ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling

Molecular and Cellular Neuroscience

Volumn 76, Issue , 2016, Pages 52-58

  Goode, Alice ^a   Rea, Sarah ^b,c   Sultana, Melanie ^b,c   Shaw, Barry ^a   Searle, Mark S ^a   Layfield, Robert ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c SIR CHARLES GAIRDNER HOSPITAL   (Australia)

Author keywords

ALS FTLD; Keap1 Nrf2; Oxidative stress; SQSTM1 p62

Indexed keywords

CELL PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LC3B PROTEIN; PROTEIN P62; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; KEAP1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; PROTEIN BINDING; SEQUESTOSOME 1; SQSTM1 PROTEIN, HUMAN;

AMYOTROPHIC LATERAL SCLEROSIS; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CONTROLLED STUDY; FRONTOTEMPORAL DEMENTIA; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; KEAP1 INTERACTING REGION; MISSENSE MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SQSTM1 GENE; BINDING SITE; CHEMISTRY; DNA RESPONSIVE ELEMENT; GENETICS; HEK293 CELL LINE; METABOLISM;

AMYOTROPHIC LATERAL SCLEROSIS; BINDING SITES; FRONTOTEMPORAL LOBAR DEGENERATION; HEK293 CELLS; HUMANS; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; MUTATION, MISSENSE; NF-E2-RELATED FACTOR 2; PROTEIN BINDING; RESPONSE ELEMENTS; SEQUESTOSOME-1 PROTEIN; SIGNAL TRANSDUCTION;

EID: 84984626892     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2016.08.004     Document Type: Article

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