Targeting Staphylococcus aureus α-toxin as a novel approach to reduce severity of recurrent skin and soft-tissue infections

Journal of Infectious Diseases

Volumn 210, Issue 7, 2014, Pages 1012-1018

  Sampedro, Georgia R ^a   De Dent, Andrea C ^a   Becker, Russell E N ^a   Berube, Bryan J ^a   Gebhardt, Michael J ^a   Cao, Hongyuan ^a   Wardenburg, Juliane Bubeck ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Novel therapeutics; Recurrent infection; Skin and soft tissue infection; Staphylococcus aureus; toxin

Indexed keywords

ADAM10 ENDOPEPTIDASE; ADAM10 ENDOPEPTIDASE INHIBITOR; ENZYME INHIBITOR; GI 254023X; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY HLA; STAPHYLOCOCCUS ALPHA TOXIN; UNCLASSIFIED DRUG; BACTERIAL TOXIN; HEMOLYSIN; STAPHYLOCOCCAL ALPHA-TOXIN;

ABSCESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG TARGETING; INFECTION; MALE; MOUSE; NONHUMAN; PRIMARY INFECTION; PRIORITY JOURNAL; RECURRENT INFECTION; REINFECTION; SKIN AND SOFT TISSUE INFECTION; STAPHYLOCOCCAL SKIN INFECTION; STAPHYLOCOCCUS AUREUS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; METABOLISM; PATHOLOGY; PHYSIOLOGY; RECURRENT DISEASE; SOFT TISSUE INFECTIONS; STAPHYLOCOCCAL SKIN INFECTIONS;

ANIMALS; BACTERIAL TOXINS; HEMOLYSIN PROTEINS; MALE; MICE, INBRED C57BL; RECURRENCE; SOFT TISSUE INFECTIONS; STAPHYLOCOCCAL SKIN INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 84922394624     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu223     Document Type: Article

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