The combined influence of substrate elasticity and ligand density on the viability and biophysical properties of hematopoietic stem and progenitor cells

Biomaterials

Volumn 33, Issue 18, 2012, Pages 4460-4468

  Choi, Ji S ^a   Harley, Brendan A C ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Cytoskeleton; Fate; Hematopoietic stem cell; Ligand density; Substrate stiffness

Indexed keywords

ADIPOSE TISSUE; ADULT STEM CELLS; BIOPHYSICAL ENVIRONMENTS; BIOPHYSICAL PARAMETERS; BIOPHYSICAL PROPERTIES; BONE MARROW; CRITICAL DESIGN; CYTOSKELETONS; EXTRACELLULAR MATRICES; EXTRINSIC SIGNALS; FATE; GLASS SUBSTRATES; HEMATOPOIETIC STEM CELLS; HOMOLOGOUS SERIES; IMMUNE CELLS; LIGAND CONCENTRATION; LIGAND DENSITY; MICROENVIRONMENTS; MOLECULAR SIGNALS; PROGENITOR CELL; SINGLE-CELL LEVEL; STEM-CELL NICHES;

CELL CULTURE; CELL DEATH; CELL MEMBRANES; ELASTICITY; LIGANDS; PHYSIOLOGICAL MODELS; STIFFNESS; SUBSTRATES; THREE DIMENSIONAL; TISSUE;

STEM CELLS;

COLLAGEN; LIGAND;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; BONE MARROW; CELL CULTURE; CELL FATE; CELL MEMBRANE; CONTROLLED STUDY; DENSITY; ELASTICITY; HEMATOPOIETIC STEM CELL; HYDROGEL; MICROENVIRONMENT; MOUSE; NONHUMAN; OSTEOID; PRIORITY JOURNAL; RIGIDITY;

ACRYLIC RESINS; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; COLLAGEN; CYTOSKELETON; HEMATOPOIETIC STEM CELLS; HYDROGEL; MICE; MICROSCOPY, ATOMIC FORCE; STEM CELL NICHE; STEM CELLS;

EID: 84862824413     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.03.010     Document Type: Article

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