-
1
-
-
0030006070
-
Clonal selection and learning in the antibody system
-
Rajewsky K (1996) Clonal selection and learning in the antibody system. Nature 381(6585):751-758.
-
(1996)
Nature
, vol.381
, Issue.6585
, pp. 751-758
-
-
Rajewsky, K.1
-
3
-
-
84923813876
-
Dynamics of B cells in germinal centres
-
De Silva NS, Klein U (2015) Dynamics of B cells in germinal centres. Nat Rev Immunol 15(3):137-148.
-
(2015)
Nat Rev Immunol
, vol.15
, Issue.3
, pp. 137-148
-
-
De Silva, N.S.1
Klein, U.2
-
4
-
-
34548036949
-
Germinal-center organization and cellular dynamics
-
Allen CD, Okada T, Cyster JG (2007) Germinal-center organization and cellular dynamics. Immunity 27(2):190-202.
-
(2007)
Immunity
, vol.27
, Issue.2
, pp. 190-202
-
-
Allen, C.D.1
Okada, T.2
Cyster, J.G.3
-
5
-
-
84859717525
-
Germinal center selection and the development of memory B and plasma cells
-
Shlomchik MJ, Weisel F (2012) Germinal center selection and the development of memory B and plasma cells. Immunol Rev 247(1):52-63.
-
(2012)
Immunol Rev
, vol.247
, Issue.1
, pp. 52-63
-
-
Shlomchik, M.J.1
Weisel, F.2
-
6
-
-
16844381831
-
Mechanisms of B-cell lymphoma pathogenesis
-
Küppers R (2005) Mechanisms of B-cell lymphoma pathogenesis. Nat Rev Cancer 5(4): 251-262.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.4
, pp. 251-262
-
-
Küppers, R.1
-
7
-
-
84923699047
-
Germinal centres and B cell lymphomagenesis
-
Basso K, Dalla-Favera R (2015) Germinal centres and B cell lymphomagenesis. Nat Rev Immunol 15(3):172-184.
-
(2015)
Nat Rev Immunol
, vol.15
, Issue.3
, pp. 172-184
-
-
Basso, K.1
Dalla-Favera, R.2
-
9
-
-
84925244524
-
The genetic landscape of diffuse large B-cell lymphoma
-
Pasqualucci L, Dalla-Favera R (2015) The genetic landscape of diffuse large B-cell lymphoma. Semin Hematol 52(2):67-76.
-
(2015)
Semin Hematol
, vol.52
, Issue.2
, pp. 67-76
-
-
Pasqualucci, L.1
Dalla-Favera, R.2
-
10
-
-
34547562418
-
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
-
Annunziata CM, et al. (2007) Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell 12(2):115-130.
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 115-130
-
-
Annunziata, C.M.1
-
11
-
-
34547660308
-
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma
-
Keats JJ, et al. (2007) Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. Cancer Cell 12(2):131-144.
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 131-144
-
-
Keats, J.J.1
-
12
-
-
77951719556
-
Classical and/or alternative NF-kappaB pathway activation in multiple myeloma
-
Demchenko YN, et al. (2010) Classical and/or alternative NF-kappaB pathway activation in multiple myeloma. Blood 115(17):3541-3552.
-
(2010)
Blood
, vol.115
, Issue.17
, pp. 3541-3552
-
-
Demchenko, Y.N.1
-
13
-
-
80052269038
-
Analysis of the coding genome of diffuse large B-cell lymphoma
-
Pasqualucci L, et al. (2011) Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet 43(9):830-837.
-
(2011)
Nat Genet
, vol.43
, Issue.9
, pp. 830-837
-
-
Pasqualucci, L.1
-
14
-
-
84922375207
-
Genetic inactivation of TRAF3 in canine and human B-cell lymphoma
-
Bushell KR, et al. (2015) Genetic inactivation of TRAF3 in canine and human B-cell lymphoma. Blood 125(6):999-1005.
-
(2015)
Blood
, vol.125
, Issue.6
, pp. 999-1005
-
-
Bushell, K.R.1
-
15
-
-
84933678552
-
An oncogenic role for alternative NF-kB signaling in DLBCL revealed upon deregulated BCL6 expression
-
Zhang B, et al. (2015) An oncogenic role for alternative NF-kB signaling in DLBCL revealed upon deregulated BCL6 expression. Cell Reports 11(5):715-726.
-
(2015)
Cell Reports
, vol.11
, Issue.5
, pp. 715-726
-
-
Zhang, B.1
-
16
-
-
84942788820
-
Unexpected functions of nuclear factor-?B during germinal center B-cell development: Implications for lymphomagenesis
-
Klein U, Heise N (2015) Unexpected functions of nuclear factor-?B during germinal center B-cell development: Implications for lymphomagenesis. Curr Opin Hematol 22(4):379-387.
-
(2015)
Curr Opin Hematol
, vol.22
, Issue.4
, pp. 379-387
-
-
Klein, U.1
Heise, N.2
-
17
-
-
84858712873
-
NF-kB function in B lymphocytes
-
Kaileh M, Sen R (2012) NF-kB function in B lymphocytes. Immunol Rev 246(1):254-271.
-
(2012)
Immunol Rev
, vol.246
, Issue.1
, pp. 254-271
-
-
Kaileh, M.1
Sen, R.2
-
18
-
-
77955288093
-
Roles of the NF-kappaB pathway in lymphocyte development and function
-
Gerondakis S, Siebenlist U (2010) Roles of the NF-kappaB pathway in lymphocyte development and function. Cold Spring Harb Perspect Biol 2(5):a000182.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.5
, pp. a000182
-
-
Gerondakis, S.1
Siebenlist, U.2
-
19
-
-
10244261528
-
Tracking CD40 signaling during germinal center development
-
Basso K, et al. (2004) Tracking CD40 signaling during germinal center development. Blood 104(13):4088-4096.
-
(2004)
Blood
, vol.104
, Issue.13
, pp. 4088-4096
-
-
Basso, K.1
-
20
-
-
84907212728
-
Germinal center B cell maintenance and differentiation are controlled by distinct NF-kB transcription factor subunits
-
Heise N, et al. (2014) Germinal center B cell maintenance and differentiation are controlled by distinct NF-kB transcription factor subunits. J Exp Med 211(10): 2103-2118.
-
(2014)
J Exp Med
, vol.211
, Issue.10
, pp. 2103-2118
-
-
Heise, N.1
-
21
-
-
0031964855
-
Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture
-
Franzoso G, et al. (1998) Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture. J Exp Med 187(2):147-159.
-
(1998)
J Exp Med
, vol.187
, Issue.2
, pp. 147-159
-
-
Franzoso, G.1
-
22
-
-
0031985287
-
Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses
-
Caamaño JH, et al. (1998) Nuclear factor (NF)-kappa B2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses. J Exp Med 187(2):185-196.
-
(1998)
J Exp Med
, vol.187
, Issue.2
, pp. 185-196
-
-
Caamaño, J.H.1
-
23
-
-
0035881959
-
Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines
-
Weih DS, Yilmaz ZB, Weih F (2001) Essential role of RelB in germinal center and marginal zone formation and proper expression of homing chemokines. J Immunol 167(4):1909-1919.
-
(2001)
J Immunol
, vol.167
, Issue.4
, pp. 1909-1919
-
-
Weih, D.S.1
Yilmaz, Z.B.2
Weih, F.3
-
24
-
-
0037107399
-
CD40 regulates the processing of NF-kappaB2 p100 to p52
-
Coope HJ, et al. (2002) CD40 regulates the processing of NF-kappaB2 p100 to p52. EMBO J 21(20):5375-5385.
-
(2002)
EMBO J
, vol.21
, Issue.20
, pp. 5375-5385
-
-
Coope, H.J.1
-
25
-
-
28844498364
-
Stabilization of basally translated NF-kappaB-inducing kinase (NIK) protein functions as a molecular switch of processing of NF-kappaB2 p100
-
Qing G, Qu Z, Xiao G (2005) Stabilization of basally translated NF-kappaB-inducing kinase (NIK) protein functions as a molecular switch of processing of NF-kappaB2 p100. J Biol Chem 280(49):40578-40582.
-
(2005)
J Biol Chem
, vol.280
, Issue.49
, pp. 40578-40582
-
-
Qing, G.1
Xiao, G.2
Qu, Z.3
-
26
-
-
14944362858
-
Regulation of plasma-cell development
-
Shapiro-Shelef M, Calame K (2005) Regulation of plasma-cell development. Nat Rev Immunol 5(3):230-242.
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.3
, pp. 230-242
-
-
Shapiro-Shelef, M.1
Calame, K.2
-
27
-
-
84923829724
-
The generation of antibodysecreting plasma cells
-
Nutt SL, Hodgkin PD, Tarlinton DM, Corcoran LM (2015) The generation of antibodysecreting plasma cells. Nat Rev Immunol 15(3):160-171.
-
(2015)
Nat Rev Immunol
, vol.15
, Issue.3
, pp. 160-171
-
-
Nutt, S.L.1
Hodgkin, P.D.2
Tarlinton, D.M.3
Corcoran, L.M.4
-
28
-
-
65649123826
-
IRF4: Immunity
-
Shaffer AL, Emre NC, Romesser PB, Staudt LM (2009) IRF4: Immunity. Malignancy! Therapy? Clin Cancer Res 15(9):2954-2961.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.9
, pp. 2954-2961
-
-
Shaffer, A.L.1
Emre, N.C.2
Romesser, P.B.3
Staudt, L.M.4
-
29
-
-
84962515123
-
Impairment of mature B Cell maintenance upon combined deletion of the alternative NF-kB transcription factors RELB and NF-?B2 in B cells
-
De Silva NS, Silva K, Anderson MM, Bhagat G, Klein U (2016) Impairment of mature B Cell maintenance upon combined deletion of the alternative NF-kB transcription factors RELB and NF-?B2 in B cells. J Immunol 196(6):2591-2601.
-
(2016)
J Immunol
, vol.196
, Issue.6
, pp. 2591-2601
-
-
De Silva, N.S.1
Silva, K.2
Anderson, M.M.3
Bhagat, G.4
Klein, U.5
-
30
-
-
33646555754
-
Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting
-
Casola S, et al. (2006) Tracking germinal center B cells expressing germ-line immunoglobulin gamma1 transcripts by conditional gene targeting. Proc Natl Acad Sci USA 103(19):7396-7401.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.19
, pp. 7396-7401
-
-
Casola, S.1
-
31
-
-
78149477766
-
Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
-
Victora GD, et al. (2010) Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell 143(4):592-605.
-
(2010)
Cell
, vol.143
, Issue.4
, pp. 592-605
-
-
Victora, G.D.1
-
32
-
-
67649216515
-
CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior
-
Silverstein RL, Febbraio M (2009) CD36, a scavenger receptor involved in immunity, metabolism, angiogenesis, and behavior. Sci Signal 2(72):re3.
-
(2009)
Sci Signal
, vol.2
, Issue.72
-
-
Silverstein, R.L.1
Febbraio, M.2
-
33
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
Subramanian A, et al. (2005) Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102(43):15545-15550.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
-
34
-
-
33645292598
-
A library of gene expression signatures to illuminate normal and pathological lymphoid biology
-
Shaffer AL, et al. (2006) A library of gene expression signatures to illuminate normal and pathological lymphoid biology. Immunol Rev 210:67-85.
-
(2006)
Immunol Rev
, vol.210
, pp. 67-85
-
-
Shaffer, A.L.1
-
35
-
-
84923778281
-
T-B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction
-
Liu D, et al. (2015) T-B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction. Nature 517(7533):214-218.
-
(2015)
Nature
, vol.517
, Issue.7533
, pp. 214-218
-
-
Liu, D.1
-
36
-
-
79961233459
-
Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development
-
Hu H, et al. (2011) Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development. Proc Natl Acad Sci USA 108(31):12827-12832.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.31
, pp. 12827-12832
-
-
Hu, H.1
-
37
-
-
78650907445
-
A single NF?B system for both canonical and non-canonical signaling
-
Shih VF, Tsui R, Caldwell A, Hoffmann A (2011) A single NF?B system for both canonical and non-canonical signaling. Cell Res 21(1):86-102.
-
(2011)
Cell Res
, vol.21
, Issue.1
, pp. 86-102
-
-
Shih, V.F.1
Tsui, R.2
Caldwell, A.3
Hoffmann, A.4
-
38
-
-
84880838774
-
B cell localization: Regulation by EBI2 and its oxysterol ligand
-
Gatto D, Brink R (2013) B cell localization: Regulation by EBI2 and its oxysterol ligand. Trends Immunol 34(7):336-341.
-
(2013)
Trends Immunol
, vol.34
, Issue.7
, pp. 336-341
-
-
Gatto, D.1
Brink, R.2
-
39
-
-
84892546134
-
Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation
-
Goenka R, et al. (2014) Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation. J Exp Med 211(1):45-56.
-
(2014)
J Exp Med
, vol.211
, Issue.1
, pp. 45-56
-
-
Goenka, R.1
-
40
-
-
12144286821
-
BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex
-
Hase H, et al. (2004) BAFF/BLyS can potentiate B-cell selection with the B-cell coreceptor complex. Blood 103(6):2257-2265.
-
(2004)
Blood
, vol.103
, Issue.6
, pp. 2257-2265
-
-
Hase, H.1
-
41
-
-
0029052398
-
Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers
-
Han S, et al. (1995) Cellular interaction in germinal centers. Roles of CD40 ligand and B7-2 in established germinal centers. J Immunol 155(2):556-567.
-
(1995)
J Immunol
, vol.155
, Issue.2
, pp. 556-567
-
-
Han, S.1
-
42
-
-
5644302162
-
Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase
-
Ramakrishnan P, Wang W, Wallach D (2004) Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity 21(4):477-489.
-
(2004)
Immunity
, vol.21
, Issue.4
, pp. 477-489
-
-
Ramakrishnan, P.1
Wang, W.2
Wallach, D.3
-
43
-
-
42149110830
-
Control of canonical NF-kappaB activation through the NIK-IKK complex pathway
-
Zarnegar B, Yamazaki S, He JQ, Cheng G (2008) Control of canonical NF-kappaB activation through the NIK-IKK complex pathway. Proc Natl Acad Sci USA 105(9): 3503-3508.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.9
, pp. 3503-3508
-
-
Zarnegar, B.1
Yamazaki, S.2
He, J.Q.3
Cheng, G.4
-
44
-
-
84867709361
-
The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry
-
Dominguez-Sola D, et al. (2012) The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry. Nat Immunol 13(11):1083-1091.
-
(2012)
Nat Immunol
, vol.13
, Issue.11
, pp. 1083-1091
-
-
Dominguez-Sola, D.1
-
45
-
-
84867730760
-
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers
-
Calado DP, et al. (2012) The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers. Nat Immunol 13(11):1092-1100.
-
(2012)
Nat Immunol
, vol.13
, Issue.11
, pp. 1092-1100
-
-
Calado, D.P.1
-
46
-
-
84959304876
-
NF-κB-inducing kinase is essential for B-cell maintenance in mice
-
Hahn M, Macht A, Waisman A, Hövelmeyer N (2016) NF-[ampi]]kappa;B-inducing kinase is essential for B-cell maintenance in mice. Eur J Immunol 46(3):732-741.
-
(2016)
Eur J Immunol
, vol.46
, Issue.3
, pp. 732-741
-
-
Hahn, M.1
Macht, A.2
Waisman, A.3
Hövelmeyer, N.4
-
47
-
-
84937688539
-
Conditional deletion of NF-kB-inducing kinase (NIK) in adult mice disrupts mature B cell survival and activation
-
Brightbill HD, et al. (2015) Conditional deletion of NF-kB-inducing kinase (NIK) in adult mice disrupts mature B cell survival and activation. J Immunol 195(3):953-964.
-
(2015)
J Immunol
, vol.195
, Issue.3
, pp. 953-964
-
-
Brightbill, H.D.1
-
48
-
-
0037818485
-
Gene expression profiling of plasma cells and plasmablasts: Toward a better understanding of the late stages of B-cell differentiation
-
Tarte K, Zhan F, De Vos J, Klein B, Shaughnessy J, Jr (2003) Gene expression profiling of plasma cells and plasmablasts: Toward a better understanding of the late stages of B-cell differentiation. Blood 102(2):592-600.
-
(2003)
Blood
, vol.102
, Issue.2
, pp. 592-600
-
-
Tarte, K.1
Zhan, F.2
De Vos, J.3
Klein, B.4
Shaughnessy, J.5
-
49
-
-
0028169302
-
Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation
-
Liou HC, Sha WC, Scott ML, Baltimore D (1994) Sequential induction of NF-kappa B/Rel family proteins during B-cell terminal differentiation. Mol Cell Biol 14(8):5349-5359.
-
(1994)
Mol Cell Biol
, vol.14
, Issue.8
, pp. 5349-5359
-
-
Liou, H.C.1
Sha, W.C.2
Scott, M.L.3
Baltimore, D.4
-
50
-
-
0030818183
-
B lymphocyte-specific, Cre-mediated mutagenesis in mice
-
Rickert RC, Roes J, Rajewsky K (1997) B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res 25(6):1317-1318.
-
(1997)
Nucleic Acids Res
, vol.25
, Issue.6
, pp. 1317-1318
-
-
Rickert, R.C.1
Roes, J.2
Rajewsky, K.3
-
51
-
-
34548237299
-
A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma
-
Saito M, et al. (2007) A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma. Cancer Cell 12(3):280-292.
-
(2007)
Cancer Cell
, vol.12
, Issue.3
, pp. 280-292
-
-
Saito, M.1
-
52
-
-
0024799016
-
Mechanism of antigen-driven selection in germinal centres
-
Liu YJ, et al. (1989) Mechanism of antigen-driven selection in germinal centres. Nature 342(6252):929-931.
-
(1989)
Nature
, vol.342
, Issue.6252
, pp. 929-931
-
-
Liu, Y.J.1
|