p75NTR and its ligand ProNGF activate paracrine mechanisms etiological to the vascular, inflammatory, and neurodegenerative pathologies of diabetic retinopathy

Journal of Neuroscience

Volumn 36, Issue 34, 2016, Pages 8826-8841

  Barcelona, Pablo F ^a,b   Sitaras, Nicholas ^c   Galan, Alba ^a   Esquiva, Gema ^d   Jmaeff, Sean ^a,b   Jian, Yifan ^e   Sarunic, Marinko V ^e   Cuenca, Nicolas ^d   Sapieha, Przemyslaw ^b,c   Saragovi, H Uri ^a,b,f  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF MONTREAL   (Canada)

^d UNIVERSITY OF ALICANTE   (Spain)

^e SIMON FRASER UNIVERSITY   (Canada)

^f MCGILL UNIVERSITY   (Canada)

Author keywords

Diabetes; Neurodegeneration; Neurotrophin; Pathophysiology; Receptor; Retina

Indexed keywords

ALPHA 2 MACROGLOBULIN; NERVE GROWTH FACTOR RECEPTOR; NEUROTROPHIN RECEPTOR P75; SEMAPHORIN 3A; TUMOR NECROSIS FACTOR; ANTIBODY; CONDITIONED MEDIUM; CYTOKINE; NERVE GROWTH FACTOR; PRO-NERVE GROWTH FACTOR, MOUSE; PROTEIN PRECURSOR; STREPTOZOCIN; TNFRSF16 PROTEIN, MOUSE;

ADULT; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B SCAN; BLOOD RETINA BARRIER; BLOOD VESSEL PERMEABILITY; CELL COUNT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETIC RETINOPATHY; DISEASE COURSE; EDEMA; EXPERIMENTAL DIABETES MELLITUS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; ISCHEMIA; MALE; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NEWBORN; NONHUMAN; OPTICAL COHERENCE TOMOGRAPHY; OXYGEN-INDUCED RETINOPATHY; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; RETINA GANGLION CELL; RETINAL THICKNESS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ASTROCYTE; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; CHEMISTRY; COMPLICATION; CONDITIONED MEDIUM; DISEASE MODEL; DRUG EFFECTS; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; METABOLISM; NEURODEGENERATIVE DISEASES; PATHOLOGY; PHARMACOLOGY; PHYSIOLOGY; RAT; RETINA; VASCULAR DISEASES; VISUAL SYSTEM;

ANIMALS; ANIMALS, NEWBORN; ANTIBODIES; ASTROCYTES; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; CYTOKINES; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IN SITU NICK-END LABELING; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; NERVE GROWTH FACTOR; NEURODEGENERATIVE DISEASES; PROTEIN PRECURSORS; RATS; RECEPTORS, NERVE GROWTH FACTOR; RETINA; STREPTOZOCIN; TOMOGRAPHY, OPTICAL COHERENCE; VASCULAR DISEASES; VISUAL PATHWAYS;

EID: 84983273975     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4278-15.2016     Document Type: Article

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