Hypoxia Responsive, Tumor Penetrating Lipid Nanoparticles for Delivery of Chemotherapeutics to Pancreatic Cancer Cell Spheroids

Bioconjugate Chemistry

Volumn 27, Issue 8, 2016, Pages 1830-1838

  Kulkarni, Prajakta ^a   Haldar, Manas K ^a   Katti, Preeya ^b,c   Dawes, Courtney ^d   You, Seungyong ^a   Choi, Yongki ^a   Mallik, Sanku ^a  

^a NORTH DAKOTA STATE UNIVERSITY   (United States)

^b Davies High School   (United States)

^c Valley City High School   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD VESSELS; CONTROLLED DRUG DELIVERY; CYTOLOGY; DISEASES; HISTOLOGY; MICROCIRCULATION; OXYGEN; PARTIAL PRESSURE; PEPTIDES; STEM CELLS; SYNTHESIS (CHEMICAL); TARGETED DRUG DELIVERY; TUMORS;

BLOOD FLOW; CANCER CELLS; CELL SPHEROIDS; GENETIC MAKE-UP; LIPID NANOPARTICLES; PANCREATIC CANCERS; PARTIAL PRESSURE OF OXYGEN; SOLID TUMORS; TUMOR PROGRESSIONS; TUMOUR TISSUE;

NANOPARTICLES;

AZOBENZENE; GEMCITABINE; HYPOXIA RESPONSIVE LIPID NANOPARTICLE; IRGD PEPTIDE; MACROGOL; NANOPARTICLE; PEPTIDE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ARGINYL-GLYCYL-ASPARTIC ACID; AZO COMPOUND; DRUG CARRIER; MACROGOL DERIVATIVE; OLIGOPEPTIDE; PHOSPHOLIPID;

ANIMAL CELL; ARTICLE; ATOMIC FORCE MICROSCOPY; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ENCAPSULATION; HYPOXIA; LIPID MEMBRANE; NONHUMAN; PANCREATIC CANCER CELL LINE; PARTIAL PRESSURE; RAT; SPHEROID CELL; CELL SURVIVAL; CHEMISTRY; CONFORMATION; DRUG EFFECTS; DRUG RELEASE; HUMAN; METABOLISM; MOLECULAR MODEL; MULTICELLULAR SPHEROID; PANCREAS TUMOR; PATHOLOGY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; TUMOR HYPOXIA;

ANTINEOPLASTIC AGENTS; AZO COMPOUNDS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL SURVIVAL; DRUG CARRIERS; DRUG LIBERATION; HUMANS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NANOPARTICLES; OLIGOPEPTIDES; PANCREATIC NEOPLASMS; PHOSPHOLIPIDS; POLYETHYLENE GLYCOLS; SPHEROIDS, CELLULAR; TUMOR HYPOXIA;

EID: 84983628201     PISSN: 10431802     EISSN: 15204812     Source Type: Journal    
DOI: 10.1021/acs.bioconjchem.6b00241     Document Type: Article

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