Structures of torsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia

eLife

Volumn 5, Issue AUGUST, 2016, Pages

  Esra Demircioglu, F ^a   Sosa, Brian A ^a   Ingram, Jessica ^b   Ploegh, Hidde L ^b   Schwartz, Thomas U ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LUMINAL DOMAIN LIKE LAP1; PEPTIDES AND PROTEINS; TYROSINE A; UNCLASSIFIED DRUG; CARRIER PROTEIN; CHAPERONE; MEMBRANE PROTEIN; PROTEIN BINDING; TOR1A PROTEIN, HUMAN; TOR1AIP2 PROTEIN, HUMAN;

ARTICLE; BIOINFORMATICS; DYSTONIA; MUTATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; X RAY CRYSTALLOGRAPHY; CHEMISTRY; DYSTONIC DISORDER; GENETICS; HUMAN; METABOLISM; MOLECULAR MODEL; PATHOPHYSIOLOGY; PROTEIN CONFORMATION;

CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; DYSTONIC DISORDERS; HUMANS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MOLECULAR CHAPERONES; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84983681814     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.17983     Document Type: Article

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