-
1
-
-
33644837764
-
Early signs of motoneuron vulnerability in a disease model system: Characterization of transverse slice cultures of spinal cord isolated from embryonic ALS mice
-
DOI 10.1016/j.neuroscience.2005.12.009, PII S0306452205013941
-
Avossa D, Grandolfo M, Mazzarol F, et al: Early signs of motoneuron vulnerability in a disease model system: characterization of transverse slice cultures of spinal cord isolated from embryonic ALS mice. Neuroscience 138: 1179-1194, 2006. (Pubitemid 43363536)
-
(2006)
Neuroscience
, vol.138
, Issue.4
, pp. 1179-1194
-
-
Avossa, D.1
Grandolfo, M.2
Mazzarol, F.3
Zatta, M.4
Ballerini, L.5
-
2
-
-
78649288936
-
Timelines in the diagnostic evaluation of people with suspected amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) - A 20-year review: Can we do better?
-
Mitchell JD, Callagher P, Gardham J, et al: Timelines in the diagnostic evaluation of people with suspected amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND) - a 20-year review: can we do better? Amyotroph Lateral Scler 11: 537-541, 2010.
-
(2010)
Amyotroph Lateral Scler
, vol.11
, pp. 537-541
-
-
Mitchell, J.D.1
Callagher, P.2
Gardham, J.3
-
3
-
-
79952486262
-
Amyotrophic lateral sclerosis
-
Kiernan MC, Vucic S, Cheah BC, et al: Amyotrophic lateral sclerosis. Lancet 377: 942-955, 2011.
-
(2011)
Lancet
, vol.377
, pp. 942-955
-
-
Kiernan, M.C.1
Vucic, S.2
Cheah, B.C.3
-
4
-
-
79954608945
-
Emerging targets and treatments in amyotrophic lateral sclerosis
-
Zinman L and Cudkowicz M. Emerging targets and treatments in amyotrophic lateral sclerosis. Lancet Neurology 10: 481-490, 2011.
-
(2011)
Lancet Neurology
, vol.10
, pp. 481-490
-
-
Zinman, L.1
Cudkowicz, M.2
-
5
-
-
75149155060
-
Oxidative stress in ALS: Key role in motor neuron injury and therapeutic target
-
Barber SC and Shaw PJ: Oxidative stress in ALS: key role in motor neuron injury and therapeutic target. Free Radical Biol Med 48: 629-641, 2010.
-
(2010)
Free Radical Biol Med
, vol.48
, pp. 629-641
-
-
Barber, S.C.1
Shaw, P.J.2
-
6
-
-
84867320492
-
Nrf2/ARE signaling pathway: Key mediator in oxidative stress and potential therapeutic target in ALS
-
Petri S, Körner S and Kiaei M: Nrf2/ARE signaling pathway: key mediator in oxidative stress and potential therapeutic target in ALS. Neurol Res Int 2012: 878030, 2012.
-
(2012)
Neurol Res Int
, vol.2012
, pp. 878030
-
-
Petri, S.1
Körner, S.2
Kiaei, M.3
-
8
-
-
0037022339
-
Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS)
-
DOI 10.1073/pnas.032539299
-
Howland DS, Liu J, She Y, et al: Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS). Proc Natl Acad Sci USA 99: 1604-1609, 2002. (Pubitemid 34136539)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.3
, pp. 1604-1609
-
-
Howland, D.S.1
Liu, J.2
She, Y.3
Goad, B.4
Maragakis, N.J.5
Kim, B.6
Erickson, J.7
Kulik, J.8
DeVito, L.9
Psaltis, G.10
DeGennaro, L.J.11
Cleveland, D.W.12
Rothstein, J.D.13
-
9
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
Gurney ME, Pu H, Chiu AY, et al: Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 264: 1772-1775, 1994. (Pubitemid 24227760)
-
(1994)
Science
, vol.264
, Issue.5166
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal, C.M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.-X.10
Chen, W.11
Zhai, P.12
Sufit, R.L.13
Siddique, T.14
-
11
-
-
78751703950
-
Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
-
Taguchi K, Motohashi H and Yamamoto M: Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution. Genes Cells 16: 123-140, 2011.
-
(2011)
Genes Cells
, vol.16
, pp. 123-140
-
-
Taguchi, K.1
Motohashi, H.2
Yamamoto, M.3
-
12
-
-
70349333698
-
The Nrf2-ARE cytoprotective pathway in astrocytes
-
Vargas MR and Johnson JA: The Nrf2-ARE cytoprotective pathway in astrocytes. Expert Rev Mol Med 11: e17, 2009.
-
(2009)
Expert Rev Mol Med
, vol.11
-
-
Vargas, M.R.1
Johnson, J.A.2
-
13
-
-
81855204961
-
Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation
-
Hybertson BM, Gao B, Bose SK and McCord JM: Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation. Mol Aspects Med 32: 234-246, 2011.
-
(2011)
Mol Aspects Med
, vol.32
, pp. 234-246
-
-
Hybertson, B.M.1
Gao, B.2
Bose, S.K.3
McCord, J.M.4
-
14
-
-
27644485874
-
Oxidative stress in brain aging, neurodegenerative and vascular diseases: An overview
-
DOI 10.1016/j.jchromb.2005.04.023, PII S1570023205003041, Analysis of Antioxidants and Biomarkers of Oxidative Stress
-
Mariani E, Polidori MC, Cherubini A and Mecocci P: Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J Chromatogr B Analyt Technol Biomed Life Sci 827: 65-75, 2005. (Pubitemid 41551598)
-
(2005)
Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
, vol.827
, Issue.1
, pp. 65-75
-
-
Mariani, E.1
Polidori, M.C.2
Cherubini, A.3
Mecocci, P.4
-
15
-
-
0035955478
-
Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients
-
DOI 10.1016/S0006-8993(01)02926-2, PII S0006899301029262
-
Shibata N, Nagai R, Uchida K, et al: Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients. Brain Res 917: 97-104, 2001. (Pubitemid 32972133)
-
(2001)
Brain Research
, vol.917
, Issue.1
, pp. 97-104
-
-
Shibata, N.1
Nagai, R.2
Uchida, K.3
Horiuchi, S.4
Yamada, S.5
Hirano, A.6
Kawaguchi, M.7
Yamamoto, T.8
Sasaki, S.9
Kobayashi, M.10
-
16
-
-
58149232639
-
Nuclear erythroid 2-related factor 2-antioxidative response element signaling pathway in motor cortex and spinal cord in amyotrophic lateral sclerosis
-
Sarlette A, Krampfl K, Grothe C, et al: Nuclear erythroid 2-related factor 2-antioxidative response element signaling pathway in motor cortex and spinal cord in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 67: 1055-1062, 2008.
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, pp. 1055-1062
-
-
Sarlette, A.1
Krampfl, K.2
Grothe, C.3
-
17
-
-
34447633192
-
Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis
-
DOI 10.1523/JNEUROSCI.0823-07.2007
-
Pehar M, Vargas MR, Robinson KM, et al: Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. J Neurosci 27: 7777-7785, 2007. (Pubitemid 47093805)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.29
, pp. 7777-7785
-
-
Pehar, M.1
Vargas, M.R.2
Robinson, K.M.3
Cassina, P.4
Diaz-Amarilla, P.J.5
Hagen, T.M.6
Radi, R.7
Barbeito, L.8
Beckman, J.S.9
-
18
-
-
79957959973
-
Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis
-
Neymotin A, Calingasan NY, Wille E, et al: Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radic Biol Med 51: 88-96, 2011.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 88-96
-
-
Neymotin, A.1
Calingasan, N.Y.2
Wille, E.3
-
19
-
-
77957237159
-
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
-
Malhotra D, Portales-Casamar E, Singh A, et al: Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res 38: 5718-5734, 2010.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 5718-5734
-
-
Malhotra, D.1
Portales-Casamar, E.2
Singh, A.3
-
21
-
-
2142655894
-
NAD(P)H:quinone oxidoreductase 1: Role as a superoxide scavenger
-
DOI 10.1124/mol.65.5.1238
-
Siegel D, Gustafson DL, Dehn DL, et al: NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger. Mol Pharmacol 65: 1238-1247, 2004. (Pubitemid 38543494)
-
(2004)
Molecular Pharmacology
, vol.65
, Issue.5
, pp. 1238-1247
-
-
Siegel, D.1
Gustafson, D.L.2
Dehn, D.L.3
Han, J.Y.4
Boonchoong, P.5
Berliner, L.J.6
Ross, D.7
-
22
-
-
79954424076
-
Nrf2: Control of sensitivity to carcinogens
-
Slocum SL and Kensler TW: Nrf2: control of sensitivity to carcinogens. Arch Toxicol 85: 273-284, 2011.
-
(2011)
Arch Toxicol
, vol.85
, pp. 273-284
-
-
Slocum, S.L.1
Kensler, T.W.2
-
23
-
-
84873931664
-
Absence of Nrf2 or its selective overexpression in neurons and muscle does not affect survival in ALS-linked mutant hSOD1 mouse models
-
Vargas MR, Burton NC, Kutzke J, et al: Absence of Nrf2 or its selective overexpression in neurons and muscle does not affect survival in ALS-linked mutant hSOD1 mouse models. PLoS One 8: e56625, 2013.
-
(2013)
PLoS One
, vol.8
-
-
Vargas, M.R.1
Burton, N.C.2
Kutzke, J.3
-
24
-
-
60849115271
-
Neuroprotective potential of phase II enzyme inducer diallyl trisulfide
-
Sun MM, Bu H, Li B, et al: Neuroprotective potential of phase II enzyme inducer diallyl trisulfide. Neurol Res 31: 23-27, 2009.
-
(2009)
Neurol Res
, vol.31
, pp. 23-27
-
-
Sun, M.M.1
Bu, H.2
Li, B.3
-
25
-
-
77953537441
-
Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease
-
Stack C, Ho D, Wille E, et al: Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease. Free Radic Biol Med 49: 147-158, 2010.
-
(2010)
Free Radic Biol Med
, vol.49
, pp. 147-158
-
-
Stack, C.1
Ho, D.2
Wille, E.3
|