study Group. Epidemiology 1998 9 95 98
18. Ionescu-Ittu R, Marelli AJ, Mackie AS, Pilote L, Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada. BMJ 2009 338 b1673
19. Robbins JM, Tilford JM, Bird TM, Cleves MA, Reading JA, Hobbs CA, Hospitalizations of newborns with folate-sensitive birth defects before and after fortification of foods with folic acid. Pediatrics 2006 118 906 915. doi: 10.1542/peds.2005-2784
20. van Beynum IM, Kapusta L, Bakker MK, den Heijer M, Blom HJ, de Walle HE, Protective effect of periconceptional folic acid supplements on the risk of congenital heart defects: a registry-based case-control study in the northern Netherlands. Eur Heart J 2010 31 464 471. doi: 10.1093/eurheartj/ehp479
21. Khoshnood B, Loane M, Garne E, Addor MC, Arriola L, Bakker M, Barisic I, Bianca S, Boyd P, Calzolari E, Doray B, Draper E, Gatt M, Haeusler M, Melve KK, Latos-Bielenska A, McDonnell B, Mullaney C, Nelen V, O'Mahony M, Pierini A, Queisser-Luft A, Randrianaivo H, Rankin J, Rissmann A, Salvador J, Tucker D, Verellen-Dumoulin C, Wellesley D, Zymak-Zakutnya N, Dolk H, Recent decrease in the prevalence of congenital heart defects in Europe. J Pediatr 2013 162 108 13.e2. doi: 10.1016/j.jpeds.2012.06.035
22. Leirgul E, Gildestad T, Nilsen RM, Fomina T, Brodwall K, Greve G, Vollset SE, Holmstrøm H, Tell GS, Øyen N, Periconceptional folic acid supplementation and infant risk of congenital heart defects in Norway 1999-2009. Paediatr Perinat Epidemiol 2015 29 391 400. doi: 10.1111/ppe.12212
23. Czeizel AE, Vereczkey A, Szabó I, Folic acid in pregnant women associated with reduced prevalence of severe congenital heart defects in their children: a national population-based case-control study. Eur J Obstet Gynecol Reprod Biol 2015 193 34 39. doi: 10.1016/j.ejogrb.2015.06.024
24. De Wals P, Tairou F, Van Allen MI, Uh SH, Lowry RB, Sibbald B, Evans JA, Van den Hof MC, Zimmer P, Crowley M, Fernandez B, Lee NS, Niyonsenga T, Reduction in neural-Tube defects after folic acid fortification in Canada. N Engl J Med 2007 357 135 142. doi: 10.1056/NEJMoa067103
25. Liu S, West R, Randell E, Longerich L, O'connor KS, Scott H, Crowley M, Lam A, Prabhakaran V, McCourt C, A comprehensive evaluation of food fortification with folic acid for the primary prevention of neural tube defects. BMC Pregnancy Childbirth 2004 4 20. doi: 10.1186/1471-2393-4-20
26. Liu S, Joseph KS, Kramer MS, Allen AC, Sauve R, Rusen ID, Wen SW, Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System Relationship of prenatal diagnosis and pregnancy termination to overall infant mortality in Canada. JAMA 2002 287 1561 1567
27. Joseph KS, Kinniburgh B, Hutcheon JA, Mehrabadi A, Basso M, Davies C, Lee L, Determinants of increases in stillbirth rates from 2000 to 2010. CMAJ 2013 185 E345 E351. doi: 10.1503/cmaj.121372
28. Auger N, Fraser WD, Healy-Profitós J, Arbour L, Association between preeclampsia and congenital heart defects. JAMA 2015 314 1588 1598. doi: 10.1001/jama.2015.12505
29. Brodwall K, Leirgul E, Greve G, Vollset SE, Holmstrøm H, Tell GS, Øyen N, Possible common aetiology behind maternal preeclampsia and congenital heart defects in the child: a Cardiovascular Diseases in Norway Project Study. Paediatr Perinat Epidemiol 2016 30 76 85. doi: 10.1111/ppe.12252
30. Public Health Agency of Canada Canadian Perinatal Health Report, 2008 Edition. 2008. http://www.phac-Aspc.gc.ca/publicat/2008/cphr-rspc/pdf/cphr-rspc08-eng.pdf. Accessed June 8, 2016
31. Joseph KS, Fahey J, Canadian Perinatal Surveillance System Validation of perinatal data in the Discharge Abstract Database of the Canadian Institute for Health Information. Chronic Dis Can 2009 29 96 100
32. Ray GJ, Folic acid food fortification in Canada. Nutr Res 2004 62 pt 2 S35 S39
33. Pierpont ME, Basson CT, Benson DW Jr, Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL, Americann Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young Genetic basis for congenital heart defects: current knowledge: a scientific statement from the Americann Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the Americann Academy of Pediatrics. Circulation 2007 115 3015 3038. doi: 10.1161/CIRCULATIONAHA.106.183056
34. Kuhn L, Davidson LL, Durkin MS, Use of Poisson regression and time series analysis for detecting changes over time in rates of child injury following a prevention program. Am J Epidemiol 1994 140 943 955
35. Esteve J, Benhamous E, Raymond L, Space-Time variations and group correlations. In: Statistical Methods in Cancer Research Volume 4, Descriptive Epidemiology 1994 Lyon, France IARC. IARC Sci Publ 128
36. Liu S, Joseph KS, Wen SW, Trends in fetal and infant deaths caused by congenital anomalies. Semin Perinatol 2002 26 268 276
37. Liu S, Joseph KS, Wen SW, Kramer MS, Marcoux S, Ohlsson A, Sauve R, Fetal and Infant Health Study Group of the Canadian Perinatal Surveillance System Secular trends in congenital anomaly-related fetal and infant mortality in Canada, 1985-1996. Am J Med Genet 2001 104 7 13
38. Yazdy MM, Honein MA, Xing J, Reduction in orofacial clefts following folic acid fortification of the U.S. grain supply. Birth Defects Res A Clin Mol Teratol 2007 79 16 23. doi: 10.1002/bdra.20319
39. Kim HJ, Fay MP, Feuer EJ, Midthune DN, Permutation tests for Joinpoint regression with applications to cancer rates. Stat Med 2000 19 335 351
40. National Cancer Institute, Department of Cancer Control and Population Sciences Joinpoint trend analysis software. http://surveillance.cancer.gov/joinpoint/. Accessed June 8, 2016
41. Turner LA, McCourt C, Folic acid fortification: what does it mean for patients and physicians? CMAJ 1998 158 773 776
42. Ray JG, Efficacy of Canadian folic acid food fortification. Food Nutr Bull 2008 29 suppl S225 S230
43. Herskind AM, Almind Pedersen D, Christensen K, Increased prevalence of congenital heart defects in monozygotic and dizygotic twins. Circulation 2013 128 1182 1188. doi: 10.1161/CIRCULATIONAHA.113.002453
44. Wang W, Wang Y, Gong F, Zhu W, Fu S, MTHFR C677T polymorphism and risk of congenital heart defects: evidence from 29 case-control and TDT studies. PLoS One 2013 8 e58041. Doi: 10.1371/journal.pone.0058041
45. Padmanabhan N, Jia D, Geary-Joo C, Wu X, Ferguson-Smith AC, Fung E, Bieda MC, Snyder FF, Gravel RA, Cross JC, Watson ED, Mutation in folate metabolism causes epigenetic instability and transgenerational effects on development. Cell 2013 155 81 93
46. Brown HK, Wilk P, Changes in smoking during pregnancy in Ontario, 1995 to 2010: results from the Canadian community health survey. J Obstet Gynaecol Can 2014 36 878 884