Breast cancer cells compete with hematopoietic stem and progenitor cells for intercellular adhesion molecule 1-mediated binding to the bone marrow microenvironment

Carcinogenesis

Volumn 37, Issue 8, 2016, Pages 759-767

  Dhawan, Abhishek ^a   Friedrichs, Jens ^b   Von Bonin, Malte ^a,c,d   Bejestani, Elham Peshali ^c,d   Werner, Carsten ^b   Wobus, Manja ^a   Chavakis, Triantafyllos ^e   Bornhäuser, Martin ^a,c  

^a UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^b LEIBNIZ INSTITUTE OF POLYMER RESEARCH DRESDEN   (Germany)

^c German Consortium for Translational Cancer Research   (Germany)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^e DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD18 ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; ICAM1 PROTEIN, HUMAN; PROTEIN BINDING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOMIC FORCE MICROSCOPY; BONE MARROW; BREAST CANCER; BREAST METASTASIS; CANCER CELL; CELL ADHESION; CELL INTERACTION; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TUMOR CELL; XENOTRANSPLANTATION; ANIMAL; BINDING SITE; BONE MARROW CELL; BREAST TUMOR; DRUG SCREENING; FEMALE; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; METASTASIS; PATHOLOGY; TUMOR MICROENVIRONMENT;

ANIMALS; ANTIGENS, CD18; BINDING SITES; BONE MARROW CELLS; BREAST NEOPLASMS; FEMALE; HEMATOPOIETIC STEM CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MESENCHYMAL STROMAL CELLS; MICE; NEOPLASM METASTASIS; PROTEIN BINDING; TUMOR MICROENVIRONMENT; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84982983885     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgw057     Document Type: Article

References (45)

1. Chambers, A.F. et al. (2002) Dissemination and growth of cancer cells in metastatic sites. Nat. Rev. Cancer, 2, 563-572.
2. Valastyan, S. et al. (2011) Tumor metastasis: molecular insights and evolving paradigms. Cell, 147, 275-292.
3. Wan, L. et al. (2013) Tumor metastasis: moving new biological insights into the clinic. Nat. Med., 19, 1450-1464.
4. Kamińska, K. et al. (2015) The role of the cell-cell interactions in cancer progression. J. Cell. Mol. Med., 19, 283-296.
5. Jin, J.K. et al. (2011) Steps in prostate cancer progression that lead to bone metastasis. Int. J. Cancer, 128, 2545-2561.
6. Malanchi, I. et al. (2012) Interactions between cancer stem cells and their niche govern metastatic colonization. Nature, 481, 85-89.
7. Bailey, J.M. et al. (2007) Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins. J. Cell. Biochem., 102, 829-839.
8. Lu, P. et al. (2012) The extracellular matrix: a dynamic niche in cancer progression. J. Cell Biol., 196, 395-406.
9. Egeblad, M. et al. (2002) New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer, 2, 161-174.
10. Deryugina, E.I. et al. (2006) Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev., 25, 9-34.
11. Lu, X. et al. (2009) ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. Genes Dev., 23, 1882-1894.
12. Boyerinas, B. et al. (2013) Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy. Blood, 121, 4821-4831.
13. Jin, L. et al. (2006) Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat. Med., 12, 1167-1174.
14. Spaeth, E.L. et al. (2013) Mesenchymal CD44 expression contributes to the acquisition of an activated fibroblast phenotype via TWIST activation in the tumor microenvironment. Cancer Res., 73, 5347-5359.
15. Fujisaki, T. et al. (1999) CD44 stimulation induces integrin-mediated adhesion of colon cancer cell lines to endothelial cells by up-regulation of integrins and c-Met and activation of integrins. Cancer Res., 59, 4427-4434.
16. Mundy, G.R. (1997) Mechanisms of bone metastasis. Cancer 80,1546-1556.
17. Roodman, G.D. (2004) Mechanisms of bone metastasis. N. Engl. J. Med., 350, 1655-1664.
18. Shiozawa, Y. et al. (2011) Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow. J. Clin. Invest., 121, 1298-1312.
19. Jung, Y. et al. (2007) Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation. Blood, 110, 82-90.
20. Wobus, M. et al. (2015) Breast carcinoma cells modulate the chemoat-tractive activity of human bone marrow-derived mesenchymal stromal cells by interfering with CXCL12. Int. J. Cancer, 136, 44-54.
21. Friedrichs J, Helenius J, Muller DJ (2010) Quantifying cellular adhesion to extracellular matrix components by single-cell force spectroscopy. Nat. Protoc., 5, 1353-1361.
22. Hutter, J.L. et al. (1993) Calibration of atomic-force microscope tips. Rev. Sci. Instrum., 64,1868-1873.
23. Waskow, C. et al. (2008) The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues. Nat. Immunol., 9, 676-683.
24. O'Hanlon, D.M. et al. (2002) Soluble adhesion molecules (E-selectin, ICAM-1 and VCAM-1) in breast carcinoma. Eur. J. Cancer, 38, 2252-2257.
25. Schröder, C. et al. (2011) Prognostic value of intercellular adhesion molecule (ICAM)-1 expression in breast cancer. J. Cancer Res. Clin. Oncol., 137, 1193-1201.
26. Bella, J. et al. (1999) The structure of the two amino-terminal domains of human intercellular adhesion molecule-1 suggests how it functions as a rhinovirus receptor. Virus Res., 62, 107-117.
27. Frick, C. et al. (2005) Interaction of ICAM-1 with beta 2-integrin CD11c/ CD18: characterization of a peptide ligand that mimics a putative binding site on domain D4 of ICAM-1. Eur. J. Immunol., 35, 3610-3621.
28. Rosenstein, Y. et al. (1991) CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1. Nature, 354, 233-235.
29. Duperray, A. et al. (1997) Molecular identification of a novel fibrinogen binding site on the first domain of ICAM-1 regulating leukocyteendothelium bridging. J. Biol. Chem., 272, 435-441.
30. Momosaki, S. et al. (1995) Expression of intercellular adhesion molecule 1 in human hepatocellular carcinoma. Hepatology, 22, 1708-1713.
31. Yu, J.A. et al. (2012) Lung cancer cell invasion and expression of inter-cellular adhesion molecule-1 (ICAM-1) are attenuated by secretory phospholipase A inhibition. J. Thorac. Cardiovasc. Surg., 143, 405-411.
32. Rosette, C. et al. (2005) Role of ICAM1 in invasion of human breast cancer cells. Carcinogenesis, 26, 943-950.
33. Ell, B. et al. (2013) Tumor-induced osteoclast miRNA changes as regulators and biomarkers of osteolytic bone metastasis. Cancer Cell, 24, 542-556.
34. Suresh, S. (2007) Biomechanics and biophysics of cancer cells. Acta Bio-mater., 3, 413-438.
35. Choi, J.S. et al. (2012) The combined influence of substrate elasticity and ligand density on the viability and biophysical properties of hematopoietic stem and progenitor cells. Biomaterials, 33, 4460-4468.
36. Conway, A. et al. (2012) Biophysical regulation of stem cell behavior within the niche. Stem Cell Res. Ther., 3, 50.
37. Corbin, E.A. et al. (2015) Biophysical properties of human breast cancer cells measured using silicon MEMS resonators and atomic force microscopy. Lab Chip, 15, 839-847.
38. Hayflick, J.S. et al. (1998) The intercellular adhesion molecule (ICAM) family of proteins. New members and novel functions. Immunol. Res., 17, 313-327.
39. Hubbard, A.K. et al. (2000) Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades. Free Radic. Biol. Med., 28, 1379-1386.
40. Kammerer, S. et al. (2005) Association of the NuMA region on chromo-some 11q13 with breast cancer susceptibility. Proc. Natl Acad. Sci. USA, 102, 2004-2009.
41. Reilly, P.L. et al. (1995) The native structure of intercellular adhesion molecule-1 (ICAM-1) is a dimer. Correlation with binding to LFA-1. J. Immunol., 155, 529-532.
42. Miller, J. et al. (1995) Intercellular adhesion molecule-1 dimerization and its consequences for adhesion mediated by lymphocyte function associated-1. J. Exp. Med., 182, 1231-1241.
43. Jun, C.D. et al. (2001) Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion. Proc. Natl Acad. Sci. USA, 98, 6830-6835.
44. Yang, Y. et al. (2004) Structural basis for dimerization of ICAM-1 on the cell surface. Mol. Cell, 14, 269-276.
45. Zeng, G.F. et al. (2011) Up-regulation of METCAM/MUC18 promotes motility, invasion, and tumorigenesis of human breast cancer cells. BMC Cancer, 11, 113.