Functional analysis of AEBP2, a PRC2 polycomb protein, reveals a trithorax phenotype in embryonic development and in ESCs

Development (Cambridge)

Volumn 143, Issue 15, 2016, Pages 2716-2723

  Grijzenhout, Anne ^a   Godwin, Jonathan ^a   Koseki, Haruhiko ^b   Gdula, Michal Ryszard ^a   Szumska, Dorota ^c   McGouran, Joanna F ^d,e   Bhattacharya, Shoumo ^c   Kessler, Benedikt M ^d   Brockdorff, Neil ^a   Cooper, Sarah ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b Institute of Physical and Chemical Research   (Japan)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

AEBP2; Chromatin; Mouse; Polycomb; PRC2; Trithorax

Indexed keywords

AEBP2 PROTEIN; HISTONE H3; HOX PROTEIN; LEUKEMIA INHIBITORY FACTOR; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; UNCLASSIFIED DRUG; AEBP2 PROTEIN, MOUSE; DNA BINDING PROTEIN; HISTONE; NUCLEAR PROTEIN;

ALLELE; ANIMAL CELL; ARTICLE; BIOCHEMICAL ANALYSIS; CHROMATIN IMMUNOPRECIPITATION; CPG ISLAND; ELECTRON MICROSCOPY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYOID BODY; EMBRYONIC STEM CELL; EXON; FEMALE; GEL FILTRATION; GENE MUTATION; GENETIC BACKGROUND; HETEROZYGOTE; HISTONE METHYLATION; HOMOZYGOTE; HYPOPIGMENTATION; IMMUNOFLUORESCENCE; LIQUID CHROMATOGRAPHY; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN QUATERNARY STRUCTURE; PROTEOMICS; TANDEM MASS SPECTROMETRY; TROPHOBLAST; WILD TYPE; X CHROMOSOME; ANIMAL; CELL LINE; CYTOLOGY; GENETICS; METABOLISM; MUTATION; PROCEDURES;

ANIMALS; CELL LINE; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; FEMALE; HISTONES; MICE; MUTATION; NUCLEAR PROTEINS; POLYCOMB REPRESSIVE COMPLEX 2; PROTEOMICS;

EID: 84982994322     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.123935     Document Type: Article

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