Synergistic Action of Staphylococcus aureus α-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis

Cell Host and Microbe

Volumn 17, Issue 6, 2015, Pages 775-787

  Powers, Michael E ^a   Becker, Russell E N ^a   Sailer, Anne ^a   Turner, Jerrold R ^a   Bubeck Wardenburg, Juliane ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM10 ENDOPEPTIDASE; ALANINE AMINOTRANSFERASE; ALPHA TOXIN; CASPASE 2; CASPASE 3; CASPASE 4; CD11B ANTIGEN; COLLAGEN RELATED PEPTIDE; GLYCOPROTEIN; HISTAMINE; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MYELOPEROXIDASE; PADGEM PROTEIN; PEPTIDE; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; ADAM PROTEIN; ADAM10 PROTEIN, MOUSE; BACTERIAL TOXIN; HEMOLYSIN; MEMBRANE PROTEIN; SECRETASE; STAPHYLOCOCCAL ALPHA-TOXIN;

ACUTE LUNG INJURY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOODSTREAM INFECTION; BONE MARROW CELL; CELL AGGREGATION; CELL LINEAGE; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; ENZYME ACTIVITY; EXTRACELLULAR TRAP; FLOW CYTOMETRY; GENE INACTIVATION; GENETIC POLYMORPHISM; HLA SYSTEM; HUMAN; HUMAN CELL; INNATE IMMUNITY; LETHAL SEPSIS; LIVER INJURY; LUNG HEMORRHAGE; MORTALITY; MOUSE; MULTI ORGAN INJURY; NEUTROPHIL; NEUTROPHIL AGGREGATION; NONHUMAN; ORGAN INJURY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; SEPSIS; STAPHYLOCOCCUS AUREUS; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; WILD TYPE; ANIMAL; BACTEREMIA; DRUG EFFECTS; GENETICS; HOST PATHOGEN INTERACTION; KNOCKOUT MOUSE; LIVER; METABOLISM; MICROBIOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; TRANSGENIC MOUSE;

ACUTE LUNG INJURY; ADAM PROTEINS; ADAM10 PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BACTEREMIA; BACTERIAL TOXINS; BLOOD PLATELETS; CELL LINEAGE; HEMOLYSIN PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERLEUKIN-1BETA; LIVER; MEMBRANE PROTEINS; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUTROPHILS; PLATELET AGGREGATION;

EID: 84983488777     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2015.05.011     Document Type: Article

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