Periconceptional Folic Acid Supplementation and Infant Risk of Congenital Heart Defects in Norway 1999-2009

Paediatric and Perinatal Epidemiology

Volumn 29, Issue 5, 2015, Pages 391-400

  Leirgul, Elisabeth ^a,b   Gildestad, Trude ^a   Nilsen, Roy Miodini ^a,b   Fomina, Tatiana ^a   Brodwall, Kristoffer ^a   Greve, Gottfried ^a,b   Vollset, Stein Emil ^a,c   Holmstrøm, Henrik ^d   Tell, Grethe S ^a,c   Øyen, Nina ^a,b  

^a UNIVERSITY OF BERGEN   (Norway)

^b HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^c NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

cohort study; congenital heart defects; epidemiology; folic acid supplementation; Norway

Indexed keywords

AORTA COARCTATION; AORTA VALVE STENOSIS; ARTICLE; ATRIOVENTRICULAR SEPTAL DEFECT; CANADA; CARDIOVASCULAR DISEASE; CAUSE OF DEATH; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; DISEASE SEVERITY; EBSTEIN ANOMALY; EUROPE; FALLOT TETRALOGY; FOLIC ACID SUPPLEMENTATION; GREAT VESSELS TRANSPOSITION; HEART ATRIUM SEPTUM DEFECT; HEART LEFT VENTRICLE OUTFLOW TRACT OBSTRUCTION; HEART RIGHT VENTRICLE DOUBLE OUTLET; HEART SEPTUM DEFECT; HEART VENTRICLE SEPTUM; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HYPOPLASTIC LEFT HEART SYNDROME; LUNG VEIN DRAINAGE ANOMALY; MAJOR CLINICAL STUDY; NORWAY; PATENT DUCTUS ARTERIOSUS; PHENOTYPE; PREVALENCE; PROTEIN SYNTHESIS; PULMONARY VALVE ATRESIA; PULMONARY VALVE STENOSIS; RISK FACTOR; RISK REDUCTION; ADULT; DIETARY SUPPLEMENT; FEMALE; HEART DEFECTS, CONGENITAL; MALE; MATERNAL NUTRITION; NEWBORN; PREGNANCY; PREGNANT WOMAN; PREPREGNANCY CARE; PROSPECTIVE STUDY; REGISTER; TIME FACTOR;

FOLIC ACID;

ADULT; DIETARY SUPPLEMENTS; FEMALE; FOLIC ACID; HEART DEFECTS, CONGENITAL; HUMANS; INFANT, NEWBORN; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; NORWAY; PRECONCEPTION CARE; PREGNANCY; PREGNANT WOMEN; PROSPECTIVE STUDIES; REGISTRIES; RISK FACTORS; TIME FACTORS;

EID: 84938963290     PISSN: 02695022     EISSN: 13653016     Source Type: Journal    
DOI: 10.1111/ppe.12212     Document Type: Article

References (25)

1. Hoffman JI, Kaplan S,. The incidence of congenital heart disease. Journal of the American College of Cardiology 2002; 39: 1890-1900.
2. Botto LD, Lin AE, Riehle-Colarusso T, Malik S, Correa A,. Seeking causes: classifying and evaluating congenital heart defects in etiologic studies. Birth Defects Research. Part A, Clinical and Molecular Teratology 2007; 79: 714-727.
3. Leirgul E, Fomina T, Brodwall K, Greve G, Holmstrom H, Vollset SE, etal. Birth prevalence of congenital heart defects in Norway 1994-2009-a nationwide study. American Heart Journal 2014; 168: 956-964.
4. Øyen N, Poulsen G, Boyd HA, Wohlfahrt J, Jensen PK, Melbye M,. National time trends in congenital heart defects, Denmark, 1977-2005. American Heart Journal 2009; 157: 467-473 e461.
5. Bjornard K, Riehle-Colarusso T, Gilboa SM, Correa A,. Patterns in the prevalence of congenital heart defects, metropolitan Atlanta, 1978 to 2005. Birth Defects Research. Part A, Clinical and Molecular Teratology 2013; 97: 87-94.
6. Ionescu-Ittu R, Marelli AJ, Mackie AS, Pilote L,. Prevalence of severe congenital heart disease after folic acid fortification of grain products: time trend analysis in Quebec, Canada. BMJ (Clinical Research Ed.) 2009; 338: b1673.
7. Khoshnood B, Loane M, Garne E, Addor MC, Arriola L, Bakker M, etal. Recent decrease in the prevalence of congenital heart defects in Europe. Journal of Pediatrics 2013; 162: 108-113 e102.
8. Milunsky A, Jick H, Jick SS, Bruell CL, MacLaughlin DS, Rothman KJ, etal. Multivitamin/folic acid supplementation in early pregnancy reduces the prevalence of neural tube defects. JAMA: The Journal of the American Medical Association 1989; 262: 2847-2852.
9. Czeizel AE, Dudas I,. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. New England Journal of Medicine 1992; 327: 1832-1835.
10. Daltveit AK, Vollset SE, Lande B, Øien H,. Changes in knowledge and attitudes of folate, and use of dietary supplements among women of reproductive age in Norway 1998-2000. Scandinavian Journal of Public Health 2004; 32: 264-271.
11. Shaw GM, O'Malley CD, Wasserman CR, Tolarova MM, Lammer EJ,. Maternal periconceptional use of multivitamins and reduced risk for conotruncal heart defects and limb deficiencies among offspring. American Journal of Medical Genetics 1995; 59: 536-545.
12. Czeizel AE,. Periconceptional folic acid containing multivitamin supplementation. European Journal of Obstetrics, Gynecology, and Reproductive Biology 1998; 78: 151-161.
13. van Beynum IM, Kapusta L, Bakker MK, den Heijer M, Blom HJ, de Walle HE,. Protective effect of periconceptional folic acid supplements on the risk of congenital heart defects: a registry-based case-control study in the northern Netherlands. European Heart Journal 2010; 31: 464-471.
14. Csaky-Szunyogh M, Vereczkey A, Kosa Z, Gerencser B, Czeizel AE,. Risk and protective factors in the origin of conotruncal defects of heart-a population-based case-control study. American Journal of Medical Genetics. Part A 2013; 161A: 2444-2452.
15. Bedard T, Lowry RB, Sibbald B, Harder JR, Trevenen C, Horobec V, etal. Folic acid fortification and the birth prevalence of congenital heart defect cases in Alberta, Canada. Birth Defects Research. Part A, Clinical and Molecular Teratology 2013; 97: 564-570.
16. Botto LD, Lisi A, Bower C, Canfield MA, Dattani N, De Vigan C, etal. Trends of selected malformations in relation to folic acid recommendations and fortification: an international assessment. Birth Defects Research. Part A, Clinical and Molecular Teratology 2006; 76: 693-705.
17. Irgens LM,. The Medical Birth Registry of Norway. Epidemiological research and surveillance throughout 30 years. Acta Obstetricia et Gynecologica Scandinavica 2000; 79: 435-439.
18. Hagemo PS,. BERTE-a database for children with congenital heart defects. Studies in Health Technology and Informatics 1994; 14: 98-101.
19. Sulo GIJ, Vollset SE, Nygård O, Øyen N, Tell GS,. Cardiovascular disease and diabetes mellitus in Norway during 1994-2009 CVDNOR-a nationwide research project. Norwegian journal of epidemiology. 2013; 23: 101-107.
20. Statistics Norway. Available from http://www.ssb.no/en/forside. [last accessed 20 July 2015].
21. Sengpiel V, Bacelis J, Myhre R, Myking S, Devold Pay A, Haugen M, etal. Folic acid supplementation, dietary folate intake during pregnancy and risk for spontaneous preterm delivery: a prospective observational cohort study. BMC Pregnancy and Childbirth 2014; 14: 375.
22. Li X, Li S, Mu D, Liu Z, Li Y, Lin Y, etal. The association between periconceptional folic acid supplementation and congenital heart defects: a case-control study in China. Preventive Medicine 2013; 56: 385-389.
23. Roth C, Bjørke-Monsen AL, Reichborn-Kjennerud T, Nilsen RM, Smith GD, Stoltenberg C, etal. Use of folic acid supplements in early pregnancy in relation to maternal plasma levels in week 18 of pregnancy. Molecular Nutrition and Food Research 2013; 57: 653-660.
24. Mikael LG, Deng L, Paul L, Selhub J, Rozen R,. Moderately high intake of folic acid has a negative impact on mouse embryonic development. Birth Defects Research. Part A, Clinical and Molecular Teratology 2013; 97: 47-52.
25. Suren P, Roth C, Bresnahan M, Haugen M, Hornig M, Hirtz D, etal. Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. JAMA: The Journal of the American Medical Association 2013; 309: 570-577.