Vascular niche E-selectin regulates hematopoietic stem cell dormancy, self renewal and chemoresistance

Nature Medicine

Volumn 18, Issue 11, 2012, Pages 1651-1657

  Winkler, Ingrid G ^a   Barbier, Valérie ^a   Nowlan, Bianca ^a   Jacobsen, Rebecca N ^a,b   Forristal, Catherine E ^a   Patton, John T ^c   Magnani, John L ^c   Lévesque, Jean Pierre ^a,b  

^a MATER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c GlycoMimetics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1 ANTAGONIST; FLUOROURACIL; GLYCOPROTEIN P INHIBITOR; GMI 1070; HYDROXYUREA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BONE MARROW SUPPRESSION; CANCER RESISTANCE; CELL CYCLE; CELL FATE; CELL MATURATION; CELL PROLIFERATION; CELL PROTECTION; CELL RENEWAL; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IRRADIATION; MICROENVIRONMENT; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL NICHE;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL SURVIVAL; E-SELECTIN; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HYDROXYUREA; LIGANDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; RADIATION;

MUS;

EID: 84869155711     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2969     Document Type: Article

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