E-selectin inhibition mitigates splenic HSC activation and myelopoiesis in hypercholesterolemic mice with myocardial infarction

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 9, 2016, Pages 1802-1808

  Dutta, Partha ^a   Hoyer, Friedrich Felix ^a   Sun, Yuan ^a   Iwamoto, Yoshiko ^a   Tricot, Benoit ^a   Weissleder, Ralph ^a,b   Magnani, John L ^c   Swirski, Filip K ^a   Nahrendorf, Matthias ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c GlycoMimetics   (United States)

Author keywords

Atherosclerosis; E selectin; HSC; Myelopoiesis; Myocardial infarction

Indexed keywords

ANTIINFLAMMATORY AGENT; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GMI 1271; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; APOLIPOPROTEIN E;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AORTA ATHEROSCLEROSIS; ARTICLE; ATHEROSCLEROTIC PLAQUE; BONE MARROW CELL; CARDIOVASCULAR MAGNETIC RESONANCE; CELL ACTIVATION; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DRUG POTENCY; EXTRAMEDULLARY HEMATOPOIESIS; HEART INFARCTION; HEART INFARCTION SIZE; HEMATOPOIETIC STEM CELL; HYPERCHOLESTEROLEMIA; INFLAMMATION; MOUSE; MOUSE MODEL; MYELOPOIESIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SPLEEN; ANIMAL; AORTIC DISEASES; ATHEROSCLEROSIS; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; FIBROSIS; GENETICS; KNOCKOUT MOUSE; LIPID DIET; MALE; METABOLISM; MYOCARDIAL INFARCTION; NECROSIS; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; AORTIC DISEASES; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CELL PROLIFERATION; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; E-SELECTIN; FIBROSIS; HEMATOPOIETIC STEM CELLS; HYPERCHOLESTEROLEMIA; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOPOIESIS; MYOCARDIAL INFARCTION; NECROSIS; PLAQUE, ATHEROSCLEROTIC; SIGNAL TRANSDUCTION; SPLEEN;

EID: 84983802918     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.307519     Document Type: Article

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