Molecular mechanisms involving sigma-1 receptor in cell apoptosis of BV-2 microglial cells induced by methamphetamine

CNS and Neurological Disorders - Drug Targets

Volumn 15, Issue 7, 2016, Pages 857-865

  Shen, Kai ^a   Zhang, Yuan ^a   Lv, Xuan ^a   Chen, Xufeng ^b   Zhou, Rongbin ^c   Nguyen, Lan K ^d   Wu, Xiaodong ^a   Yao, Honghong ^a,e  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^d MONASH UNIVERSITY   (Australia)

^e SOUTHEAST UNIVERSITY   (China)

Author keywords

Apoptosis; Methamphetamine; Microglia; 1R

Indexed keywords

CASPASE 3; CASPASE 9; METHAMPHETAMINE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; SIGMA 1 OPIATE RECEPTOR; CASPASE; PROTEIN KINASE B; PROTEIN P53; SIGMA OPIATE RECEPTOR; SIGMA-1 RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BV 2 MICROGLIAL CELL; CELL CULTURE; CELL DEATH; CONTROLLED STUDY; DRUG MECHANISM; FLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; MALE; MICROGLIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; CELL NUCLEUS; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; MAPK SIGNALING; METABOLISM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL LINE; CELL NUCLEUS; IMMUNOHISTOCHEMISTRY; MAP KINASE SIGNALING SYSTEM; METHAMPHETAMINE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, SIGMA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84983775763     PISSN: 18715273     EISSN: 19963181     Source Type: Journal    
DOI: 10.2174/1871527315666160518122816     Document Type: Article

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