Metformin affects the features of a human hepatocellular cell line (HepG2) by regulating macrophage polarization in a co-culture microenviroment

Diabetes/Metabolism Research and Reviews

Volumn 31, Issue 8, 2015, Pages 781-789

  Chen, Miaojiao ^a,b,c   Zhang, Jingjing ^a   Hu, Fang ^a   Liu, Shiping ^a,b,c   Zhou, Zhiguang ^a,b,c  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c National Clinical Research Center for Metabolic Diseases   (China)

Author keywords

Hepatoma; Inflammation; Macrophage; Metformin; Notch; Polarization

Indexed keywords

MESSENGER RNA; METFORMIN; MONOCYTE CHEMOTACTIC PROTEIN 1; NOTCH RECEPTOR; ANTIDIABETIC AGENT; CCL2 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; COCULTURE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; MACROPHAGE; MICROENVIRONMENT; MOUSE; NONHUMAN; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL DIFFERENTIATION; CELL POLARITY; CYTOLOGY; DRUG EFFECTS; HEP-G2 CELL LINE; METABOLISM;

APOPTOSIS; CELL DIFFERENTIATION; CELL POLARITY; CHEMOKINE CCL2; COCULTURE TECHNIQUES; HEP G2 CELLS; HUMANS; HYPOGLYCEMIC AGENTS; MACROPHAGES; METFORMIN; SIGNAL TRANSDUCTION;

EID: 84983135302     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.2761     Document Type: Article

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