Female mice lacking Xist RNA show partial dosage compensation and survive to term

Genes and Development

Volumn 30, Issue 15, 2016, Pages 1747-1760

  Yang, Lin ^a,b   Kirby, James E ^b   Sunwoo, Hongja ^a,b   Lee, Jeannie T ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Dosage compensation; Genome balance; Inverse effect; Knockout mouse; Transcriptomics; X inactivation; Xist

Indexed keywords

RNA; LONG UNTRANSLATED RNA; XIST NON-CODING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOSOME; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; MOUSE; MUTANT MOUSE STRAIN; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; SURVIVAL; TRANSCRIPTOMICS; X CHROMOSOME; X CHROMOSOME INACTIVATION; XIST GENE; ANIMAL; CARDIAC MUSCLE; GENE DELETION; GENETICS; MALE; PATHOLOGY; SPLEEN; SURVIVAL ANALYSIS;

ANIMALS; DOSAGE COMPENSATION, GENETIC; EMBRYONIC DEVELOPMENT; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; MYOCARDIUM; RNA, LONG NONCODING; SEQUENCE DELETION; SPLEEN; SURVIVAL ANALYSIS; X CHROMOSOME; X CHROMOSOME INACTIVATION;

EID: 84983315107     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.281162.116     Document Type: Article

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