Targeting interleukin-1β reduces leukocyte production after acute myocardial infarction

Circulation

Volumn 132, Issue 20, 2015, Pages 1880-1890

  Sager, Hendrik B ^a   Heidt, Timo ^a   Hulsmans, Maarten ^a   Dutta, Partha ^a   Courties, Gabriel ^a   Sebas, Matthew ^a   Wojtkiewicz, Gregory R ^a   Tricot, Benoit ^a   Iwamoto, Yoshiko ^a   Sun, Yuan ^a   Weissleder, Ralph ^b   Libby, Peter ^c   Swirski, Filip K ^a   Nahrendorf, Matthias ^a  

^a Center for Systems Biology   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

hematopoiesis; hematopoietic stem cells; interleukin 1 ; myocardial infarction

Indexed keywords

APOLIPOPROTEIN E; CELL ADHESION MOLECULE; INTERLEUKIN 1 ANTIBODY; INTERLEUKIN 1 BETA ANTIBODY; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; MESSENGER RNA; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; RECOMBINANT PROTEIN;

ACUTE HEART INFARCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW STROMA CELL; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY LIGATION; FEMALE; HEART FUNCTION; HEMATOPOIETIC STEM CELL; HUMAN; LEUKOCYTE; LEUKOCYTOSIS; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARABIOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; STEADY STATE; 129 MOUSE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DRUG DELIVERY SYSTEM; DRUG EFFECTS; KNOCKOUT MOUSE; METABOLISM; MYOCARDIAL INFARCTION; PATHOLOGY; PHYSIOLOGY; PROCEDURES; TRANSGENIC MOUSE;

ANIMALS; CELL PROLIFERATION; DRUG DELIVERY SYSTEMS; HEMATOPOIETIC STEM CELLS; INTERLEUKIN-1BETA; LEUKOCYTES; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MYOCARDIAL INFARCTION; RECOMBINANT PROTEINS;

EID: 84947487872     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.115.016160     Document Type: Article

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