Sigma receptor antagonists attenuate acute methamphetamine-induced hyperthermia by a mechanism independent of IL-1β mRNA expression in the hypothalamus

European Journal of Pharmacology

Volumn 691, Issue 1-3, 2012, Pages 103-109

  Seminerio, Michael J ^a   Robson, Matthew J ^a   McCurdy, Christopher R ^b,c   Matsumoto, Rae R ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Hyperthermia; Hypothalamus; Interleukin 1 ; Methamphetamine; Sigma receptor

Indexed keywords

3 [4 (4 CYCLOHEXYLPIPERAZIN 1 YL)PENTYL] 6 FLOUROBENZO[D]THIAZOL 2(3H) ONE; 6 ACETYL 3 [4 [4 (4 FLUOROPHENYL)PIPERAZIN 1 YL]BUTYL]BENZO[D]OXAZOL 2(3H) ONE; AZ 66; INTERLEUKIN 1BETA; MESSENGER RNA; METHAMPHETAMINE; OPIATE ANTAGONIST; SIGMA OPIATE RECEPTOR; SIGMA RECEPTOR ANTAGONIST; SN 79; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; CORE TEMPERATURE; CORPUS STRIATUM; DRUG EFFECT; DRUG MECHANISM; GENE EXPRESSION; HYPERTHERMIA; HYPOTHALAMUS; MALE; MOUSE; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; THERMODYNAMICS; TREATMENT RESPONSE;

ANIMALS; BODY TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEVER; GENE EXPRESSION REGULATION; HYPOTHALAMUS; INTERLEUKIN-1BETA; MALE; METHAMPHETAMINE; MICE; NEUROTOXINS; PIPERAZINES; RECEPTORS, SIGMA; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; TIME FACTORS;

EID: 84864968135     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.07.029     Document Type: Article

References (58)

1. Y. Ago, S. Nakamura, M. Uda, Y. Kajii, M. Abe, A. Baba, and T. Matsuda Attenuation bythe 5-HT1A receptor agonist osemozotan of the behavioral effects of single and repeated methamphetamine in mice Neuropharmacology 51 2006 914 922 (Pubitemid 44376402)
2. M. Aibiki, S. Maekawa, T. Nishiyama, K. Seki, and S. Yokono Activated cytokine production in patients with accidental hypothermia Resuscitation 41 1999 263 268 (Pubitemid 29457630)
3. T.E. Albertson, R.W. Derlet, and B.E. Van Hoozen Methamphetamine and the expanding complications of amphetamines West. J. Med. 170 1999 214 219 (Pubitemid 32612757)
4. C.E. Bandtlow, M. Meyer, D. Lindholm, M. Spranger, R. Heumann, and H. Thoenen Regional and cellular codistribution of interleukin 1 beta and nerve growth factor mRNA in the adult rat brain: possible relationship to the regulation of nerve growth factor synthesis J. Cell Biol. 111 1990 1701 1711
5. N.S. Bhide, J.W. Lipton, J.I. Cunningham, B.K. Yamamoto, and G.A. Gudelsky Repeated exposure to MDMA provides neuroprotection against subsequent MDMA-induced serotonin depletion in brain Brain Res. 1286 2009 32 41
6. 2 receptor subtypes Neuroscience 76 1997 467 477 (Pubitemid 27008477)
7. J.F. Bowyer, D.L. Davies, L. Schmued, H.W. Broening, G.D. Newport, W. Slikker Jr., and R.R. Holson Further studies of the role of hyperthermia in methamphetamine neurotoxicity J. Pharmacol. Exp. Ther. 268 1994 1571 1580 (Pubitemid 24100380)
8. J.B. Buchanan, N.L. Sparkman, and R.W. Johnson Methamphetamine sensitization attenuates the febrile and neuroinflammatory response to a subsequent peripheral immune stimulus Brain Behav. Immun. 24 2010 502 511
9. J.L. Cadet, I.N. Krasnova, S. Jayanthi, and J. Lyles Neurotoxicity of substituted amphetamines: molecular and cellular mechanisms Neurotoxin Res. 11 2007 183 202
10. J.L. Cadet, M.T. McCoy, N.S. Cai, I.N. Krasnova, B. Ladenheim, G. Beauvais, N. Wilson, W. Wood, K.G. Becker, and A.B. Hodges Methamphetamine preconditioning alters midbrain transcriptional responses to methamphetamine-induced injury in the rat striatum PLoS One 4 2009 e7812
11. B. Cannon, and J. Nedergaard Brown adipose tissue: function and physiological significance Physiol. Rev. 84 2004 277 359 (Pubitemid 38054374)
12. J. Cuevas, A. Rodriguez, A. Behensky, and C. Katnik Afobazole modulates microglial function via activation of both sigma-1 and sigma-2 receptors J. Pharmacol. Exp. Ther. 339 2011 161 172
13. C. Davidson, A.J. Gow, T.H. Lee, and E.H. Ellinwood Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment Brain Res. Rev. 36 2001 1 22 (Pubitemid 32763126)
14. M. Fukumura, G.D. Cappon, C. Pu, H.W. Broening, and C.V. Vorhees A single dose model of methamphetamine-induced neurotoxicity in rats: effects on neostriatal monoamines and glial fibrillary acidic protein Brain Res. 806 1998 1 7 (Pubitemid 29009568)
15. G. Gekker, S. Hu, W.S. Sheng, R.B. Rock, J.R. Lokensgard, and P.K. Peterson Cocaine-induced HIV-1 expression in microglia involves sigma-1 receptors and transforming growth factor-beta1 Int. Immunopharmacol. 6 2006 1029 1033
16. J. Goncalves, T. Martins, R. Ferreira, N. Milhazes, F. Borges, C.F. Ribeiro, J.O. Malva, T.R. Macedo, and A.P. Silva Methamphetamine-induced early increase of IL-6 and TNF-alpha mRNA expression in the mouse brain Ann. N. Y. Acad. Sci. 1139 2008 103 111
17. 3H]dopamine from guinea pig striatal slices is modulated by sigma1 receptor agonists Naunyn. Schmiedebergs Arch. Pharmacol. 356 1997 455 461 (Pubitemid 27402084)
18. N.B. Gross, P.C. Duncker, and J.F. Marshall Striatal dopamine D1 and D2 receptors: widespread influences on methamphetamine-induced dopamine and serotonin neurotoxicity Synapse 65 2011 1144 1155
19. A.A. Hall, Y. Herrera, C.T. Ajmo Jr., J. Cuevas, and K.R. Pennypacker Sigma receptors suppress multiple aspects of microglial activation Glia 57 2009 744 754
20. A.K. Halladay, A. Kusnecov, L. Michna, T. Kita, C. Hara, and G.C. Wagner Relationshipbetween methamphetamine-induced dopamine release, hyperthermia, self-injurious behaviour and long term dopamine depletion in BALB/c and C57BL/6 mice Pharmacol. Toxicol. 93 2003 33 41 (Pubitemid 36819372)
21. A.B. Hodges, B. Ladenheim, M.T. McCoy, G. Beauvais, N. Cai, I.N. Krasnova, and J.L. Cadet Long-term protective effects of methamphetamine preconditioning against single-day methamphetamine toxic challenges Curr. Neuropharmacol. 9 2011 35 39
22. N. Kaushal, M. Elliott, M.J. Robson, A.K. Iyer, Y. Rojanasakul, A. Coop, and R.R. Matsumoto AC927, a sigma receptor ligand, blocks methamphetamine- induced release of dopamine and generation of reactive oxygen species in NG108-15 cells Mol. Pharmacol. 81 2012 299 308
23. N. Kaushal, C.R. McCurdy, and R.R. Matsumoto SN79 attenuates the neurotoxic effects of methamphetamine: In vivo and in vitro studies Soc. Neurosci. 2011 (2011 Abstract no. 367.03)
24. N. Kaushal, M.J. Robson, H. Vinnakota, S. Narayanan, B.A. Avery, C.R. McCurdy, and R.R. Matsumoto Synthesis and pharmacological evaluation of 6-acetyl-3-(4-(4-(4-fluorophenyl)piperazin-1-yl)butyl)benzo[d]oxazol-2(3H)-one (SN79), a cocaine antagonist in Rodents AAPS J. 13 2011 336 346
25. N. Kaushal, M.J. Seminerio, J. Shaikh, M.A. Medina, C. Mesangeau, L.L. Wilson, C.R. McCurdy, and R.R. Matsumoto CM156, a high affinity sigma ligand, attenuates the stimulant and neurotoxic effects of methamphetamine in mice Neuropharmacology 61 2011 992 1000
26. M.J. Kluger Fever: role of pyrogens and cryogens Physiol. Rev. 71 1991 93 127
27. R. Kuczenski, D.S. Segal, A.K. Cho, and W. Melega Hippocampus norepinephrine, caudate dopamine and serotonin, and behavioral responses to the stereoisomers of amphetamine and methamphetamine J. Neurosci. 15 1995 1308 1317
28. D.M. Kuhn, D.M. Francescutti-Verbeem, and D.M. Thomas Dopamine quinones activate microglia and induce a neurotoxic gene expression profile: relationship to methamphetamine-induced nerve ending damage Ann. N. Y. Acad. Sci. 1074 2006 31 41 (Pubitemid 44532808)
29. E. Kvaratskhelia, E. Maisuradze, N.G. Dabrundashvili, N. Natsvlishvili, E. Zhuravliova, and D.G. Mikeladze N-methyl-d-aspartate and sigma-ligands change the production of interleukins 8 and 10 in lymphocytes through modulation of the NMDA glutamate receptor Neuroimmunomodulation 16 2009 201 207
30. Y.T. Lai, Y.P. Tsai, C.G. Cherng, J.J. Ke, M.C. Ho, C.W. Tsai, and L. Yu Lipopolysaccharide mitagates methamphetamine-induced striatal dopamine depletion via modulating local TNF-alpha and dopamine transporter expression J. Neural. Transm. 116 2009 405 415
31. L.R. Leon Invited review: cytokine regulation of fever: studies using gene knockout mice J. Appl. Physiol. 92 2002 2648 2655 (Pubitemid 34666396)
32. X. Li, H. Wang, P. Qiu, and H. Luo Proteomic profiling of proteins associated with methamphetamine-induced neurotoxicity in different regions of rat brain Neurochem. Int. 52 2008 256 264 (Pubitemid 350235699)
33. 3H]dopamine release Eur. J. Pharmacol. 422 2001 39 45 (Pubitemid 32595572)
34. D.W. Marion, L.E. Penrod, S.F. Kelsey, W.D. Obrist, P.M. Kochanek, A.M. Palmer, S.R. Wisniewski, and S.T. DeKosky Treatment of traumatic brain injury with moderate hypothermia N. Engl. J. Med. 336 1997 540 546 (Pubitemid 27085734)
35. T. Matsui, Y. Motoki, T. Inomoto, D. Miura, Y. Kato, H. Suenaga, K. Hino, and J. Nojima Temperature-related effects of adenosine triphosphate-activated microglia on pro-inflammatory factors Neurocrit. Care 2011 (Epub ahead of print)
36. R.R. Matsumoto, J. Shaikh, L.L. Wilson, S. Vedam, and A. Coop Attenuation of methamphetamine-induced effects through the antagonism of sigma (σ) receptors: evidence from in vivo and in vitro studies Eur. Neuropsychopharmacol. 18 2008 871 881
37. A. Mayado, E. Torres, M.D. Gutierrez-Lopez, M.I. Colado, and E. O'Shea Increased interleukin-1beta levels following low dose MDMA induces tolerance against the 5-HT neurotoxicity produced by challenge MDMA J. Neuroinflammation 8 2011 165
38. E.C. Nguyen, K.A. McCracken, Y. Liu, B. Pouw, and R.R. Matsumoto Involvement of sigma (σ) receptors in the acute actions of methamphetamine: receptor binding and behavioral studies Neuropharmacology 49 2005 638 645 (Pubitemid 41208285)
39. Y. Numachi, A. Ohara, M. Yamashita, S. Fukushima, H. Kobayashi, H. Hata, H. Watanabe, F.S. Hall, K.P. Lesch, D.L. Murphy, G.R. Uhl, and I. Sora Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters Eur. J. Pharmacol. 572 2007 120 128 (Pubitemid 47429639)
40. 3H]dopamine release is dependent upon protein kinase C J. Pharmacol. Exp. Ther. 304 2003 364 369 (Pubitemid 36008950)
41. L. Orio, E. O'Shea, V. Sanchez, J.M. Pradillo, I. Escobedo, J. Camarero, M.A. Moro, A.R. Green, and M.I. Colado 3,4-Methylenedioxymethamphetamine increases interleukin-1β levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5-HT depletion J. Neurochem. 89 2004 1445 1453 (Pubitemid 38802666)
42. G. Phelps, H.A. Speaker, and K.E. Sabol Relationship between methamphetamine-induced behavioral activation and hyperthermia Brain Res. 1357 2010 41 52
43. K.R. Rodvelt, and D.K. Miller Could sigma receptor ligands be a treatment for methamphetamine addiction? Curr. Drug Abuse Rev. 3 2010 156 162
44. D.E. Rusyniak, Y. Ootsuka, and W.W. Blessing When administered to rats in a cold environment, 3,4-methylenedioxymethamphetamine reduces brown adipose tissue thermogenesis and increases tail blood flow: effects of pretreatment with 5-HT1A and dopamine D2 antagonists Neuroscience 154 2008 1619 1626
45. P. Salmi, and S. Ahlenius Evidence for functional interactions between 5-HT1A and 5-HT2A receptors in rat thermoregulatory mechanisms Pharmacol. Toxicol. 82 1998 122 127 (Pubitemid 28131367)
46. P. Salmi, P. Jimenez, and S. Ahlenius Evidence for specific involvement of dopamine D1 and D2 receptors in the regulation of body temperature in the rat Eur. J. Pharmacol. 236 1993 395 400 (Pubitemid 23170380)
47. P.J. Schwartz, T.A. Wehr, N.E. Rosenthal, J.J. Bartko, D.A. Oren, C. Luetke, and D.L. Murphy Serotonin and thermoregulation. Physiologic and pharmacologic aspects of control revealed by intravenous m-CPP in normal human subjects Neuropsychopharmacology 13 1995 105 115
48. Y. Sekine, Y. Ouchi, G. Sugihara, N. Takei, E. Yoshikawa, K. Nakamura, Y. Iwata, K.J. Tsuchiya, S. Suda, K. Suzuki, M. Kawai, K. Takebayashi, S. Yamamoto, H. Matsuzaki, T. Ueki, N. Mori, M.S. Gold, and J.L. Cadet Methamphetamine causes microglial activation in the brains of human abusers J. Neurosci. 28 2008 5756 5761
49. M.J. Seminerio, N. Kaushal, J. Shaikh, J.D. Huber, A. Coop, and R.R. Matsumoto Sigma (σ) receptor ligand, AC927 (N-phenethylpiperidine oxalate), attenuates methamphetamine-induced hyperthermia and serotonin damage in mice Pharmacol. Biochem. Behav. 98 2011 12 20
50. M.J. Seminerio, M.J. Robson, A.H. Abdelazeem, C. Mesangeau, S. Jamalapuram, B.A. Avery, C.R. McCurdy, and R.R. Matsumoto Synthesis and pharmacological characterization of a novel sigma receptor ligand with improved metabolic stability andantagonistic effects against methamphetamine AAPS J. 14 2012 43 51
51. J.E. Sprague, N.M. Mallett, D.E. Rusyniak, and E. Mills UCP3 and thyroid hormone involvement in methamphetamine-induced hyperthermia Biochem. Pharmacol. 68 2004 1339 1343 (Pubitemid 39179392)
52. 1 receptor ligand, reverses phencyclidine-induced release of dopamine and serotonin in rat brain Eur. J. Pharmacol. 427 2001 211 219 (Pubitemid 32913288)
53. United Nations, 2007. United Nations Office on Drugs and Crime World Drug Report Analysis. Volume 1, Vienna.
54. G. Wang, J. Zhang, W. Li, G. Xin, Y. Su, Y. Gao, H. Zhang, G. Lin, X. Jiao, and K. Li Apoptosis and proinflammatory cytokine responses of primary mouse microglia and astrocytes induced by human H1N1 and avian H5N1 influenza viruses Cell Mol. Immunol. 5 2008 113 120
55. P. Wang, N.J. Rothwell, E. Pinteaux, and D. Brough Neuronal injury induces the release of pro-interleukin-1β from activated microglia in vitro Brain Res. 1236 2008 1 7
56. Y.T. Xu, M.J. Robson, W. Szeszel-Fedorowicz, D. Patel, R. Rooney, C.R. McCurdy, and R.R. Matsumoto CM156, a sigma receptor ligand, reverses cocaine-induced place conditioning and transcriptional responses in the brain Pharmacol. Biochem. Behav. 101 2012 174 180
57. T. Yamaguchi, Y. Kuraishi, M. Minami, S. Nakai, Y. Hirai, and M. Satoh Methamphetamine-induced expression of interleukin-1 beta mRNA in the rat hypothalamus Neurosci. Lett. 128 1991 90 92
58. H. Yao, Y. Yang, K.J. Kim, C. Bethel-Brown, N. Gong, K. Funa, H.E. Gendelman, T.P. Su, J.Q. Wang, and S. Buch Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration Blood 115 2010 4951 4962